| Confirmed Plenary Speakers (to Date) |
| Keynote Lecture |
|
| Thursday 08/09/2022 |
| 14:15 | Registration |
|
| 15:00 | Welcome and Opening |
Dr Maria DUCA (UNIVERSITY OF CÔTE D'AZUR, Nice, France)
Prof. Rui MOREIRA (UNIVERSITY OF LISBON, Lisbon, Portugal) |
| 15:15 | KL01 - "All Models are Wrong, Some are Useful". The Medicinal Chemist is Never Better Than the Biological Models Available to Assess Compound Properties |
Prof. Benoit DEPREZ
(INSTITUT PASTEUR DE LILLE, Lille, France) |
| 15:45 | EFMC-YMCS Competition Presentation Session I |
|
| Session Chair: |
Dr Maria DUCA
(UNIVERSITY OF CÔTE D'AZUR, Nice, France) |
| 15:45 | OC01 - Degrading Into Opportunities: Self-Immolation as Mechanism for Artificial Signal Transduction
Winner of the young medicinal chemist meeting in Denmark |
Dr Kaja BORUP LØVSCHALL
(TECHNICAL UNIVERSITY OF DENMARK, København Ø, Denmark) |
| 16:05 | OC02 - From a Helix to a Cycle: Peptide Macrocylization Strategies to Develop New Antimicrobial Agents
Winner of the young medicinal chemist meeting in Italy
|
Dr Francesco MERLINO
(UNIVERSITY OF NAPLES, FEDERICO II, Naples, Italy) |
| 16:25 | OC03 - Disruption of Mitochondrial Redox Homeostasis by Enzymatic Activation of a Trialkylphosphine Probe
Winner of the young medicinal chemist meeting in Switzerland
|
Ms Jade NGUYEN
(EPFL, Geneva, Switzerland) |
| 16:45 | Flash Poster Presentations (Part I) |
|
| FP01 – Triazine-Based Small Molecules as Novel PD-L1 Modulators |
Ms Giulia ASSONI
(UNIVERSITY OF TRENTO, Trento, Italy) |
| FP02 - Synthesis and Preclinical Validation of Limks Inhibitors: Promising Drugs for Osteosarcoma Treatment? |
Mr Rayan BERABEZ
(UNIVERSITÉ D'ORLÉANS, ORLEANS, France) |
| FP03 - Development of Encoded Combinatorial Chemistry for The Identification of Specific Ligands of G-Quadruplex DNA Structures |
Dr Gilles DEGOTTE
(I2BM/UNIVERSITY GRENOBLE ALPES, Grenoble, France) |
| FP04 - Synthesis and Biological Activity of Novel Azoniaspiro Type Quaternary Fluoroquinolones |
Dr Joanna FEDOROWICZ
(MEDICAL UNIVERSITY OF GDANSK, Gdansk, Poland) |
| FP05 - Development of Novel Necroptosis Inhibitors Targeting RIPK1 |
Ms Lara FIDALGO
(FF.ULISBOA, Lisboa, Portugal) |
| FP06 - Discovery of JNJ-1245, a Novel and Potent Fluoroallylamide MCL-1 Inhibitor for the Treatment of Hematologic Malignancies |
Dr Soufyan JERHAOUI
(JANSSEN PHARMACEUTICA NV, Beerse, Belgium) |
| FP07 - Target-Directed Dynamic Combinatorial Chemistry Towards the Discovery of Sars-Cov-2 Anti-Virals Targeting NSP10 |
Dr Gwenaelle JÉZÉQUEL
(HZI, Braunschweig, Germany) |
| FP08 - Panicein a Hydroquinone and Analogs Overcome Chemotherapy Resistance in Cancer Cell |
Mrs Sandra KOVACHKA
(UNIVERSITÉ COTE D'AZUR, Nice, France) |
| FP09 - Development of Bioorthogonal Palladium Catalysed Reactions for Specific Anticancer Drug Delivery |
Ms Marine LEFEVRE
(UCLOUVAIN, Louvain la Neuve, Belgium) |
| FP10 - Design, Synthesis & Evaluation of Novel Aminopeptidase Inhibitors as Potent Antimalarials |
Ms Mahta MANSOURI
(MONASH INSTITUTE OF PHARMACEUTICAL SCIENCES, Parkville, Australia) |
| FP15 - Synthesis and Biological Evaluation of Schistosoma Mansoni Sirtuin2 (SMSIRT2) Inhibitors |
Dr Beatrice NOCE
(SAPIENZA, UNIVERSITY OF ROME, Rome, Italy) |
| FP16 - Design, Synthesis and Biological Evaluation of New Rna Ligands Targeting miRNA-210: Modulation of the Circadian Clock for Cancer Therapy |
Mr Marc PANOSETTI
(INSTITUT DE CHIMIE DE NICE - UNIVERSITÉ COTE D'AZUR, Nice, France) |
| FP17 - A Small Fluorescent Ligand to Investigate Soluble Epoxide Hydrolase Engagement in Living Cells |
Ms Julia SCHOENFELD
(GOETHE-UNIVERSITY, Frankfurt am Main, Germany) |
| FP18 - Bactericidal Autophagy Inhibitors to Treat Recurrent Infections and Cancer |
Mrs Alessandra UGOLINI
(FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IIT), Genoa, Italy) |
| 17:15 | Coffee Break & Exhibition |
|
| EFMC-YMCS Competition Presentation Session II |
|
| Session Chair: |
Dr Michele MARI
(UNIVERSITY OF URBINO, Urbino, Italy) |
| 17:35 | OC04 - Epitope Identification, a Case Study: Nanobodies Binding to MGLU5 Receptor
Winner of the young medicinal chemist meeting in France |
Ms Floriane ESHAK
(UNIVERSITY PARIS CITÉ, Paris, France) |
| 17:55 | OC05 - Studies on the Synthesis and Anticancer Potential of Novel 2,4-Diaminopyrimidine Derivatives
Winner of the young medicinal chemist meeting in Turkey
|
Dr Deniz LENGERLI
(GAZI UNIVERSITY FACULTY OF PHARMACY, Ankara, Turkey) |
| 18:15 | OC06 - Unraveling the Potential of Multicomponent Reactions in Drug Discovery
Winner of the young medicinal chemist meeting in Spain |
Mr Pau Nadal RODRÍGUEZ
(UNIVERSITY OF BARCELONA, Barcelona, Spain) |
| 18:35 | EFMC-YMCS Poster Presentation Session 1 (Odd),
Networking & Exhibition |
|
| 20:30 | End of the Day |
|
| Friday 09/09/2022 |
| 08:40 | EFMC-YMCS Competition Presentation Session III |
|
| Session Chair: |
Dr Stéphane AZOULAY
(UNIVERSITY OF CÔTE D'AZUR, Nice, France) |
| 08:40 | OC07 - Hydrophilic and Lipophilic Derivatives of Protulactone A: Synthesis, Antiproliferative Activity and Sar Analysis
Winner of the young medicinal chemist meeting in Serbia |
Ms Sanja DJOKIC
(UNIVERSITY OF NOVI SAD, Novi Sad, Serbia) |
| 09:00 | OC08 - Advances in the Development of Novel Therapeutics Targeting Neurodegenerative Diseases
Winner of the young medicinal chemist meeting in Germany (DPhG) |
Dr Steffen POCKES
(UNIVERSITY OF REGENSBURG, Regensburg, Germany) |
| 09:20 | OC09 - Design, Synthesis and Biological Evaluation of Novel P53 Activators by Targeting P53 Protein-Protein Interactions
Winner of the young medicinal chemist meeting in Portugal |
Dr Margarida ESPADINHA
(UANTWERPEN, Antwerp, Belgium) |
| 09:40 | OC10 - Elevated Vacuolar Uptake of Fluorescently Labeled Antifungal Drug Caspofungin Predicts Echinocandin Resistance in Pathogenic Yeast
Winner of the young medicinal chemist meeting in Israël |
Mr Jaber QAIS
(TEL AVIV UNIVERSITY, taiybe, Israel) |
| 10:00 | Flash Poster Presentations (Part II) |
|
| FP11 - Antibody-Protac Conjugates: An Approach for Targeted Selective BRD4 Degradation in HER2+ Phenotypes |
Dr Maria MANEIRO
(UNIVERSIDADE DE SANTIAGO DE COMPOSTELA, Santiago de Compostela, Spain) |
| FP12 - Preclinical Evaluation of Antibody Recruiting Glycodendrimers (ARGs) for Cancer Therapy |
Dr Angela MARTIN SERRANO ORTIZ
(UNIVERSITÉ GRENOBLE-ALPES, Grenoble, France) |
| FP13 - Development of Orally Available Cyclic Peptide Therapeutics |
Mr Manuel MERZ
(SWISS FEDERAL INSTITUTE OF TECHNOLOGY LAUSANNE (EPFL), Lausanne, Switzerland) |
| FP14 - Sar of Triquinazine, a Class of Potent Janus Kinase Inhibitors |
Ms Kleni MULLIRI
(UNIVERSITY OF BERN, Bern, Switzerland) |
| FP19 - Potent and Specific Activators for The Mitochondrial Sirtuins SIRT3 And SIRT5 |
Dr Clemens ZWERGEL
(SAPIENZA UNIVERSITY OF ROME, Rome, Italy) |
| 10:10 | Coffee Break |
|
| 10:40 | EFMC-YMCS Competition Presentation Session IV |
|
| Session Chair: |
Dr Maja BEUS
(INSTITUTE FOR MEDICAL RESEARCH, Durham, United States) |
| 10:40 | OC11 - A Chemical Biological Approach to Study GPCRS: Labeling the Adenosine A1 Receptor Using an Electrophilic Covalent Probe
Winner of the young medicinal chemist meeting in The Netherlands |
Mr Bert BEERKENS
(LEIDEN UNIVERSITY, Leiden, The Netherlands) |
| 11:00 | OC12 - Indole and Pyrazole as Versatile Scaffolds for Biological Active Compounds: New Chimeric Kinase and Bromodomain Inhibitors
Winner of the young medicinal chemist meeting in Greece |
Mrs Amalia KALAMPALIKI
(NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS, Athens, Greece) |
| 11:20 | OC13 - The Complementarity Principle in Docking Procedures: Evaluation of the Correctness of Binding Poses
Winner of the young medicinal chemist meeting in Croatia
|
Dr Hrvoje RIMAC
(UNIVERSITY OF ZAGREB, Zagreb, Croatia) |
| 11:40 | OC14 - Development of Multifunctional Buche Inhibitors and 5-HT6R Antagonists with Beta-Amyloid Anti-Aggregation Properties as Potential Disease-Modifying Agents against Alzheimer’s Disease
Winner of the young medicinal chemist meeting in Poland |
Mr Tomasz WICHUR
(UNIWERSYTET JAGIELLONSKI COLLEGIUM MEDICUM , Krakow, Poland) |
| 12:00 | Lunch, Networking & Exhibition |
|
| 12:30 | EFMC-YMCS Poster Presentation Session 2 (Even) |
|
| 13:45 | EFMC-YMCS Competition Presentation Session V |
|
| Session Chair: |
Dr Kristina GONCHARENKO
(ZIFO RND SOLUTIONS, Basel, Switzerland) |
| 13:45 | OC15 - Breaking the Paradigm: Radiolabelled CCK2R Antagonists Are Superior to Radiolabelled Agonists in In Vivo Setting
Winner of the young medicinal chemist meeting in Slovenia |
Ms Doroteja NOVAK
(UNIVERSITY OF LJUBLJANA, Ljubljana, Slovenia) |
| 14:05 | OC16 - Discovery, Characterization and Engineering of Ligases for Amide Synthesis
Winner of the young medicinal chemist meeting in United Kingdom
|
Mr Michael ROWLINSON
(UNIVERSITY OF MANCHESTER, Manchester, United Kingdom) |
| 14:25 | OC17 - Design, Synthesis, and Preliminary Biological Evaluation of New Boronic Acids Derivatives
Winner of the young medicinal chemist meeting in Czech Republic
|
Mr Petr SLECHTA
(CHARLES UNIVERSITY, Hradec Králové, Czech Republic) |
| 14:45 | OC18 - Unravelling HIDO1 Conformational Dynamic to Guide the Discovery of New Inhibitors
Winner of the young medicinal chemist meeting in Belgium (SRC) |
Ms Manon MIRGAUX
(UNIVERSITÉ DE NAMUR, Namur, Belgium) |
| 15:05 | OC19 - Fighting Chemistry with Chemistry - New Antidotes against Nerve Agent Intoxication
Winner of the young medicinal chemist meeting in Sweden |
Mr Norman HOSTER
(UMEA UNIVERSITY, Umea, Sweden) |
| 15:25 | Voting Break |
|
| 15:40 | KL02 - Medicinal Chemistry Today: Be Prepared for the Unexpected! |
Dr Gerhard MUELLER
(ANAVO THERAPEUTICS, Basel, Germany) |
| 16:10 | Closing and Award Ceremony |
|
| 16:30 | End of the Symposium |
|
| 16:45 | Optional Programme |
|
| Session Chair: |
Dr Kristina GONCHARENKO
(ZIFO RND SOLUTIONS, Basel, Switzerland) |
| 16:45 | EFMC-YSN Soft Skills Training (1) - Reaxys Workshop: A Tandem Tour to Unveil the Profile of An Active Molecule |
Dr Giulia MONCELSI
(ELSEVIER LIFE SCIENCES, Amsterdam, The Netherlands) |
| 17:30 | EFMC-YSN Soft Skills Training (2) - Reaching Out: Effective Communication and Networking for Scientists |
Dr David PERALTA
(CHEMMEDCHEM/CHEMISTRY EUROPE, Weinheim, Germany) |
| 18:15 | End of the Optional Programme |
|
