International Symposium on Microscale Separations and Bioanalysis
Liège, Belgium July 3-6, 2022
Programme
Sunday July 3, 2022
10:00
Registration (until 18:20)
10:30
Short Courses (subject to separate registration)
10:30
Start of parallel sessions
Short course 1
Short course 2
Short course 3
Short course 1
10:30
Micro-pillar Array Columns: Concept, Possibilities and Applications
Prof. Gert DESMET VRIJE UNIVERSITEIT BRUSSEL (VUB), Brussels, Belgium
Short course 2
10:30
An Introduction to Biosensors
Dr Tatevik CHALYAN VRIJE UNIVERSITEIT BRUSSEL, Brussels, Belgium Prof. Heidi OTTEVAERE VRIJE UNIVERSITEIT BRUSSEL (VUB), Brussels, Belgium
Short course 3
10:30
CE-MS for Metabolomics: Principles and Applications
Dr Rawi RAMAUTAR LEIDEN UNIVERSITY, Leiden, The Netherlands
12:30
Lunch Bags (to be booked during registration)
13:30
Start of parallel sessions
Short course 4
Short Course 5
Short course 6
Short course 4
13:30
Liquid-phase Microextraction
Prof. Stig PEDERSEN BJERGAARD UNIVERSITY OF OSLO, Oslo, Norway
Short Course 5
13:30
New Quantitation and Validation Trends in Separation MS-Based Bioanalysis
Dr Víctor GONZÁLEZ-RUIZ UNIVERSITY OF GENEVA (SWITZERLAND), Geneva, Switzerland
Dr Víctor GONZÁLEZ-RUIZ
Vı́ctor González-Ruiz is a pharmacist (2008) and holds a M.S. in Pharmaceutical R&D (2009). He got a Ph.D. in Analytical Chemistry (2014) from the Complutense University of Madrid, developing LC- and fluorescence-based analytical techniques to study antitumor drugs and their mechanisms of action. In 2015 he joined the Analytical Sciences lab at the School of Pharmaceutical Sciences, University of Geneva, where he currently works as a research associate. His main research interest is the development of toxicology-oriented analytical (mainly CE-MS and LC-MS) and data handling strategies for metabolomics, in collaboration with the Swiss Center for Applied Human Toxicology.
Prof. Serge RUDAZ UNIVERSITY OF GENEVA, Geneva, Switzerland
Short course 6
13:30
Introducing Vortices in Microfluidic Devices for Analytical and Preparative Separations
Prof. Wim DE MALSCHE VRIJE UNIVERSITEIT BRUSSEL (VUB), Brussels, Belgium
Prof. Wim DE MALSCHE
Prof. Wim De Malsche obtained a degree in Bioengineering in 2004 at the Vrije Universiteit Brussel and a doctoral degree in 2008 in Applied Physics at the Mesa+ Institute for Nanotechnology (UTwente, NL) and in Engineering at the Vrije Universiteit Brussel on the topic of miniaturized analytical separation systems. He (co)founded the spin-off company PharmaFluidics based on his PhD research in 2010 and held (part-time) positions as CEO (2010-2014), CTO (2015-2017) and as director (2014-2018). Since 2015 he is full-time faculty member (currently Professor) at both the Department of Chemical Engineering and the Bioengineering Sciences Department at the VUB, leading the µFlow group (around 15 researchers). His research is centered around microfluidics and microreactors with a focus on enhancing mass transport and novel separation principles.
Dr Pierre GELIN VUB, Brussels, Belgium
16:15
Symposium Opening Ceremony
Prof. Marianne FILLET UNIVERSITY OF LIÈGE, Liege, Belgium Prof. Heidi OTTEVAERE VRIJE UNIVERSITEIT BRUSSEL (VUB), Brussels, Belgium
Session Chairs
Prof. Gert DESMET VRIJE UNIVERSITEIT BRUSSEL (VUB), Brussels, Belgium Prof. Jörg P. KUTTER UNIVERSITY OF COPENHAGEN, Copenhagen, Denmark
After a degree in Chemistry at the University of Oxford, Justin obtained his PhD from the University of Cambridge for the development and application of novel mass spectrometry approaches working with Professor Dame Carol Robinson. He was awarded fellowships from the Medical Research Council and Royal Society and appointed to faculty at the University of Oxford in 2012, where he is now Professor in Biophysical Chemistry. He is also Tutorial Fellow in Physical Chemistry at University College Oxford. Justin’s research has garnered an international reputation for innovative biophysical chemistry approaches, based on combing mass measurement with other experimental methods., simulations, and quantitative thermodynamic and kinetic analysis. This allows him and his group to change our thinking as to how proteins assemble, interact, and even evolve. This effort has been recognised by the Cell Stress Society international Alfred Tiessieres Award, the Howard Prize Lecture from the biophysical Science Institute at Durham and the Norman Heatley Award from the Royal Society of Chemistry in 2019. Justin is a founder of Refeyn Ltd, which provides mass photometry solutions to the life sciences community.
17:20
PL02 - Drops and MS: Separation and Analysis of Compounds and Cells in Nanoliter Volumes
Prof. Petra S. DITTRICH ETH ZURICH, Basel, Switzerland
Prof. Petra S. Dittrich is Associate Professor for Bioanalytics at the Department of Biosystems Science and Engineering, ETH Zürich. She develops microfluidic devices for the life sciences, particular for bioanalytical and diagnostic applications.
She studied chemistry at Bielefeld University (Germany) and Universidad de Salamanca (Spain) from 1993 to 1999. She earned her PhD degree at the Max Planck-Institute for Biophysical Chemistry (MPI Göttingen, Germany) in 2003. After another year as postdoctoral fellow at the MPI Göttingen, she had a postdoctoral appointment at the Institute for Analytical Sciences (ISAS Dortmund, Germany) (2004-2008). From 2008-2014, she was Assistant Professor at the Organic Chemistry Laboratories of the Department of Chemistry and Applied Biosciences (ETH Zurich). For research stays, she visited the Cornell University (Ithaca, USA, in 2002) and the University of Tokyo (Japan, in 2005).
18:10
Welcome Reception
Monday July 4, 2022
08:00
Registration
Session Chair
Prof. Jan VANFLETEREN IMEC & GHENT UNIVERSITY, Gent-Zwijnaarde, Belgium
Prof. Jan VANFLETEREN
Prof. Dr ir. Jan Vanfleteren received the Ph.D. degree in electronic engineering from Ghent University, Ghent, Belgium, in 1987. He is currently a principal member of technical staff with the Center for Microsystems Technology (CMST) of imec, the lnteruniversity Microelectronics Centre, based in Leuven, Belgium. Jan Vanfleteren is involved in the development of novel interconnection, assembly, and polymer microsystem technologies, especially for wearable and implantable electronics, biomedical, microfluidics, cell culturing, and tissue engineering applications. ln 2004, he became a part-time Professor with Ghent University. He is the co-author of over 200 papers in international journals and conferences. He holds more than 20 patents and patent applications. He is a member of IEEE, IMAPS and MRS.
08:30
PL03 - Emulating Organ-Organ Interaction Using Scalable Microfluidics and Multi-Cellular Spheroids
Dr Olivier FREY INSPHERO AG, Schlieren, Switzerland
Olivier Frey is Vice President and Head of Technology & Platforms at InSphero and leads the Microphysiological Systems and Organ-on-Chip programs. Before joining InSphero, he was group leader and SNF Ambizione fellow at the Department of Biosystems Science and Engineering of ETH Zurich, Switzerland. In the Bio Engineering Laboratory of Prof. Andreas Hierlemann he was responsible for the development of integrated microfluidic systems for single cell handling and 3D tissue cultures. Included are in particular multi-tissue systems, or so-called "Body-on-a-Chip" configurations based on 3D microtissue spheroids for perfusion culturing, on-chip and off-chip analysis and interaction. Olivier Frey received his Doctoral degree in Micro Engineering from EPF Lausanne, Switzerland, at Laboratory of Prof. Nico de Rooij, and a Diploma in Microtechnology, Mechanics and Economics from ETH Zürich.
Session 1 - Joint Session: Microfluidic Platforms for Integrated Separation and Detection & Microscale Sample Preparation for Bioanalysis
Session Chairs
Prof. Stig PEDERSEN BJERGAARD UNIVERSITY OF OSLO, Oslo, Norway Dr Barbara STADLOBER JOANNEUM RESEARCH, Weiz, Austria
Dr Barbara Stadlober is Principal Investigator at MATERIALS - the Institute for Surface Technologies and Photonics - of the JOANNEUM RESEARCH Forschungsgesellschaft mbH (JR) located in Austria. She studied Physics at the Karl-Franzens University in Graz and received a PhD from the Technical University in Munich-Garching. In 1996 she started her career as part of the technology development team of Siemens Halbleiter AG (later Infineon Technologies Austria) in Villach. She joined JR in 2002, where she started a research group dedicated to organic and printed electronics as well as large area micro/nanopatterning. Currently, Dr. Stadlober is head of the research group "Hybrid Electronics and Patterning". Her areas of interest range from organic thin-film transistors over printed piezoelectric sensors and nanogenerators to R2R UV-nanoimprinting for bionic, microoptical and microfluidic functional films. She authored more than 100 peer-reviewed publications and appears as inventor of more than 70 patents.
09:20
KL01 - Open Microfluidic Point-of-care Diagnostic Platform with Freely Configurable Detection Unit
Dr Claudia GAERTNER MICROFLUIDIC-CHIPSHOP, Jena, Germany
Dr Claudia Gärtner studied chemistry and biology and has earned her diploma and PhD in chemistry at the University of Düsseldorf in 1996. Between 1996 and 1999, she worked as an assistant to the Director at the Institute for Microtechnology in Mainz (IMM), where she coordinated large scale international projects (e.g. TMR-project MICROSYNC, LSF-project). In 1999 she was appointed Director of the Application Centre for Microtechnology in Jena, a daughter institution of the Fraunhofer Institute for Applied Optics and Precision Engineering. In 2002 she founded MFCS together with Dr. Holger Becker. Since April 2006 she is CEO of microfluidic ChipShop. She has been coordinator of numerous R&D projects on national and international level, including the FP 7 IP Multisense Chip. In 2017 she was decorated with the 3rd prize as Women Innovator competition by the European Commission. She is in the board of trustees of the German Museum in Munich and the advisory board of the Trade Fair in Erfurt, Thuringia, Germany. Lab-on-a-Chip system as bleed-to-read-systems including their manufacturing and commercialization are in her focus.
09:50
KL02 - New Trends Using Microchip Devices for Sample Treatment. A New Approached to Green Analytical Methods
Prof. Maria Dolores RAMOS PAYAN UNIVERSITY OF SEVILLE, Seville, Spain
Prof. Maria Dolores RAMOS PAYAN
Maria Ramos Payán is Doctor in Chemistry (Ph.D) and she is Associate Professor at University of Seville (Spain) at the Department of Analytical Chemistry. She has also developed her research at the University of Lund (Sweden), University of Copenhagen (Denmark), University of Chapel Hill (North Carolina, USA) and National Microelectronics Center (Barcelona). Her research interests focus on the development of new microextraction procedures and microfluidic chip devices for applications in biological and environmental samples.
10:20
Coffee break & Exhibition
Session Chairs
Prof. Stig PEDERSEN BJERGAARD UNIVERSITY OF OSLO, Oslo, Norway Dr Barbara STADLOBER JOANNEUM RESEARCH, Weiz, Austria
Dr Barbara Stadlober is Principal Investigator at MATERIALS - the Institute for Surface Technologies and Photonics - of the JOANNEUM RESEARCH Forschungsgesellschaft mbH (JR) located in Austria. She studied Physics at the Karl-Franzens University in Graz and received a PhD from the Technical University in Munich-Garching. In 1996 she started her career as part of the technology development team of Siemens Halbleiter AG (later Infineon Technologies Austria) in Villach. She joined JR in 2002, where she started a research group dedicated to organic and printed electronics as well as large area micro/nanopatterning. Currently, Dr. Stadlober is head of the research group "Hybrid Electronics and Patterning". Her areas of interest range from organic thin-film transistors over printed piezoelectric sensors and nanogenerators to R2R UV-nanoimprinting for bionic, microoptical and microfluidic functional films. She authored more than 100 peer-reviewed publications and appears as inventor of more than 70 patents.
10:50
OC01 - Novel Miniaturized and Microfluidic-Based Analytical Approaches for Isolation and Characterization of Extracellular Vesicles (EVs)
Prof. Myriam TAVERNA UNIVERSITY PARIS SACLAY, CHATENAY MALABRY, France
11:10
OC02 - Polymer Inclusion Membrane (PIM) Sampling Probe for Electric Field Driven Extraction of Drug Analytes from Biological Fluids
(YS)
Dr Hui Yin TEY UNIVERSITY OF TECHNOLOGY MALAYSIA, Skudai, Malaysia
Dr Hui Yin TEY
HuiYin is a final year Ph.D. student at the University of Technology Malaysia under the supervision of Assoc. Prof. Dr Hong Heng See. Her Ph.D. project focuses on the development of a electrophoretic sampling platform that is fabricated by a polymer inclusion membrane (PIM) for the extraction and preconcentration of the target pharmaceuticals from biological samples. Her research interests are in pharmaceutical analysis, miniaturized analytical techniques, separation science, microfluidics device, drug delivery system, pharmaceutical formulations and drug discovery. She joined Prof. Fabio Cicoira’s group in Polytechnique Montreal, Canada for a 7-month virtual research internship in 2020. Upon completing her Ph.D studies, HuiYin is open for collaborations and postdoctorate opportunities.
11:30
OC03 - Purification and Size-Fractionation of Milli-Liter DNA Samples in Minutes Using Electrohydrodynamic Migration
(YS)
Mr Paul BRUAND LAAS-CNRS, Toulouse, France
Mr Paul BRUAND
Paul Bruand is 3rd year PhD student at LAAS-CNRS, Toulouse, France. His thesis, in collaboration with Adélis company, aims to develop a technology for sample preparation of DNA, particularly in the field of circulating cell-free DNA.
11:50
OC04 - Controlling the Motion of Particles in Inertial Microfluidic Devices
Prof. Wim DE MALSCHE VRIJE UNIVERSITEIT BRUSSEL (VUB), Brussels, Belgium
Prof. Wim DE MALSCHE
Prof. Wim De Malsche obtained a degree in Bioengineering in 2004 at the Vrije Universiteit Brussel and a doctoral degree in 2008 in Applied Physics at the Mesa+ Institute for Nanotechnology (UTwente, NL) and in Engineering at the Vrije Universiteit Brussel on the topic of miniaturized analytical separation systems. He (co)founded the spin-off company PharmaFluidics based on his PhD research in 2010 and held (part-time) positions as CEO (2010-2014), CTO (2015-2017) and as director (2014-2018). Since 2015 he is full-time faculty member (currently Professor) at both the Department of Chemical Engineering and the Bioengineering Sciences Department at the VUB, leading the µFlow group (around 15 researchers). His research is centered around microfluidics and microreactors with a focus on enhancing mass transport and novel separation principles.
Session Chair
Prof. Anne VARENNE CHIMIE PARISTECH - PSL, Paris, France
Prof. Anne VARENNE
Anne Varenne is a full professor at Chimie ParisTech (University Paris Sciences and Letters, PSL). Doctor and engineer from Chimie ParisTech, she carries out her research in analytical sciences and microfluidic diagnostics dedicated to health and environment, through the understanding and characterization of interactions in solution or at interfaces, the design and characterization of nano-structures and the design of integrated miniaturized total analysis. She holds or has held various positions at the local, national and international levels. She is the head of the SEISAD research team at Institut of Chemistry for Life and Health Sciences of Chimie ParisTech- PSL. She is the director of the Graduate Program in Chemistry of University PSL (15 laboratories, 200 investigators, 200 PhD students,).
12:10
10 Poster Pitches
12:40
Lunch & Exhibition
13:10
Lunch Seminar - Refeyn
13:30
Poster Session
14:30
Start of parallel sessions
Session 2 - New Trends in MS and IMS for Bioanalysis
Session 3 - Microfluidic Platforms
Session 2 - New Trends in MS and IMS for Bioanalysis
Session Chair
Dr Tim CAUSON UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES VIENNA, Vienna, Austria
Dr Tim CAUSON
Tim Causon is Ass.Prof. and deputy head of the Institute of Analytical Chemistry at the University of Natural Resources and Life Sciences (BOKU), Vienna. His main areas of research are separation science, ion mobility-mass spectrometry, quantitative metabolomics, and analytical method development for diverse small molecule applications including metabolomics supporting microbial cell engineering. He is currently mentor of research project in the FWF Lise Meitner Program and is a faculty member of the Doctoral School Bioprocess Engineering. He is also a member of the Editorial Advisory Board of the international journal Analytica Chimica Acta and of the Training Committee of the Metabolomics Society. He has published more than 50 peer-reviewed publications including 3 book chapters.
14:30
KL03 - Clinical Proteomics with Trapped Ion Mobility Spectrometry and PASEF
Dr Florian MEIER FRIEDRICH-SCHILLER-UNIVERSITY JENA, Jena, Germany
Dr Florian MEIER
Prof. Dr Florian Meier-Rosar is an independent research group leader and Juniorprofessor at the Jena University Hospital (Germany), where he focuses on the development of mass spectrometry-based omics technologies and their application for the functional analysis of clinical specimens. A main focus is the integration of ion mobility spectrometry to increase throughput, sensitivity and coverage in proteomics. He accepted his current position after a short post-doctoral phase at the Max Planck Institute of Biochemistry. He received his PhD in Biochemistry from the Ludwig-Maximilian University Munich in 2018 for his research on novel data acquisition methods under the supervision of Prof. Matthias Mann. His research was awarded with the MPIB Junior Scientist’s Award in 2018 and the 2019 Wolfgang Paul Study Award of the German Mass Spectrometry Society.
15:00
OC05 - Improving the Resolving Power of a Compact High-Resolution Electrospray Ionization Ion Mobility Spectrometer
(YS)
Mr Christian THOBEN LEIBNIZ UNIVERSITY HANNOVER, Hannover, Germany
Mr Christian THOBEN
Mr. Christian Thoben studied electrical engineering and information technology at Leibniz University Hannover and has been a research assistant and PhD student at the Institute of Electrical Engineering and Measurement Technology in the Department of Sensors and Measurement Technology at Leibniz University Hannover since 2016. His research focuses on the optimization of compact high-resolution ion mobility spectrometers and their application in medical and environmental issues. For example, examining medical equipment and room air for traces of volatile anesthetics using GC-IMS. As well as the development of portable instruments for rapid on-site monitoring of pollutants or analytes, such as pesticides or pharmaceuticals, in liquids. In particular, using nano-HPLC as a pre-separation technique.
15:20
OC06 - Trapped Ion Mobility Mass Spectrometry of New Psychoactive Drugs: Fast Distinction and Assignment of Positional Isomers in Designer-Drug Mixtures
(YS)
Mr Hany MAJEED VU AMSTERDAM, AMSTERDAM, The Netherlands
Mr Hany MAJEED
I am a second year Ph.D. student at the group of Govert Somsen where I focus on developing novel identification techniques for new psychoactive substances (NPS). These NPS are close derivatives of conventional illicit drugs, such as MDMA and Mephedrone, used to circumvent the law. They often only differ by a functional group relocation or substitution. Although these changes seem small, they will lead to drugs of different legal status with little known on their potential health risks. These close isomers create a significant analytical challenge for forensic laboratories when traditional methods methods are used, such as LC-MS and GC-MS. Within our group we are therefore interested in more novel methods for the discrimination of isomeric drugs. We are currently heavily focused on ion mobility approaches.
15:40
OC07 - High Resolution Conformer Distribution Fingerprinting with IMS-MS for Exact N-Glycan Structure Determination
Dr Javier SASTRE TORANO UTRECHT UNIVERSITY, Utrecht, The Netherlands
Dr Javier SASTRE TORANO
Javier Sastre Toraño obtained a Ph.D. from Utrecht University (the Netherlands) on the development of capillary electrophoresis and ion mobility-mass spectrometry methods for glycan analysis. Currently, he is a research scientist at the Chemical Biology and Drug Discovery department at Utrecht University employing chemoenzymatically synthesized glycan standards for analytical method development to harness the biomedical potential of glycoscience. His main interest is in separation science, ion mobility spectrometry and mass spectrometry for glycan and glycoconjugate analysis.
Session 3 - Microfluidic Platforms
Session Chair
Prof. Wim DE MALSCHE VRIJE UNIVERSITEIT BRUSSEL (VUB), Brussels, Belgium
Prof. Wim DE MALSCHE
Prof. Wim De Malsche obtained a degree in Bioengineering in 2004 at the Vrije Universiteit Brussel and a doctoral degree in 2008 in Applied Physics at the Mesa+ Institute for Nanotechnology (UTwente, NL) and in Engineering at the Vrije Universiteit Brussel on the topic of miniaturized analytical separation systems. He (co)founded the spin-off company PharmaFluidics based on his PhD research in 2010 and held (part-time) positions as CEO (2010-2014), CTO (2015-2017) and as director (2014-2018). Since 2015 he is full-time faculty member (currently Professor) at both the Department of Chemical Engineering and the Bioengineering Sciences Department at the VUB, leading the µFlow group (around 15 researchers). His research is centered around microfluidics and microreactors with a focus on enhancing mass transport and novel separation principles.
14:30
KL04 - Microchips Design for Health and Environment
Prof. Anne VARENNE CHIMIE PARISTECH - PSL, Paris, France
Prof. Anne VARENNE
Anne Varenne is a full professor at Chimie ParisTech (University Paris Sciences and Letters, PSL). Doctor and engineer from Chimie ParisTech, she carries out her research in analytical sciences and microfluidic diagnostics dedicated to health and environment, through the understanding and characterization of interactions in solution or at interfaces, the design and characterization of nano-structures and the design of integrated miniaturized total analysis. She holds or has held various positions at the local, national and international levels. She is the head of the SEISAD research team at Institut of Chemistry for Life and Health Sciences of Chimie ParisTech- PSL. She is the director of the Graduate Program in Chemistry of University PSL (15 laboratories, 200 investigators, 200 PhD students,).
15:00
OC08 - Freeform-Based Microfluidic Devices for Conventional and Surface-Enhanced Raman Spectroscopy
Dr Qing LIU VRIJE UNIVERSITEIT BRUSSEL, Brussels, Belgium
Dr Qing LIU
Dr Ir. Qing Liu is a post-doc researcher at the Faculty of Engineering of the Vrije Universiteit Brussel (VUB). His research focuses on optofluidic lab-on-chip devices for molecular vibrational spectroscopy, Surface-Enhanced Raman Spectroscopy (SERS) and freeform optics. Qing received his B.S. degree in Remote Sensing Science and Technology in 2012 at the Beihang University in China and obtained his master’s degree in Optical Engineering at the University of Chinese Academy of Sciences. In 2018, Qing obtained his master’s degree in Management at the Solvay Business School of VUB.
15:20
OC09 - Microfluidic Capillary Electrophoresis Coupled to Surface-Enhanced Raman Spectrometry and the Synthesis of Nanoparticles for Selective Detection
Dr Anna TYCOVA INSTITUTE OF ANALYTICAL CHEMISTRY OF THE CAS, V.V.I., Brno, Czech Republic
Dr Anna TYCOVA
Anna Tycova is a postdoctoral research fellow at Institute of Analytical Chemistry of CAS in Brno, Czech Republic. She focuses on analytical tools for a definite identification of molecules via their structural characterization (mass spectrometry and surface-enhanced Raman spectrometry) and their coupling to capillary electrophoresis.
Anna studied chemistry at Palacky and Masaryk University, while her research was conducted at the Institute of Analytical Chemistry of CAS and University of Leipzig (Germany).
15:40
OC10 - Real-Time Particle Position Detection for Dynamic Optical Tweezers
(YS)
Mr Julian Alexander HANSS RWTH AACHEN UNIVERSITY, Aachen, Germany
Mr Julian Alexander HANSS
Julian Alexander Hanss was born on July 30th, 1991, in Flensburg, Germany. He visited school in Halle/ Saale for
12 years. In June 2010 he reached the higher education entrance qualification at Elisabeth‐Gymnasium Halle.
His advanced courses had been Mathematics & Physics.
Afterwards Julian Hanss worked as a volunteer at the teaching hospital Kröllwitz, Department for diagnostic
radiology from 09‐01‐2010 until 02‐28‐2011. Then he moved to Aachen starting his study career at RWTH
Aachen University in April 2011. Three years later in April 2014 Julian Hanss reached the Bachelor of Science,
course of study Physics. He wrote his Bachelor thesis at the organic surfaces group of Prof. Dr. Matthias Wuttig.
After half a year work and travel in the United States of America, mainly in Chicago, he continued studying in
the master course program with focus on condensed matter physics, which he completed successfully in
October 2016. The title of his Master thesis was “Systematic Size Variation of Locally Switched Phase Change
Materials for Surface Phonon Polariton Resonator Tuning”. His scientific supervisor had been Prof. Dr. Thomas
Taubner.
The most mentionable scientific publication during this time has been ‘Reversible optical switching of highly
confined phonon–polaritons with an ultrathin phasechange material’, Peining Li, Xiaosheng Yang, Tobias W.W.
Maß, Julian Hanss, Martin Lewin, Ann‐Katrin U. Michel, Matthias Wuttig & Thomas Taubner, Nature Mater. 15,
870‐875 (2016), doi: 10.1038/nmat4649.
Since February 2017 Julian Alexander Hanss works as a research assistant at the Chair for Laser Technology LLT
at the RWTH Aachen. His topic of research are dynamic optical tweezers for microparticles and cells, mentored
by Prof. Dr. Reinhart Poprawe and recently Prof. Dr. Constantin Häfner. The field of work spans from teaching
in the field of Laser technology for students of physics and engineering courses to projects in cooperation with
the Fraunhofer Institute for Laser Technology ILT.
16:00
Coffee break & Exhibition
16:30
Start of parallel sessions
Session 4 - Nanoscale Separation Systems for Interaction Studies
Session 5 - Sensor Fabrication Technologies
Session 4 - Nanoscale Separation Systems for Interaction Studies
Session Chair
Prof. Hervé COTTET UNIVERSITY OF MONTPELLIER, Montpellier, France
Prof. Hervé COTTET
Hervé Cottet (48) is full professor at the Max Mousseron Biomolecules Institute (IBMM) in Montpellier (France). Since 2012, he is the head of a Research Department (~15 permanent researchers) at the IBMM. His research work concentrates at the interface between separation sciences, pharmaceutical sciences, physical chemistry and polymers. He is developing CE methodologies and Taylor Dispersion Analysis (TDA) for the characterization of biopharmaceuticals (including vaccines), (bio)polymers, polyelectrolytes, drug delivery systems, dendrimers, nanoparticles, colloids and bacteria. He is both interested in fundamentals (mobility modeling, electrophoretic behavior) and practical (or industrial) applications of CE and TDA. Graduated from the Ecole Supérieure de Physique et Chimie Industrielles de Paris (ESPCI), he completed his PhD in analytical chemistry in 1999 at the Ecole Nationale Supérieure de Chimie de Paris (ENSCP- PSL, France) on Capillary Electrophoresis (CE). After a post-doc at the Technical University of Eindhoven (the Netherlands), he joined the University of Montpellier in 2000. He has co-authored more than 130 scientific articles dealing with CE and/or TDA.
16:30
KL05 - Size-Based Characterization of Multiple Bound Species Using Flow Induced Dispersion Analysis
Dr Henrik JENSEN FIDABIO, Copenhagen, Denmark
Dr Henrik JENSEN
Henrik Jensen (HJ) defended his phd at the university of Aarhus in 1999 in organic electrochemistry and subsequently complete a 4 year post doc at the Swiss Federal Institute of Technology at Lausanne (EPFL) focusing on developing and characterizing bioanalytical techniques. From 2003 to 2019, HJ held independent positions as assistant and associate professor at Copenhagen University focusing on research programs in physical and analytical chemistry. Part of this research lead to the formation of Fida Biosystems Aps in 2013. Since 2019 HJ has been the full time CSO of Fida Biosystems Aps. Researcher ID: B-4665-2011.
17:00
OC11 - Affinity Capillary Electrophoresis in Fragment-Based Drug Discovery Projects, a Tool for Hit Discovery and Binding Site Characterization
(YS)
Ms Clara DAVOINE UNIVERSITÉ DE NAMUR & UNIVERSITY OF LIÈGE, Namur, Belgium
Ms Clara DAVOINE
Clara Davoine is finishing her cotutelle Ph.D. at the Universities of Namur and Liege (Belgium) under the supervision of Dr. Lionel Pochet and Prof. Marianne Fillet. Her dissertation, “Development of new compounds targeting coagulation factor XIIa using innovative microfluidic assays in the context of fragment-based drug discovery,” aims to set affinity capillary electrophoresis assays that address the analytical challenges encountered in fragment-based drug discovery and to design potent factor XIIa inhibitors. On a broader scope, she is interested in biomolecular interaction studies, enzymology, and medicinal chemistry. Her research is supported by the Fonds National de la Recherche Scientifique – FNRS (Belgium), from which she is a Research Fellow.
17:20
OC12 - Development of Miniturized Affinity Columns for Specific Capture, Release and ToF-MS Detection of High Affinity Gag Ligands
Dr Frédéric JEANROY INSTITUT DES SCIENCES ANALYTIQUES, Villeurbanne, France
Session 5 - Sensor Fabrication Technologies
Session Chair
Dr Tatevik CHALYAN VRIJE UNIVERSITEIT BRUSSEL, Brussels, Belgium
16:30
KL06 - Novel Origami Foil Based Microfluidic Chip for DNA Amplification and Multiplex Detection Fabricated by High-throughput R2R UV-NIL
Dr Barbara STADLOBER JOANNEUM RESEARCH, Weiz, Austria
Dr Barbara Stadlober is Principal Investigator at MATERIALS - the Institute for Surface Technologies and Photonics - of the JOANNEUM RESEARCH Forschungsgesellschaft mbH (JR) located in Austria. She studied Physics at the Karl-Franzens University in Graz and received a PhD from the Technical University in Munich-Garching. In 1996 she started her career as part of the technology development team of Siemens Halbleiter AG (later Infineon Technologies Austria) in Villach. She joined JR in 2002, where she started a research group dedicated to organic and printed electronics as well as large area micro/nanopatterning. Currently, Dr. Stadlober is head of the research group "Hybrid Electronics and Patterning". Her areas of interest range from organic thin-film transistors over printed piezoelectric sensors and nanogenerators to R2R UV-nanoimprinting for bionic, microoptical and microfluidic functional films. She authored more than 100 peer-reviewed publications and appears as inventor of more than 70 patents.
17:00
OC13 - Digital Light Processing Based 3D-Printed Microchip Electrophoresis Device with Integrated Electrochemical Detection
(YS)
Mrs Brenda Maria DE CASTRO COSTA UNICAMP, Campinas, Brazil
Mrs Brenda Maria DE CASTRO COSTA
Brenda M. de Castro Costa is a Ph.D. candidate in analytical chemistry enrolled in two partner institutions, the University of Campinas (Brazil) and Chimie ParisTech (France). Expertize in electrically driven techniques currently focused on miniaturizing these systems using 3D printing technology. Seeks to use first-class production design and process skills to push forward manufacturing excellence of innovative microfluidic devices for health and life sciences.
17:20
OC14 - Fabrication of Large-Scale 3D Scaffolds
(YS)
Ing Alejandro MADRID SÁNCHEZ VRIJE UNIVERSITEIT BRUSSEL, Brussel, Belgium
Ing Alejandro MADRID SÁNCHEZ
MSc. Alejandro Madrid Sánchez is a PhD candidate of the Brussels Photonics B-PHOT at VUB. He received his BSc degree in engineering physics (2015) and MSc degree in Applied Physics (2017) at EAFIT University, a period at which he strengthen his knowledge and experience in laser optical systems, optical system design and experimental skills. In 2018, he joined the team of Prof. Dr. Heidi Ottevaere at VUB where he is involved in multidisciplinary research in the fields of freeform optical design, micro-stereolithography, fluorescence microscopy and scaffold fabrication for burn wound dressings. His current research is focused on the design of laser optical systems to boost the fabrication of large-scale scaffolds with micrometre features.
Contact links
https://b-phot.org/team/alejandro-madrid
https://www.linkedin.com/in/alejandro-madrid-sanchez-0928a/
19:30
Young Scientists' Event
Tuesday July 5, 2022
Session 6 - Joint Session: Pharma and Biopharma Applications
Session Chair
Dr Anne-Catherine SERVAIS UNIVERSITY OF LIÈGE, Liege, Belgium
Dr Anne-Catherine SERVAIS
Anne-Catherine Servais obtained her PhD degree in Pharmaceutical Sciences at the University of Liege on chiral separation in nonaqueous capillary electrophoresis in 2005. During her postdoctoral research, she joined in 2008 the group of Professor de Jong (Department of Biomedical Analysis, Utrecht University) to study the coupling of nonaqueous capillary electrophoresis to mass spectrometry. Currently, she is Associate Professor at the Laboratory for the Analysis of Medicines (University of Liege) directed by Professor Fillet. She performs research in the development of innovative separation methods using miniaturized techniques for the analysis of biomarkers (metabolites, peptides and proteins), biopharmaceuticals including biological entities (virus-like particles) but also for the study of their molecular interactions. She is a (co)author of more than 80 peer-reviewed papers, with an H-index (Scopus) of 26.
09:00
KL07 - Characterization of Lipid Nanoparticles for mRNA Vaccines by Taylor Dispersion Analysis and Capillary Electrophoresis
Prof. Hervé COTTET UNIVERSITY OF MONTPELLIER, Montpellier, France
Prof. Hervé COTTET
Hervé Cottet (48) is full professor at the Max Mousseron Biomolecules Institute (IBMM) in Montpellier (France). Since 2012, he is the head of a Research Department (~15 permanent researchers) at the IBMM. His research work concentrates at the interface between separation sciences, pharmaceutical sciences, physical chemistry and polymers. He is developing CE methodologies and Taylor Dispersion Analysis (TDA) for the characterization of biopharmaceuticals (including vaccines), (bio)polymers, polyelectrolytes, drug delivery systems, dendrimers, nanoparticles, colloids and bacteria. He is both interested in fundamentals (mobility modeling, electrophoretic behavior) and practical (or industrial) applications of CE and TDA. Graduated from the Ecole Supérieure de Physique et Chimie Industrielles de Paris (ESPCI), he completed his PhD in analytical chemistry in 1999 at the Ecole Nationale Supérieure de Chimie de Paris (ENSCP- PSL, France) on Capillary Electrophoresis (CE). After a post-doc at the Technical University of Eindhoven (the Netherlands), he joined the University of Montpellier in 2000. He has co-authored more than 130 scientific articles dealing with CE and/or TDA.
09:30
OC15 - Exploiting Diverse Glycosylation Strategies for Optimized Glycoconjugated Vaccines
Dr Sara TENGATTINI UNIVERSITY OF PAVIA, Pavia, Italy
Dr Sara TENGATTINI
Sara Tengattini graduated in Pharmaceutical Chemistry and Technology at the University of Pavia, Italy. Then, she obtained her PhD discussing a thesis entailed “Development of innovative analytical methods for the characterization of potential neo-glycovaccines against tuberculosis”. Currently she is a researcher at the Department of Drug Sciences of the University of Pavia. Her research activities are mainly related to the development of analytical methodologies for the characterization of therapeutic proteins, with particular regards to monoclonal antibodies and glycoconjugate vaccines.
09:50
OC16- Chip-Sized Cell Gene Modification System for Integration into Modular Microfluidics
Dr Hashim ALHMOUD BILKENT UNIVERSITY, Ankara, Turkey
Dr Hashim ALHMOUD
Hashim Alhmoud is an early career researcher and an EC Marie-Curie Actions Fellow at Bilkent University's Department of Mechancial Engineering, Turkey. In 2016, Hashim obtained his PhD from the University of South Australia where he developed novel nanoparticle drug delivery systems for cell therapy and tissue engineering. He took up his first post-doctoral appointment between the years of 2017 and 2020 at Monash University's Faculty of Pharmacy in Melbourne Australia, where he continued his work on nanoengineered interfaces for cell modification and nanoscale delivery vectors. While there, he published over 10 peer-reviewed journal articles and participated in several industry-driven projects. He later joined Bilkent University and the National Nanotechnology Research Center in Turkey as a Marie-Curie Actions Fellow in 2021. His current research focuses on developing effective microfluidic modules for cell probing and modification with single-cell precision.
10:10
OC17 - Absolute Quantification and Structural Characterization of Infliximab in Human Serum Using Capillary Electrophoresis Hyphenated to Tandem Mass Spectrometry
(YS)
Ms Tessa REINERT UNIVERSITY OF STRASBOURG, Strasbourg, France
Ms Tessa REINERT
Tessa Reinert graduated in analytical chemistry at the University of Strasbourg in 2020. She is currently a 2nd year PhD student in co-direction between the Laboratory of Mass Spectrometry of Interactions and Systems (LSMIS) in Strasbourg and the Chemical and Biological Technologies for Health Unit (UTCBS) in Paris. Her PhD mainly focuses on the development of an analytical method for monoclonal antibody characterization and quantification.
10:30
Coffee break & Exhibition
11:00
OC18 - From Intact to Bottom-Up: Multidimensional Platform for Comprehensive Characterization of Monoclonal Antibodies in Crude Broths and Formulations from a Single Injection
(YS)
Mrs Arta SADIGHI VRIJE UNIVERSITEIT AMSTERDAM , Amsterdam, The Netherlands
Mrs Arta SADIGHI
Im doing my Ph.D. in the Netherlands in the group of Govert Somsen and Anouk Rijs where I focus on the hyphenation of different analytical techniques for the characterization of proteins. These include monoclonal antibodies (mAbs) and proteins that cause neurological diseases. Different online platforms are created to provide in-depth information on structural heterogeneity, post-translational modifications, and aggregation that may affect the activity, function, and stability of proteins.
11:20
OC19 -In-Vitro Drug-Induced Liver Injury Monitoring Using Raman Spectroscopy
(YS)
Ms Margot VANDERMOTTEN VRIJE UNIVERSITEIT BRUSSEL, Elsene, Belgium
Ms Margot VANDERMOTTEN
Margot Vandermotten is a PhD student at Brussels Photonics, VUB. She obtained her Bachelor’s degree in Electromechanical Engineering in 2019 and her Master’s degree in Biomedical Engineering in 2021 both from the Vrije Universiteit Brussel (VUB). Her research currently focuses on the use of optical detection techniques to identify the presence of Drug-Induced Liver Injuries (DILI) in liver in-vitro models
11:40
OC20 - All-Integrated Droplet Microfluidics Station for High-Throughput Single Cell Screening and Sorting
Dr Stéphanie VAN LOO LIVEDROP, Liege, Belgium
Dr Stéphanie VAN LOO
Graduated biomedical engineer from University of Liège in 2010, Stéphanie van Loo did a PhD thesis in the Microfluidics lab of the Aerospace and Mechanical Engineering department of the University of Liège from 2013 to 2017, entitled Droplet microfluidic for single-cell manipulation, under the supervision of Prof Tristan Gilet. During her PhD, she set up an entire droplet microfluidics set-up from scratch, starting from the design and fabrication of microfluidic chips. She collaborated with several biologists.
After her PhD, she wanted to make this fascinating technology available to all biologists, so she obtained funding from the Walloon Region to create a spin-off company whose objective would be to develop and commercialize droplet microfluidics instruments for biologists. She also worked as post-doc in the Unit of Animal Genomics of the GIGA research center of the University of Liège, during which she applied her technology to fundamental genomics research area.
She created the company LiveDrop in April 2022 to market the ModaFlow instrument.
Session Chair
Prof. Jeroen LAMMERTYN KULEUVEN, Leuven, Belgium
Prof. Jeroen LAMMERTYN
Jeroen Lammertyn is Full Professor at the Faculty of Bioscience engineering and head of MeBioS Division of the Biosystems Department at KU Leuven. He founded the MeBioS-Biosensors group in 2005, which currently counts 35 researchers. The lab focuses its research on the development of novel bio-molecular detection concepts and miniaturized analysis systems. He is (co)author of >250 peer reviewed research papers (h-index = 62, 14430 citations, average impact factor of 10 best publications = 15.9) and over 150 conference papers and book chapters. He was/is Technical Program Committee member of the 3 most important and largest conferences in the field of lab-on-a-chip technology (MEMS, MicroTAS and Transducers) and he is often invited to give lectures and keynote talks. He has established many research collaborations at the national and international level (e.g., 8 EU-projects). This has resulted in an accumulated project funding of over 30 M€ (>35 (inter)national projects funded by KUL, FWO, IWT, VLK, H2020, Bill and Melinda Gates Foundation, etc). Jeroen is co-inventor of 12 patent applications and founder of a spin-off company on fiber-optic biosensor (FOx Biosystems). During his career, he was a laureate of >10 awards (e.g. Quetelet Prize in Biostatistics, BiR&D Award 2014 for most original multidisciplinary PhD with high industrial valorization potential, …). Jeroen Lammertyn is involved in teaching 7 courses in the B.Sc. and M.Sc. programs of Bioscience Engineering and the Master in Nanoscience and Nanotechnology at the KU Leuven.
Session 8 - Microfluidics: from Droplets Towards Single Cells
Session 7 - Intact and Native Protein Analysis
Session Chair
Prof. Govert SOMSEN VU UNIVERSITY AMSTERDAM, Amsterdam, The Netherlands
Prof. Govert SOMSEN
Govert Somsen is full professor of Biomolecular Analysis/Analytical Chemistry at the Vrije Universiteit Amsterdam, The Netherlands. He obtained his doctorate in Amsterdam, and subsequently was assistant and associate professor at the University of Groningen and Utrecht University in The Netherlands. His main expertise is on hyphenated concepts in separation science directed to the characterization of (bio)polymers and (bio)active compounds. His group made significant contributions to the development, optimization and application of coupled analytical techniques combining selective liquid-phase separations with mass spectrometry, optical spectroscopy and bioactivity assays. He is (co-)author of over 200 papers in these fields, and editor of Journal of Chromatography B.
14:30
KL08 - Native CZE-MS of Proteins and Protein Complexes
Dr Kevin JOOSS NORTHWESTERN UNIVERSITY, Evanston, United States
Dr Kevin JOOSS
Kevin Jooß obtained his B.Sc. in Chemistry and M.Sc. in Analytical and Bioanalytical Chemistry from Aalen University in 2013 and 2014, respectively. He joined the research group of Prof. Christian Neusüß (Aalen University, Germany) and earned his Ph.D. in collaboration with the Technical University of Munich in 2019 developing multidimensional electromigrative separation approaches coupled to mass spectrometry. Afterwards, Dr. Jooß moved to Northwestern University (Evanston, IL, USA) as a postdoctoral fellow joining the lab of Prof. Neil Kelleher driving capillary electrophoresis-centric techniques in the context of denatured and native top-down proteomics. His interests include, amongst others, exploring the characteristics of protein separation under native conditions, nucleosome characterization in the context of epigenetic research, and promoting adaption of CE for top-down applications.
15:00
OC21 - Imaged Capillary Isoelectric Focusing Combined with MS And Bioactivity Detection for Characterisation of Snake Venoms
(YS)
Ing Mari-Anne ASSELER VRIJE UNIVERSITEIT AMSTERDAM, Amsterdam, The Netherlands
Ing Mari-Anne ASSELER
Mari-Anne Elles Asseler is from the Netherlands. Even though the Netherlands only has three native snake species, of which one is venomous. She has had the opportunity to research several venomous snake species from around the world. Her research involves looking at the native protein structures, using imaged capillary isoelectric focusing (iCIEF) in combination with bioactivity assays and MS for the analysis of crude snake venoms.
15:20
OC22 - Optimizing Intact Protein Separation Efficiency Using Capillary Electrophoresis
(YS)
Ms Laura DHELLEMMES UNIVERSITY OF MONTPELLIER, Montpellier, France
Ms Laura DHELLEMMES
Laura Dhellemmes received her Master of Engineering degree from ENSIACET, Toulouse in 2020. She is currently investigating SMIL coatings used in CE as a PhD student at IBMM, Montpellier, France, in the context of a ANR-PRCI project in collaboration with Prof. Christian Neusüß and Prof. Norbert Schaschke from the University of Aalen, Germany.
Session 8 - Microfluidics: from Droplets Towards Single Cells
Session Chair
Prof. Tristan GILET UNIVERSITY OF LIÈGE, Liège, Belgium
14:30
KL09 - Novel Microfluidic Platform for B-cell Screening and Retrieval: A Case Study on Anti-SARS-CoV-2 Monoclonal Antibody Discovery
Prof. Jeroen LAMMERTYN KULEUVEN, Leuven, Belgium
Prof. Jeroen LAMMERTYN
Jeroen Lammertyn is Full Professor at the Faculty of Bioscience engineering and head of MeBioS Division of the Biosystems Department at KU Leuven. He founded the MeBioS-Biosensors group in 2005, which currently counts 35 researchers. The lab focuses its research on the development of novel bio-molecular detection concepts and miniaturized analysis systems. He is (co)author of >250 peer reviewed research papers (h-index = 62, 14430 citations, average impact factor of 10 best publications = 15.9) and over 150 conference papers and book chapters. He was/is Technical Program Committee member of the 3 most important and largest conferences in the field of lab-on-a-chip technology (MEMS, MicroTAS and Transducers) and he is often invited to give lectures and keynote talks. He has established many research collaborations at the national and international level (e.g., 8 EU-projects). This has resulted in an accumulated project funding of over 30 M€ (>35 (inter)national projects funded by KUL, FWO, IWT, VLK, H2020, Bill and Melinda Gates Foundation, etc). Jeroen is co-inventor of 12 patent applications and founder of a spin-off company on fiber-optic biosensor (FOx Biosystems). During his career, he was a laureate of >10 awards (e.g. Quetelet Prize in Biostatistics, BiR&D Award 2014 for most original multidisciplinary PhD with high industrial valorization potential, …). Jeroen Lammertyn is involved in teaching 7 courses in the B.Sc. and M.Sc. programs of Bioscience Engineering and the Master in Nanoscience and Nanotechnology at the KU Leuven.
15:00
OC23 - Highly Accurate and Flexible Serial Picoinjection in Droplet Microfluidics
(YS)
Ing Jolien BREUKERS KU LEUVEN, Heverlee, Belgium
Ing Jolien BREUKERS
Jolien Breukers received a Master of Science degree in Bioscience Engineering at KU Leuven, Belgium, in 2017. Afterwards, she joined the Biosensors group at the Biosystems department of KU Leuven to pursue a PhD. In her research, she is developing novel microfluidic technologies for single-cell analysis, for which she mostly focuses on droplet microfluidics, continuous microfluidics and microwell array technologies.
15:20
OC24 - Microfluidic Droplet Instrumental and Methodological Development for Glycan Sample Processing Towards CDG Diagnostic Application
(YS)
Mr Théo LIÉNARD-MAYOR INSTITUT GALIEN PARIS-SUD, Châtenay-Malabry, France
Mr Théo LIÉNARD-MAYOR
Théo Liénard obtained his Master’s degree in fundamental physics from Université Paris-Saclay in 2018, with a specialization in microfluidics from Institut Pierre Gilles de Gennes. He is currently a 3rd year PhD student at Institut Galien Paris-Saclay in Myriam Taverna’s team, working on microfluidic solutions for both sample treatment and analysis of glycans by capillary electrophoresis with laser induced fluorescence detection (CE-LiF) for diagnosis of congenital disorders of glycosylation (CDGs).
Prize session - Sciex Innovation Award
Session Chair
Prof. Vincent REMCHO OREGON STATE UNIVERSITY, Corvallis, OR, 97331, United States
15:45
BA01 - Maturation of Microfluidics in an Era Where Real-world Problems Demand a Solution
Prof. James LANDERS UNIVERSITY OF VIRGINIA, VA, United States
Prof. James LANDERS
James Landers is a Jefferson Scholars Faculty Fellow and Commonwealth Professor of Chemistry, Professor of Mechanical Engineering, and an Associate Professor of Pathology at the University of Virginia. After obtaining degrees in Biochemistry from the University of Guelph (Canada), he did postdoctoral fellowships in Toxicology at the Hospital for Sick Children, in Endocrine Dysfunction at the University of Toronto School of Medicine and, in Steroid Hormone Cancers as a Canadian Medical Research Council Fellow at the Mayo Clinic. He created the Clinical Capillary Electrophoresis Facility in Laboratory Medicine at Mayo Clinic, where his work on microfluidic systems began, launched his academic career at the University of Pittsburgh, and then ramped up his program at the University of Virginia (UVA) where the sole focus was on developing microscale analytical technology. His UVA research team developed and demonstrated the first fully-integrated microfluidic system for sample-to-result genetic analysis, and this led to efforts with his start-up collaboration with Lockheed Martin developing ‘Rapid DNA’ systems for swab-to-STR profiling, and with the National Institutes of Health developing a 25-min point-of-need qPCR test for SARS-CoV-2. He has published more than 265 papers and serves as the CoEditor-in-Chief for the journal Analytica Chimica Acta.
17:00
Walking City Tour (1 hour)
19:30
Banquet
Wednesday July 6, 2022
09:00
Start of parallel sessions
Session 9 - Biomarkers for Precision Medicines
Session 10 - Point-of-Care Devices / from Lab-on-Chip Systems Towards Applications
Session 9 - Biomarkers for Precision Medicines
Session Chair
Prof. Serge RUDAZ UNIVERSITY OF GENEVA, Geneva, Switzerland
09:00
KL10 - Translating Brain Biomarkers Discovery to Clinical Practice
Prof. Jean-Charles SANCHEZ UNIVERSITY OF GENEVA, Genève, Switzerland
Prof. Jean-Charles SANCHEZ
Jean-Charles Sanchez (Associate Professor) has been working since 1989 in the field of proteomics and diagnostic biomarker discovery. He obtained his Ph.D. in Biochemistry at the Buckingham University (UK) in the field of proteomics and diabetes. Since 1995, he has been the head of the Translational Biomarker Group at the Geneva University, Swizerland and director of the Proteomics Core Facility of the Faculty of Medicine. He is the founder of the Swiss Proteomics Society (SPS), the European Proteomics Association (EuPA) and the Centre of Biomarkers Translation (CITB). He is also the founder of ABCDx SA, a clinical stage brain biomarker start-up. The activities in his research group cover the discovery of biomarkers associated to brain damage disorders such as stroke, traumatic brain injury, Parkinson disease and brain aneurism. Jean-Charles Sanchez is the author or co-author of more than 240 papers in refereed journals as well as more than 40 patents.
09:30
OC25 - Solid Phase Extraction - Mass Spectrometry Monitoring of Glucose-Regulating Hormones from Human Islets of Langerhans
Prof. Michael ROPER FLORIDA STATE UNIVERSITY, Tallahassee, United States
Prof. Michael ROPER
Michael Roper obtained his PhD from Prof. Robert T. Kennedy in 2003 and then performed postdoctoral research with Prof. James P. Landers. Since joining the Department of Chemistry and Biochemistry and the Program in Molecular Biophysics at Florida State University in 2006, the Roper research group has developed powerful analytical systems for the quantitative measure-ment of small molecules and peptides secreted from cellular tissues with high temporal resolution. In particular, his group has examined the endocrine portion of the pancreas, islets of Langerhans, which are responsible for controlling blood glucose levels through the release of hormone pep-tides. Dr. Roper has received the 2013 American Chemical Society Division of Analytical Chemis-try’s Young Investigator Award in Separation Science and the 2018 Mid-Career Award by the American Electrophoresis Society.
09:50
OC26 - Isobaric Derivatization of Endothelial Cell Lysates for 6-Plex Thiol Metabolomics by LC-MS/MS
(YS)
Mr Michael ARMBRUSTER SAINT LOUIS UNIVERSITY, Ballwin, United States
Mr Michael ARMBRUSTER
Michael is a 5th year doctoral student working in the Department of Chemistry at Saint Louis University under the direction of Dr. Jim Edwards. His research focuses on isotope derivatization of metabolites to improve mass spectrometry throughput by multiplexing.
10:10
OC27 - Towards Single Cell Glycomics
Dr Guinevere LAGEVEEN-KAMMEIJER LEIDEN UNIVERSITY MEDICAL CENTER, Leiden, The Netherlands
Dr Guinevere LAGEVEEN-KAMMEIJER
Guinevere S.M. Lageveen-Kammeijer is a senior scientist at the Glyco(proteo)mics group at the Center for Proteomics. She defended her thesis: “Unravelling the Sugar-Coating of Prostate-Specific Antigen – Method Development and its Application to Prostate Cancer Research” in 2019 and established her own research line on identifying potential biomarkers of prostate cancer, where she particularly concentrates on changes in post-translational modifications on prostate-specific antigen and other tumor antigens.
Dr. Lageveen-Kammeijer is an internationally recognized expert in the characterization and identification of potential glyco(proteo)mic biomarkers for several diseases (e.g. cancer and inflammation) in various biofluids with the final aim to translate her findings into the clinics. Moreover, she has extensive experience in improving glyco(proteo)mic methods for various analytical platforms which are mass spectrometry based. Particularly using capillary electrophoresis hyphenated with mass spectrometry to gain in-depth knowledge at high sensitivity.
Session 10 - Point-of-Care Devices / from Lab-on-Chip Systems Towards Applications
Session Chair
Prof. Heidi OTTEVAERE VRIJE UNIVERSITEIT BRUSSEL (VUB), Brussels, Belgium
09:00
KL11 - A Journey on Point of Care Devices: from Concept, Regulation, Classification up to Real and Potential Applications
Dr Laura PASQUARDINI INDIVENIRE SRL, Trento, Italy
Dr Laura PASQUARDINI
Laura Pasquardini graduated in Physics at the University of Trento in 2000. Since 2021, she is habilitated as Associate Professor in Applied Physics from MIUR, Italy. She worked as a researcher at the Bruno Kessler Foundation in Trento and the University of Trento, dealing with the development of micro and nanodevices and biosensors for genomics and proteomics. Her know-how focused on the development and characterization of biointerfaces. Following highly multidisciplinary projects, her expertise has been broadened also in different fields such as chemical synthesis of materials, electronic engineering, medicine and agro-food. She is author of more than 60 articles in peer-reviewed scientific journals. Since 2018, she co-founded Indivenire srl, an innovative startup aimed to help small and medium enterprises in their research and development activities but also supporting university departments in specific research activities.
09:30
OC28 - Self-Powered Lab-On-A-Chip Technology for Automated Sample Pre-Processing of Lateral Flow Immunoassays
(YS)
Mr Dries VLOEMANS KU LEUVEN , Heverlee, Belgium
Mr Dries VLOEMANS
Dries Vloemans is a postdoctoral researcher in the biosensors group of the University of Leuven (Belgium). During his PhD, he specialized in developing novel self-powered lab-on-a-chip microfluidic technologies for microsampling and point-of-care in vitro diagnostic applications. Now his activities are focused on the valorization of these technologies for real market applications.
09:50
OC29 - Lab-On-A-Disc Platform for Pathogen Detection in Stool: Effect of Inertial Forces and Walls on the Species Migration
Dr Vyacheslav MISKO VRIJE UNIVERSITET BRUSSEL (VUB), Brussels, Belgium
Dr Vyacheslav MISKO
After receiving PhD in physics, Dr. V. R. Misko studied various phenomena in mesoscopic physics first at the University of Antwerp, Belgium. Then he worked as a research fellow at the Research Center Jülich in Germany, at the University of Michigan in the US and at the Institute of Physical and Chemical Research, RIKEN, in Japan, where he studied dynamics of complex systems, quasicrystals, diffusion and ratcheting, and particle separation methods. Later he became a laureate of the “Odysseus” Program of the Flemish Government intended to develop new research lines in Flanders. The research of Dr. Misko includes dynamics of complex systems and active soft matter: diffusion in low-dimensional systems, self-organization, active diffusion of self-propelled Janus particles in confined and crowded microfluidic environments, particle separation methods and biomedical applications such as biosensing, targeted drug delivery, selection and enhancement of sperm motility, formation of bio-condensates and other topics. At the Flow Group at the Department of Chemical Engineering at the Vrije Universiteit Brussel, VUB, he is active in dynamics and separation techniques of driven particles and active micro-motors in microfluidics.
10:10
OC30 - Integration of Hydrogels into Microfluidic Devices with Porous Membranes and Demonstration Gel Electrophoretic DNA Quantification
(YS)
Ms Shadi SHAHRIARI MCMASTER UNIVERSITY, Hamilton, Canada
Ms Shadi SHAHRIARI
Shadi Shahriari is a direct PhD student in Mechanical Engineering at McMaster University. She is working on developing simple and low-cost microfluidic devices for rapid detection of Sepsis. She has obtained her bachelor's degree in Chemical Engineering from Sharif University of Technology in Iran.
10:30
Coffee break & Exhibition
11:00
Start of parallel sessions
Session 11 - Microscale Separations for –Omics Sciences
Session 12 - Advances in Microscale CE and LC Separations
Session 11 - Microscale Separations for –Omics Sciences
Session Chair
Dr Rawi RAMAUTAR LEIDEN UNIVERSITY, Leiden, The Netherlands
11:00
KL12 - CE-MS and LC-MS for the Untargeted Metabolomics Investigation of Cardiac Cells Undergoing Oxidative Stress and Other Diseases Simulations
Prof. Ana Valéria COLNAGHI SIMIONATO UNIVERSITY OF CAMPINAS, Campinas SP, Brazil
Prof. Ana Valéria COLNAGHI SIMIONATO
Associate professor at Department of Analytical Chemistry - Institute of Chemistry - State University of Campinas since 2008 and member of the National Institute of Science and Technology for Bioanalytics (INCTBio). Under graduated in Chemistry at Federal University of São Carlos, obtained the master degree at Institute of Chemistry at São Carlos – University of São Paulo (IQSC-USP), and doctorate degree at IQSC - USP. Worked as a visiting fellow with Dr. Paul Vouros at Northeastern University. Also worked as a visiting fellow with Dr Alejandro Cifuentes at Consejo Superior de Investigaciones Cientificas. She did a post-doctorate at Institute of Chemistry – University of São Paulo. Valéria main skills are separation techniques (capillary electrophoresis, liquid chromatography and gas chromatography) and mass spectrometry mainly dedicated to metabolomics aiming the investigation of human diseases biomarkers and general clinical applications. She has an h index 13 and supervised over forty undergraduate and graduate fellows.
11:30
OC31 - Going Micro with your Regular LC: The Plumber Will Make the Difference
Dr Víctor GONZÁLEZ-RUIZ UNIVERSITY OF GENEVA (SWITZERLAND), Geneva, Switzerland
Dr Víctor GONZÁLEZ-RUIZ
Vı́ctor González-Ruiz is a pharmacist (2008) and holds a M.S. in Pharmaceutical R&D (2009). He got a Ph.D. in Analytical Chemistry (2014) from the Complutense University of Madrid, developing LC- and fluorescence-based analytical techniques to study antitumor drugs and their mechanisms of action. In 2015 he joined the Analytical Sciences lab at the School of Pharmaceutical Sciences, University of Geneva, where he currently works as a research associate. His main research interest is the development of toxicology-oriented analytical (mainly CE-MS and LC-MS) and data handling strategies for metabolomics, in collaboration with the Swiss Center for Applied Human Toxicology.
11:50
OC32 - Single-Shot Proteomics Using Next Generation Pillar Array Column Prototypes with FAIMS and Orbitrap Based Mass Spectrometry
Dr Robert VAN LING THERMO FISHER SCIENTIFIC, Ghent , Belgium
Session 12 - Advances in Microscale CE and LC Separations
Session Chair
Prof. Myriam TAVERNA UNIVERSITY PARIS SACLAY, CHATENAY MALABRY, France
11:00
KL13 - The Organic Capillary Electrophoresis Analysis System (OCEANS) for Future Life Detection Missions
Dr María Fernanda MORA NASA JET PROPULSION LABORATORY, Pasadena, United States
Dr María Fernanda MORA
Dr María Fernanda Mora was born and raised in Cordoba, Argentina. She began her studies at the National University of Cordoba, Argentina, where she obtained a Bachelor degree in Chemistry. She later received her Ph.D. from in Chemistry from the University of Texas at San Antonio. She is a Technologist in the Chemical Analysis and Life Detection Group at the NASA Jet Propulsion Laboratory. Dr. Mora’s research focuses on the development of instruments for chemical analysis in situ in the context of astrobiology and planetary science. Her current work involves developing methodologies for extraction of organic compounds and analysis by capillary electrophoresis coupled to mass spectrometry, laser-induced fluorescence, and contactless conductivity detection.
11:30
OC33 - Characterization of a Novel Nanoflow Sheath Liquid CE-MS Interface: Analytical Properties, Flow Rates and Applications
Prof. Christian NEUSÜß AALEN UNIVERSITY, Aalen, Germany
11:50
OC34 - Sensitive and Valve-Free Targeted Bottom-Up Analysis of Protein Biomarkers by On-Line Aptamer Affinity Solid-Phase Extraction-Immobilized Enzyme Microreactor Capillary Electrophoresis-Mass Spectrometry
Dr Roger PERO-GASCON UNIVERSITAT DE BARCELONA, Barcelona, Spain
Dr Roger PERO-GASCON
Dr Roger Pero-Gascon obtained his PhD in analytical chemistry from the University of Barcelona, Spain, in 2020. He has extensively investigated on-line solid-phase extraction capillary electrophoresis-mass spectrometry using different affinity sorbents (immunoaffinity, aptamer affinity, immobilized metal affinity) for the analysis of protein and microRNA biomarkers of chronic diseases. In 2019, he did a stay in Hochschule Aalen, Germany, and successfully developed a novel on-line setup with a nanoliter valve. Recently, he joined Ghent University in Belgium as a post-doc to work on the FLEXIGUT exposome project, which aims to investigate the life-course impact of environmental and dietary factors on the development of chronic low-grade gut inflammation through a multi-omics approach.
12:10
Lunch & Exhibition
12:40
Lunch Seminar - Agilent
CE as a Tool for the Quality Control of Vaccines and CE-MS for Proteomics Analysis in Multiple Myeloma Disease
Dr Laura PASQUARDINI INDIVENIRE SRL, Trento, Italy
Dr Laura PASQUARDINI
Laura Pasquardini graduated in Physics at the University of Trento in 2000. Since 2021, she is habilitated as Associate Professor in Applied Physics from MIUR, Italy. She worked as a researcher at the Bruno Kessler Foundation in Trento and the University of Trento, dealing with the development of micro and nanodevices and biosensors for genomics and proteomics. Her know-how focused on the development and characterization of biointerfaces. Following highly multidisciplinary projects, her expertise has been broadened also in different fields such as chemical synthesis of materials, electronic engineering, medicine and agro-food. She is author of more than 60 articles in peer-reviewed scientific journals. Since 2018, she co-founded Indivenire srl, an innovative startup aimed to help small and medium enterprises in their research and development activities but also supporting university departments in specific research activities.
Prof. Christian NEUSÜß AALEN UNIVERSITY, Aalen, Germany
Dr Luc SCHERES SURFIX, Wageningen, The Netherlands
Dr Luc SCHERES
Luc is the CTO of Surfix. In 2005 he received his MSc degree in Chemistry and Physics at Utrecht University. Subsequently Luc moved to Wageningen University and obtained his PhD degree (with highest honours) in 2010. After a short post-doc at Eindhoven University Luc founded Surfix in 2011.
13:50
KL15 - Affinity-based Monolith: from TCM Screening to mAbs Analysis
Prof. Zhengjin JIANG JINAN UNIVERSITY, Guangzhou, China
Prof. Zhengjin JIANG
Dr Zhengjin Jiang is a full professor at the College of Pharmacy, Jinan University, Guangzhou, China. He received his PhD degree in the Institute of Elemento-Organic Chemistry, Nankai University in 2001. Afterwards, he worked for one year in Unimicro (Tianjin) Technologies, Inc, followed as a postdoctoral researcher or research fellow in University of Tuebingen in Germany, King‘s College London, Pfizer (Sandwich, UK) Research Centre, Novartis (Horsham, UK) Research Centre, respectively. His research interest is in the field of developing novel separation methods and equipment for pharmaceutical analysis, particularly integrated natural product screening platform, Dynamic tracking platform for in vivo PTM changes of monoclonal antibody etc. He served as the editor of Journal of Pharmaceutical and Biomedical Analysis, the associated editor of Frontiers in Analytical Science (Pharmaceutical analysis) as well as the chair of the 27th International Symposium on Pharmaceutical and Biomedical Analysis in 2016. Current, he is also listed in the editorial advisory board of Journal of Chromatography A, Journal of Pharmaceutical and Biomedical Analysis, Current Analytical Chemistry, Chinese Journal of Pharmaceutical Analysis etc.
14:20
OC35 - Immobilization of GPR17 Receptor for Surface Plasmon Resonance Binding Experiments
Prof. Enrica CALLERI UNIVERSITY OF PAVIA, Pavia, Italy
Prof. Enrica CALLERI
Prof. Enrica Calleri obtained her PhD in Chemistry and Pharmaceutical Technology at the University of Pavia, Italy. Prof. Enrica Calleri is now Associate Professor of Pharmaceutical Analysis at the same University.
Enrica Calleri is author of approximately 90 publications in peer-reviewed journals.
Enrica Calleri has a strong analytical background, mainly on the use of separation techniques for molecular recognition and drug discovery.
Her scientific interests have been focused on:
1. development of biochromatographic systems for binding studies and affinity selection of new potential drug candidates
2. development of bioreactors for biopharmaceutical characterization
3. development of bioreactor for the flow-synthesis of API
4. development of SPR methods
14:40
OC36 - Microfluidics Chips Fabrication: Cutting, Drilling, Engraving and Sealing of Various Designs Using Recent Laser Technologies
Ing Marc DÉCULTOT LASEA, Seraing, Belgium
Ing Marc DÉCULTOT
A graduate from the Telecom Physique Strasbourg in France in 2010, Marc Décultot worked during 5 years as researcher in optics laboratory of University of Liège in Belgium. In 2016, he joined the R&D department of Lasea in the Optical & Device Metrology Unit.
15:00
OC37 - Micro-Engineering Solutions to Accelerate the Development of Polymer Microfluidic Devices
Dr Denis VANDORMAEL SIRRIS, Seraing, Belgium
Dr Denis VANDORMAEL
Denis Vandormael obtained his BSc in physics (1994) and his PhD in science (1999) from the University of Liege (Belgium).
He specialized in micro-optics and micro-fabrication during his former professional activities at the Centre Spatial de Liège (Belgium).
In 2009 he joined SIRRIS, the Collective Research Centre for Belgian Technological Industry, where he is now in charge of the Micro Lab, a unit specialized in micro-engineering.
His expertise is mainly oriented towards project management, process and product development, in the context of R&D and industrial projects dealing with microfabrication for various sectors such as optics, mechanics and healthcare.
15:20
Coffee break & Exhibition
Session Chair
Prof. Marianne FILLET UNIVERSITY OF LIÈGE, Liege, Belgium
15:50
PL04 - Combining Multidimensional Measurements with Standards and Isotopologue Workflows to Detect, Identify and Validate Molecules in Omic Studies
Prof. Erin S. BAKER NC STATE UNIVERSITY, Raleigh, United States
Erin S. Baker received her Ph.D. from the University of California Santa Barbara under the instruction of Michael Bowers and spent 13 years at Pacific Northwest National Laboratory as a Postdoctoral Researcher and Senior Scientist in Richard Smith’s group. In 2018, Erin moved to Raleigh, North Carolina where she is an Associate Professor at North Carolina State University. To date, she has published over 140 peer-reviewed papers utilizing ion mobility spectrometry in conjunction with mass spectrometry (IMS-MS) to study both environmental and biological systems. Currently, the Baker research group utilizes advanced separations, multi-omic analyses and big data assessments to drive innovative mass spectrometry technologies, systems biology evaluations, novel software capabilities and connections between human health and the environment. For this work, Erin has received seven US patents, two R&D 100 Awards, been named to the Analytical Scientist 2019 Top 100 Power List, aided in the commercialization of the Agilent 6560 IMS-QTOF MS, and was a recipient of the 2016 ACS Rising Star Award for Top Midcareer Women Chemists.
16:40
MSB 2023 announcement
Prof. Michael ROPER FLORIDA STATE UNIVERSITY, Tallahassee, United States
Prof. Michael ROPER
Michael Roper obtained his PhD from Prof. Robert T. Kennedy in 2003 and then performed postdoctoral research with Prof. James P. Landers. Since joining the Department of Chemistry and Biochemistry and the Program in Molecular Biophysics at Florida State University in 2006, the Roper research group has developed powerful analytical systems for the quantitative measure-ment of small molecules and peptides secreted from cellular tissues with high temporal resolution. In particular, his group has examined the endocrine portion of the pancreas, islets of Langerhans, which are responsible for controlling blood glucose levels through the release of hormone pep-tides. Dr. Roper has received the 2013 American Chemical Society Division of Analytical Chemis-try’s Young Investigator Award in Separation Science and the 2018 Mid-Career Award by the American Electrophoresis Society.
16:45
Closing Ceremony
Prof. Heidi OTTEVAERE VRIJE UNIVERSITEIT BRUSSEL (VUB), Brussels, Belgium Prof. Marianne FILLET UNIVERSITY OF LIÈGE, Liege, Belgium