12th EFMC Short Course on Medicinal Chemistry

Modulation of Enzymes; Epigenetics and Beyond

 Oegstgeest (near Leiden), The Netherlands    April 24-27, 2016

Programme


18:00

Dinner

20:00

Opening

20:15

Basic Principles of Enzymology

Dr Laurie LEBRUN
CELGENE, San Diego, United States

07:30

Breakfast

08:30

Introduction

09:00

Protein Kinase Inhibitors

Dr Gerhard MÜLLER
MERCACHEM, Martinsried, Germany

10:30

Coffee Break

11:00

Epigenetic Target Families in Medicinal Chemistry

Prof. Paul BRENNAN
UNIVERSITY OF OXFORD, Oxford, United Kingdom

12:30

Lunch

13:30

BETting on Epigenetic Targets: From Phenotypic Discovery to First Time in Man

Dr Chun-wa CHUNG
GLAXOSMITHKLINE R&D, Stevenage, United Kingdom

15:00

Coffee Break

15:30

Hands on Tutorial - Case Study I: Development of a Kinase Inhibitor

Dr Leon VAN BERKOM
MERCACHEM-SYNCOM, Nijmegen, The Netherlands


Dr Toine VAN DEN BERGH
MERCACHEM-SYNCOM, Nijmegen, The Netherlands

18:00

Day End

07:30

Breakfast

08:30

Proteases as Drug Targets

Dr Holger SELLNER
NOVARTIS PHARMA AG, Basel, Switzerland

10:00

Coffee Break

10:30

Proteasome Inhibitors

Prof. Michael GROLL
TECHNISCHE UNIVERSITÄT MÜNCHEN, Garching, Germany

12:00

Lunch

13:00

Glycomimetics - an Underexplored Compound Class for Medicinal Chemistry

Prof. Dr Beat ERNST
UNIVERSITY OF BASEL, Basel, Switzerland

14:30

Coffee Break

15:00

Hands on Tutorial - Case Study II: Development of a HIV Medicine

Dr Stijn GREMMEN
MERCACHEM, Nijmegen, The Netherlands


Dr Harald ALBERS
MERCACHEM-SYNCOM, Nijmegen, The Netherlands

17:30

Day End

07:30

Breakfast

08:30

The PDE Family and Inhibitors

Dr Andrew BELL
IMPERIAL COLLEGE LONDON, London, United Kingdom

10:00

Coffee break

10:30

Fragment-Based Lead Generation

Prof. Iwan DE ESCH
VRIJE UNIVERSITEIT AMSTERDAM, Amsterdam, The Netherlands

12:30

Wrap-up and Lunch