Thursday September 6, 2018 |
13:45 | Registration |
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14:30 | Welcome and opening |
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| Session Chair
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Prof. Tihomir TOMASIC (UNIVERSITY OF LJUBLJANA, Ljubljana, Slovenia) |
14:35 | KL01 - From Hits, to Leads to Chemical Probes: An Exciting Journey |
Prof. Cristina NEVADO (UNIVERSITY OF ZURICH, Zurich, Switzerland) |
| YMCS competition presentation session I |
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| Session Chair |
Dr Daniel MERK (ETH ZÜRICH, Zürich, Switzerland) |
15:05 | OC01 - Impact and Prediction of Binding Kinetics on in Vivo Drug Efficacy Winner of the young medicinal chemist meeting in France
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Dr Abdennour BRAKA (IRIM, Montpellier, France) |
15:25 | OC02 - Prospective Applications of Artificial Intelligence in de Novo Molecular Design for Drug Discovery |
Mr Lukas FRIEDRICH (ETH ZURICH, Zurich, Switzerland) |
15:45 | OC03 - Targeted Metabolomics Profiling as a Basis for Predictive Models in Multiple Sclerosis Research Winner of the young medicinal chemist meeting in Russia |
Mr Marat KASAKIN (INSTITUTE OF CHEMICAL BIOLOGY AND FUNDAMENTAL MEDICINE, Novosibirsk, Russia) |
16:05 | Flash poster presentations (0-10) |
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| FP01 - Targeting Basic Defect in Cystic Fibrosis: Discovery and Development of Novel Nanomolar F508-Del CFTR Correctors |
Dr Alejandra RODRIGUEZ-GIMENO (ISTITUTO ITALIANO DI TECNOLOGIA, Genova, Italy) |
| FP02 - Buruli Ulcer and The mTOR Pathway: Total Synthesis, Structure-Activity and Target Elucidation Studies of Mycolactones |
Prof. Matthias GEHRINGER (UNIVERSITY OF TUEBINGEN, Tuebingen, Germany) |
| FP03 - The Development of New Treatments for Multi-Drug Resistant Tuberculosis |
Ms Lisa BARBARO (MONASH UNIVERSITY, Reservoir, Australia) |
| FP04 - Synthesis and Characterisation of Psoralen Derivates as Inhibitors of The β5i Subunit of the Immunoproteasome |
Ms Eva Shannon SCHIFFRER (UNIVERSITY OF LJUBLJANA, FACULTY OF PHARMACY, Zirovnica, Slovenia) |
| FP05 - Fragment-Based Approach Applied to The Discovery of Protein-Protein Interaction Stabilisers |
Mr Dario VALENTI (TAROS CHEMICALS GMBH & CO. KG, Dortmund, Germany) |
| FP06 - The Use of Irreversible Ligands in the Quest to Obtain the First Ligand-Bound X-Ray Structures of The Adenosine A1 Receptor |
Dr Manuela JORG (MONASH UNIVERSITY, Parkville, Australia) |
| FP07 - Inhibitors of Human Sialyltransferases as Novel Anti-Metastatic Agents |
Mr Chris DOBIE (UNIVERSITY OF WOLLONGONG, Gwynneville, Australia) |
| FP08 - 3-Oxabicyclo[4.1.0]Heptane: A Bioisostere for Morpholine as a Kinase Hinge Binding Moiety |
Mr Declan SUMMERS (GLAXOSMITHKLINE, Stevenage, United Kingdom) |
| FP09 - Development of Small-Molecule Inhibitors of Adipose Triglyceride Lipase (ATGL) |
Ms Anna MIGGLAUTSCH (TU GRAZ, Graz, Austria) |
| FP10 - Covalent Fragment-Based Discovery of New Mura Inhibitors |
Dr Martina HRAST (FAKULTETA ZA FARMACIJO, Ljubljana, Slovenia) |
16:25 | Coffee Break |
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| YMCS competition presentation session II |
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| Session Chair |
Dr Kristina GONCHARENKO (SPIROCHEM AG, Basel, Switzerland) |
16:40 | OC04 - The Design and Synthesis of Bromodomain Photoaffinity Probes
Winner of the young medicinal chemist meeting in the United Kingdom |
Mr David FALLON (GLAXOSMITHKLINE, Stevenage, United Kingdom) |
17:00 | OC05 - Gemini-Type Protacs: a Small Molecule-Based Strategy for Self-directed Inactivation of Cereblon |
Dr Christian STEINEBACH (UNIVERSITY OF BONN, Bonn, Germany) |
17:20 | OC06 - Investigation of Direct Effect of Psychoactive Compounds on Invertebrate Neurons in Real Time Winner of the young medicinal chemist meeting in Hungary |
Dr Gabor MAASZ (HUNGARIAN ACADEMY OF SCIENCES, Budapest, Hungary) |
17:40 | OC07 - Hydrogen peroxide sensitive prodrugs of methotrexate and aminopterin for the treatment of rheumatoid arthritis Winner of the young medicinal chemist meeting in Denmark |
Dr Jorge PEIRO CADAHIA (NUEVOLUTION A/S, Copenhagen, Denmark) |
18:00 | Flash poster presentations (10-20) |
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| FP11 - Rational Design of Optimized Allosteric Effectors of Cathepsins K and S Based on Succinimide-Glycinate Scaffold |
Ms Tjasa GORICAN (UNIVERSITY OF LJUBLJANA, Ljubljana, Slovenia) |
| FP12 - Covalent Inhibition with Terminal Alkyne As ‘Inert’ Electrophile |
Mrs Elma MONS (LEIDEN UNIVERSITY MEDICAL CENTER, Leiden, The Netherlands) |
| FP13 - Exploration of Chemical Space of Two Classes of INHA Inhibitors |
Dr Izidor SOSIC (UNIVERSITY OF LJUBLJANA, Ljubljana, Slovenia) |
| FP14 - Late-Stage Functionalization of Peptides: Novel Site-Selective Modification & Bioconjugation |
Dr Anaïs NOISIER (ASTRAZENECA, Mölndal, Sweden) |
| FP15 - Identification of A GSK-3β/CK-1δ Inhibitor: Dual Target and Dual Mechanisms of Action as Possible Strategy for The Treatment of Parkinson’s Disease. |
Prof. Stephanie FEDERICO (UNIVERSITY OF TRIESTE, Trieste, Italy) |
| FP16 - Discovery of Benzothiazole-Based DNA Gyrase and Topoisomerase IV Inhibitors with Broad Spectrum Antibacterial Activity |
Ms Martina DURCIK (UNIVERSITY OF LJUBLJANA, Ljubljana, Slovenia) |
| FP17 - Development of Peptides as Therapeutics for Pharmacological Intervention in Vital Protein Cascades |
Dr Christina LAMERS (UNIVERSITY OF BASEL, Leipzig, Germany) |
| FP18 - Deep Learning Applications in The Design and Identification of Antibacterial Compounds |
Dr Marko JUKIC (FAKULTETA ZA FARMACIJO, UNIVERSITY OF LJUBLJANA, Ljubljana, Slovenia) |
| FP19 - The Design and Synthesis of Novel Inhibitors of the Notch Activation Complex Kinase for Notch Mediated Tumorigenesis |
Ms Tanya KELLEY (UNIVERSITY OF MIAMI, miami, United States) |
18:20 | Poster presentation session 1 (Odd numbers) & Networking drink |
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20:00 | End of the day |
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20:15 | Optional Networking Event (until 21:30) |
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Friday September 7, 2018 |
| YMCS competition presentation session III |
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| Session Chair |
Dr Ziga JAKOPIN (UNIVERSITY OF LJUBLJANA, Ljubljana, Slovenia) |
08:30 | OC08 - Fosmidomycin Analogs as Antimalarial and Antitubercular Agents - a Prodrug Approach Winner of the young medicinal chemist meeting in Belgium (KVCV) |
Ms Charlotte COURTENS (UGENT, Gent, Belgium) |
08:50 | OC09 - Metal-Chelating Acetohydroxamic Acids against Hepatitis C Virus and Flaviviruses
Winner of the young medicinal chemist meeting in Greece |
Ms Erofili GIANNAKOPOULOU (NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS, Athens, Greece) |
09:10 | OC10 - Elucidation of the Antifungal Mechanism of Action of Bis-Guanylhydrazones Winner of the young medicinal chemist meeting in Serbia |
Ms Jelena LAZIC (UNIVERSITY OF BELGRADE, FACULTY OF CHEMISTRY, Belgrade, Serbia) |
09:30 | OC11 - Discovery and Optimisation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors Winner of the young medicinal chemist meeting in Slovenia |
Dr Nace ZIDAR (UNIVERSITY OF LJUBLJANA, Ljubljana, Slovenia) |
09:50 | OC12 - The Effect of Singlet Oxygen Production and Lipophylicity of the Photosensitizer in Photodynamic Activity of N-Methylated and N-Oxsidised Pyridylporphyrins Winner of the young medicinal chemist meeting in Croatia |
Ms Martina MUSKOVIC (UNIVERSITY OF RIJEKA, Rijeka, Croatia) |
10:10 | Coffee Break |
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| YMCS competition presentation session IV |
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| Session Chair |
Mr Roman SINK (UNIVERSITY OF LJUBLJANA FACULTY OF PHARMACY, Ljubljana, Slovenia) |
10:30 | OC13 - Synthesis and Biological Evaluation of Bia 10-2474: an Irreversible and Aspecific Faah Inhibitor Winner of the young medicinal chemist meeting in The Netherlands |
Dr Anthe JANSSEN (LEIDEN UNIVERSITY, Leiden, The Netherlands) |
10:50 | OC14 - Methylene - Cycloalkylacetate (mca) as Novel Neurotropic Agents Winner of the young medicinal chemist meeting in Israel |
Mr David LANKRI (HEBREW UNIVERSITY, Jerusalem, Israel) |
11:10 | OC15 - Development of Release-and-Report Kinase Inhibitors as Molecular Tools for Investigating Neurodegenerative Disorders Winner of the young medicinal chemist meeting in Sweden |
Dr Cassandra LEE FLEMING (UNIVERSITY OF GOTHENBURG, Gothenburg, Sweden) |
11:30 | OC16 - Piperazine Derivatives as a Novel, Active Histamine h3 Receptor Ligands Winner of the young medicinal chemist meeting in Poland |
Dr Katarzyna SZCZEPANSKA (JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE, Krakow, Poland) |
11:50 | Lunch & Poster presentation session 2 (Even numbers) |
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| YMCS competition presentation session V |
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| Session Chair |
Prof. Emmanouil FOUSTERIS (UNIVERSITY OF PATRAS, Patras, Greece) |
13:15 | OC17 - Development of Aminoxyrone as the First-in-Class hsp90 C-Terminal Domain Dimerization Inhibitor
Winner of the young medicinal chemist meeting in Germany |
Prof. Finn HANSEN (UNIVERSITÄT LEIPZIG, Leipzig, Germany) |
13:35 | OC18 - How Can We Inhibit a Protein that is Intrinsically Disordered? Androgen Receptor – epi-001 a Case Study
Winner of the young medicinal chemist meeting in Spain |
Dr Marta FRIGOLE-VIVAS (INSTITUTE FOR RESEARCH IN BIOMEDICINE (IRB BARCELONA), Dresden, Germany) |
13:55 | OC19 - Kinase Templated Abiotic Reaction: from Promiscuity to Selectivity Winner of the young medicinal chemist meeting in Switzerland |
Mr Jacques SAARBACH (UNIVERSITÉ DE GENÈVE, Geneve 4, Switzerland) |
14:15 | OC20 - The Best of Three Worlds: Tackling Multidrug Resistance through Phytochemical, Biological and Computational Approaches
Winner of the young medicinal chemist meeting in Portugal |
Dr Ricardo FERREIRA (UPPSALA UNIVERSITY, Uppsala, Sweden) |
14:35 | OC21 - Targeting Zinc-Finger Proteins in Cancer and Viral Infections
Winner of the young medicinal chemist meeting in Italy |
Dr Mattia MORI (UNIVERSITY OF SIENA, Siena, Italy) |
14:55 | Voting break |
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15:10 | KL02 - My Lessons in Drug Discovery |
Dr Marton CSEKEI (SERVIER RESEARCH INSTITUTE OF MEDICINAL CHEMISTRY, Budapest, Hungary) |
15:40 | Closing and award ceremony |
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