SPICA 2014

15th International Symposium on Preparative and Industrial Chromatography and Allied Techniques

 Basel, Switzerland    October 5-8, 2014

Invited Speakers

Keynote Lecture
Industrial Preparative HPLC for Production of API Including Most Common Unit Operations; Membrane Operations, Evaporation, Crystallization

 Roman BURJA
Roman BURJA
LEK PHARMACEUTICALS D.D., Menges, Slovenia
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Keynote Lecture
Continuous Processing by CCC/CPC: Where to Plug and How to Play When Everything is Fluid

 Svetlana IGNATOVA
Svetlana IGNATOVA
BRUNEL UNIVERSITY, Uxbridge, United Kingdom
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Keynote Lecture
Multi-Column Chromatography: Challenges and Opportunities

 Yoshiaki KAWAJIRI
Yoshiaki KAWAJIRI
GEORGIA INSTITUTE OF TECHNOLOGY, Atlanta, United States
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Keynote Lecture
Peptide Purification: State-of-the-Art and Challenges

 Thomas MEIER
Thomas MEIER
BACHEM AG, Bubendorf, Switzerland
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Keynote Lecture
Pharmaceutical Small Molecule Purification: Where Are We and Where Do We Need to Be?

 Larry MILLER
Larry MILLER
AMGEN, Cambridge, United States
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Keynote Lecture
Chromatographer: What Could Modeling Do for You?

 Roger-Marc NICOUD
Roger-Marc NICOUD
FOUNDER AND FORMER CEO NOVASEP, CONSULTANT, Nancy, France
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Keynote Lecture
Chromatography and Crystallization: Good Partners in Separating Enantiomers

 Andreas SEIDEL-MORGENSTERN
Andreas SEIDEL-MORGENSTERN
MAX PLANCK INSTITUTE FOR DYNAMICS OF COMPLEX TECHNICAL SYSTEMS, Magdeburg, Germany
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Oral Communications

Highly Active Small Molecules and Peptides: Intrinsic Reduction of Risks by the Use of Preparative Chromatography and Flow Technologies

Ulf ALTENHOENER
LONZA AG, Aarau , Switzerland
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Modeling and Optimization of the Twin Column Capture SMB Process

Daniel BAUR
ETH ZÜRICH, Zurich, Switzerland
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Overcoming Challenges in the Industrial Production of OMEGA-3S

Jean BLEHAUT
NOVASEP GROUP, Pompey, France

Advances in Model-Based Inline Peak Deconvolution: Process-Data-Based Model Calibration and Real-Time Pooling Decisions

Nina BRESTRICH
KARLSRUHE INSTITUTE OF TECHNOLOGY, Karlsruhe, Germany
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Peptide Purification Via Ion-Exchange Doped Reversed Phase Chromatography: a Combined Experimental and Modeling Approach

Gianluca BUFFOLINO
ZEOCHEM AG, Uetikon am See, Switzerland
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Extraction-Injection: an Alternative Sample Introduction Method for SFC

Geoffroy COX
PIC SOLUTION, Media, United States
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Implementation of Continuous Chromatography Under cGMP for the Pharmaceutical Industry

Olivier DAPREMONT
AMPAC FINE CHEMICALS, Rancho Cordova, United States
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HTS Chromatographic Platforms: Small is Beautiful

David DELVAILLE
MERCKSERONO, Martillac, France
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Methodology for Scale-Up in Countercurrent Chromatography

Karine FAURE
INSTITUT DES SCIENCES ANALYTIQUES, Villeurbanne, France
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Modelling and Simulation of the Purification of Cell Culture-Derived Influenza Virus Via Continuous Size Exclusion Chromatoghraphy

Laura M. FISCHER
MAX PLANCK INSTITUTE FOR DYNAMICS OF COMPLEX TECHNICAL SYSTEMS, Magdeburg, Germany
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Reliable Scale-Up from Analytical to Large Scale Instrumentation in Chiral Supercritical Fluid Chromatography

 Torgny FORNSTEDT
Torgny FORNSTEDT
KARLSTAD UNIVERSITY, Karlstad, Sweden
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Preparative Chiral Chromatography. Summa Chiralogica

 Pilar FRANCO
Pilar FRANCO
CHIRAL TECHNOLOGIES EUROPE, Illkirch, France
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Continuous Manufacturing in Biopharmaceutical Industries

Holger FROEHLICH
CLAUSTHAL UNIVERSITY OF TECHNOLOGY, Clausthal-Zellerfeld, Germany

Implementation of Model-Based Approach for Chromatography Development

Bertrand GUELAT
NOVARTIS PHARMA AG, Basel, Switzerland
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pH Zone Refining in Centrifugal Partition Extraction. A Step Change in Productivity for Liquid-Liquid Chromatography Processes?

Paul HELLIER
INSTITUT DE RECHERCHE PIERRE FABRE, GAILLAC, France
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A New Dynamic Fractionation Method and Column Design for Size Separation of Bio-Polymer Particles

Peter HEWITSON
BRUNEL INSTITUTE FOR BIOENGINEERING, Uxbridge, United Kingdom
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Three Column Intermittent Simulated Moving BED (3C-ISMB) Cromatoghraphy: Cascade Operation for Center-Cut Separations

Simon JERMANN
ETH ZÜRICH, Zurich, Switzerland
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Design of an Agarose Based Platform for Large Scale Chromatography

Hans JOHANSSON
PUROLITE, Uppsala, Sweden
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Integration of Continuous Precipitation and Flow Through Chromatography with Monoliths for Purification of Recombinant Antibodies

 Alois JUNGBAUER
Alois JUNGBAUER
UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES, Vienna, Austria
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Optimizing the Separation of MAB Charge Variants Using Model-Based Approaches

Rushd KHALAF
ETH ZÜRICH, Zurich, Switzerland
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Purification of an Intermediately Eluting Component from a Complex Mixture

Kiara KOCHENDOERFER
BASF SE, Ludwigshafen, Germany
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Separation of Lignans by Supercritical Fluid Simulated Moving BED

Ming-Tsai LIANG
I-SHOU UNIVERSITY, Kaohsiung, Taiwan
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Implementing Integrated Continuous Downstream Processing

Kathleen MIHLBACHLER
LEWA GMBH, Leonberg, Germany
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From Molecule to Process: Model-Based Design of Continuous Centrifugal Partition Chromatography

 Mirjana MINCEVA
Mirjana MINCEVA
TECHNISCHE UNIVERSITÄT MÜNCHEN, Freising, Germany
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Purification of Antibody Conjugates by MCSGP Chromatography

Thomas MÜLLER-SPÄTH
CHROMACON AG, Zurich, Switzerland
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Modelling and Optimization of Preparative Chromatography Separation of Rare Earth Elements

 Bernt NILSSON
Bernt NILSSON
LUND UNIVERSITY, Lund, Sweden
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High Yeld Protein Refolding by Integrating Single-Column Chromatoghraphy and Membrane Filtration

Sebastian NIMMIG
FRIEDRICH-ALEXANDER-UNIVERSITY, Hanau, Germany
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Hardware Solutions Enabling Continuous Biomanufacturing

Roger NORDBERG
GE HEALTHCARE, Uppsala, Sweden
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Integrated Reaction/Separation Process for High-Yield Pegylation

David PFISTER
ETH ZÜRICH, Zürich, Switzerland
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Unified Design of Chromatographic Separation Processes

 Tuomo SAINIO
Tuomo SAINIO
LAPPEENRANTA UNIVERSITY OF TECHNOLOGY, Lappeenranta, Finland
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Implementation of a Negative Mode Platform for Virus Purification

 Ricardo SILVA
Ricardo SILVA
IBET - INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECHNOLOGICA, Oeiras, Portugal
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Saturation Capacity for Proteins in Ion Exchange Chromatoghraphy

 Fabian STEINEBACH
Fabian STEINEBACH
ETH ZÜRICH, Zurich, Switzerland
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Scale-Up in Supercritical Fluid Chromatography

Abhijit TARAFDER
WATERS CORPORATION, Boston, United States
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Continuous Processing of Self-Cleaving Fusion Proteins by Matrix-Assisted Refolding Separation Using SMB Size Exclusion Chromatography with Buffer Recycling

Martin WELLHÖFER
CELONIC AG, Basel, Switzerland
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Integrated Counetr Current Chromatography (ICCC) - From SMB to a Fully Integrated Process

 Steffen ZOBEL-ROOS
Steffen ZOBEL-ROOS
CLAUSTHAL UNIVERSITY OF TECHNOLOGY, Clausthal-Zellerfeld, Germany
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Workshops

From Development to Commercial Scale: Rules to Scale up, QbD, Regulatory, Process Validation

 Alessandro BUTTE
Alessandro BUTTE
ETH ZURICH, Zurich, Switzerland
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Process Design for Purification of Biomolecules

 Alois JUNGBAUER
Alois JUNGBAUER
UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES, Vienna, Austria
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Multicolumn Processes: From Historical SMB to the Latest Advances in the Purification of Biomolecules

 Arvind RAJENDRAN
Arvind RAJENDRAN
UNIVERSITY OF ALBERTA, Edmonton, AB, Canada

Preparative HPLC: Phase Screening, Method Optimisation, Process Development. Troubleshooting a Preparative Chromatographic Device

Michael SCHULTE
MERCK KGAA, Darmstadt, Germany

Process Design for Purification of Small Molecules and Peptides

Jochen STRUBE
CLAUSTHAL UNIVERSITY OF TECHNOLOGY, Clausthal-Zellerfeld, Germany

Solving a Purification Process: Choice of the Appropriate Process (Centrifugal Partition Chromatography vs Countercurrent Chromatography, Batch vs Continuous, Low Pressure vs High Pressure, Liquid vs SFC)

Eric VALERY
NOVASEP, Pompey, France