Monday June 17, 2019 |
08:00 | Registration |
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09:10 | Opening |
Prof. Matthias D'HOOGHE (GHENT UNIVERSITY, Ghent, Belgium) |
| Session 1 |
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| Session Chair |
Prof. Christian STEVENS (UGENT, Ghent, Belgium) |
09:30 | Heterocycles as Key Features of New Starting Points for Drug Discovery (PL01) |
Dr Peter MEIER (NOVARTIS PHARMA AG, Basel, Switzerland) |
10:15 | Development of Enzyme Inhibitors and Multi-target-directed Ligands for Treating Neurodegenerative Diseases (IL01) |
Prof. Stanislav GOBEC (UNIVERSITY OF LJUBLJANA, Ljubljana, Slovenia) |
10:45 | Coffee break |
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| Session 2 |
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| Session Chair |
Prof. Till OPATZ (JOHANNES GUTENBERG-UNIVERSITY, Mainz, Germany) |
11:15 | Silil-Prins Cyclization: Towards the Synthesis of Medium Sized Heterocycles (OC01) |
Prof. Asuncion BARBERO (UNIVERSITY OF VALLADOLID, Valladolid, Spain) |
11:30 | Chiral Piperidines from Pyridines: the Meta-Substitution Challenge in Asymmetric Hydrogenation (OC02) |
Dr Paul ALSTERS (INNOSYN B.V., Geleen, The Netherlands) |
11:45 | Expanding the Chemical Space of Chiral Trifunctional Building Blocks by Stereoselective Synthesis from Natural Terpenes (IL02) |
Prof. Zsolt SZAKONYI (UNIVERSITY OF SZEGED, Szeged, Hungary) |
12:15 | Lunch |
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| Session 3 |
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| Session Chair |
Prof. Fawaz ALDABBAGH (KINGSTON UNIVERSITY, London, United Kingdom) |
13:30 | A Journey in Heteroaromatic Scaffolds as Protein Kinase Inhibitors (PL02) |
Prof. Pascale MOREAU (UNIVERSITY OF CLERMONT AUVERGNE, Aubière, France) |
14:15 | Bacterial Quinolones and Derivatives: New Drugs for Bad Bugs (IL03) |
Dr Thomas BOTTCHER (UNIVERSITY OF KONSTANZ, Konstanz, Germany) |
14:45 | Hydrogen Peroxide and Hydrohalic Acid-Mediated Synthesis of Ring-Fused Benzimidazolequinone Anti-Cancer Agents (OC03) |
Mr Darren CONBOY (KINGSTON UNIVERSITY LONDON, Kingston upon Thames, United Kingdom) |
15:00 | Coffee break |
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| Session 4 |
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| Session Chair |
Dr Bart ROMAN (GHENT UNIVERSITY, Ghent, Belgium) |
15:30 | Thionations Using a P4S10-Pyridine Complex (OC04) |
Ms Ngarita KINGI (VIRONOVA MEDICAL AB, Stockholm, Sweden) |
15:45 | First Solid-Phase Strategy for the Total Synthesis of Fengycin Derivatives, a Class of Cyclic Lipodepsipeptides (OC05) |
Dr Lidia FELIU (LIPPSO, UNIVERSITY OF GIRONA, Girona, Spain) |
16:00 | Design and Synthesis of New Nitrogen-Containing Heterocycles for the Treatment of Mechanical Allodynia (OC06) |
Ms Alexia VISSEQ (INSTITUT DE CHIMIE DE CLERMONT FERRAND, AUBIERE, France) |
16:15 | Poster Session |
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18:00 | Welcome Reception (Ghent City Hall) |
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Tuesday June 18, 2019 |
| Session 5 |
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| Session Chair |
Prof. Bert MAES (UNIVERSITY OF ANTWERP, Antwerp, Belgium) |
09:00 | Heterocycles To Control Immune Cell Function (PL03) |
Prof. David FAIRLIE (UNIVERSITY OF QUEENSLAND, Brisbane, Australia) |
09:45 | Vitamin B12 – an Intriguing Bioheterocycle (IL04) |
Prof. Dorota GRYKO (INSTITUTE OF ORGANIC CHEMISTRY PAS, Warsaw, Poland) |
10:15 | Hydroxylated Heterocycles as a Bioisosteric Tool to Modulate the Carboxylic Function (OC08) |
Dr Agnese Chiara PIPPIONE (UNIVERSITY OF TURIN, Torino, Italy) |
10:30 | Tweaking the Blebbistatin Scaffold Towards Better Pharmacological Tools (OC09) |
Dr Bart ROMAN (GHENT UNIVERSITY, Ghent, Belgium) |
10:45 | Coffee break |
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| Session 6 |
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| Session Chair |
Prof. Asuncion BARBERO (UNIVERSITY OF VALLADOLID, Valladolid, Spain) |
11:15 | The Magic of Wood and Light – New Concepts for Synthetic Chemistry (OC10) |
Prof. Till OPATZ (JOHANNES GUTENBERG-UNIVERSITY, Mainz, Germany) |
11:30 | Synthesis of Enantioenriched 3-Isobenzofuranones Using Chiral Organomagnesiates (OC11) |
Dr Sabrina TOUCHET (UNIVERSITÉ DE LORRAINE, Vandoeuvre-les-Nancy, France) |
11:45 | Functionalization of Aromatic Heterocycles Using Bases Derived from LiTMP (IL05) |
Prof. Florence MONGIN (UNIVERSITY OF RENNES, Rennes, France) |
12:15 | Lunch |
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| Session 7 |
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| Session Chair |
Prof. Stanislav GOBEC (UNIVERSITY OF LJUBLJANA, Ljubljana, Slovenia) |
13:30 | Synthesis of Heterocyles Using Visible Light Photocatalysis (PL04) |
Prof. Burkhard KÖNIG (UNIVERSITY OF REGENSBURG, Regensburg, Germany) |
14:15 | Leveraging Carbonylation and N-acyl imine Chemistry in Heterocycle Synthesis (IL06) |
Prof. Luke ODELL (UNIVERSITY OF UPPSALA, Uppsala, Sweden) |
14:45 | Structurally Simple Cytosine Peptidomimetics as Potent Cardioprotectors in Myocardial Ischemia (MI) Mouse Model: Design, Synthesis And Biological Evaluation (OC12) |
Dr Edward KORSHIN (BAR-ILAN UNIVERSITY, Ramat Gan, Israel) |
15:00 | Biradical Formation by Deprotonation in Conjugated 2-Amino/Imino Thiazole Derivatives (OC13) |
Prof. Francisco LOPEZ-CALAHORRA (UNIVERSITAT DE BARCELONA, Barcelona, Spain) |
16:00 | Excursion |
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Wednesday June 19, 2019 |
| Session 8 |
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| Session Chair |
Prof. Wim DE BORGGRAEVE (KU LEUVEN, Leuven, Belgium) |
09:00 | The Beautiful Simplicity of Rearrangements (PL05) |
Prof. Nuno MAULIDE (UNIVERSITY OF VIENNA, Vienna, Austria) |
09:45 | A journey with Saponins (IL07) |
Dr Martina LAHMANN (BANGOR UNIVERSITY, Wales, United Kingdom) |
10:15 | Small but Selective: Developing Chemical Probes for PKN/PRK2 (OC14) |
Dr Fiona SCOTT (SUSSEX DRUG DISCOVERY CENTRE, Falmer, United Kingdom) |
10:30 | Application of Tsunoda reagent to the convenient synthesis of drug-like pyrazoles (OC15) |
Dr Olivier LORTHIOIR (ASTRAZENECA, Cambridge, United Kingdom) |
10:45 | Coffee break |
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| Session 9 |
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| Session Chair |
Prof. Florence MONGIN (UNIVERSITY OF RENNES, Rennes, France) |
11:15 | The Phenanthridine PJ-34 Exclusively Eradicates Human cancer Cells (OC16) |
Prof. Malka COHEN-ARMON (TEL-AVIV UNIVERSITY, Tel-Aviv, Israel) |
11:30 | Synthesis and in vitro -Glucosidase Inhibitory Activity of Polyhydroxylated 2-Styrylchromones (OC17) |
Dr Clementina SANTOS (INSTITUTO POLITÉCNICO DE BRAGANÇA, Braganca, Portugal) |
11:45 | Heterocycles and Neglected Diseases: Still a Role for Total Synthesis (IL08) |
Prof. Adrian DOBBS (UNIVERSITY OF GREENWICH, Kent, United Kingdom) |
12:15 | Lunch |
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| Session 10 |
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| Session Chair |
Prof. Zsolt SZAKONYI (UNIVERSITY OF SZEGED, Szeged, Hungary) |
13:30 | Multiple Conjugation Reactions on Peptides and Oligonucleotides (PL06) |
Prof. Anna GRANDAS (UNIVERSITY OF BARCELONA, Barcelona, Spain) |
14:15 | Heterocycles as a Route to New Chemical Space for Drug Discovery (IL09) |
Prof. James BULL (IMPERIAL COLLEGE, London, United Kingdom) |
14:45 | 'Stretched' Analogs of Piperidine, Piperazine, and Morpholine: Advanced Building Blocks for Drug Discovery (OC18) |
Dr Ivan KONDRATOV (ENAMINE, Kyiv, Ukraine) |
15:00 | Coffee break |
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| Session 11 |
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| Session Chair |
Dr Thomas HEUGEBAERT (UGENT, Gent, Belgium) |
15:30 | Biologically Active Oxygen and Nitrogen Heterocyclic Compounds from Cycloaddition and Conjugate Addition Reactions On Chromones (OC19) |
Prof. Artur M.S. SILVA (UNIVERSITY OF AVEIRO, Aveiro, Portugal) |
15:45 | Combining Isocyanides with Carbon Dioxide for Heterocycle Synthesis (OC20) |
Mr Jeroen BOMON (UNIVERSITEIT ANTWERPEN, Antwerpen, Belgium) |
16:00 | Kolbe Anodic Decarboxylation as a Green Way to Access Pyrrolidinones (OC21) |
Ms Mathilde QUERTENMONT (UNIVERSITÉ CATHOLIQUE DE LOUVAIN, La Hulpe, Belgium) |
16:15 | Playing with Properties of Biologically Active Compounds: High-Throughput Conjugation of Drug-Like Molecules for Chemical Biology (OC22) |
Ms Sona KRAJCOVICOVA (PALACKY UNIVERSITY, Olomouc, Czech Republic) |
16:30 | Poster Session |
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19:00 | Symposium Banquet |
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Thursday June 20, 2019 |
| Session 12 |
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| Session Chair |
Prof. Sven MANGELINCKX (GHENT UNIVERSITY, Ghent, Belgium) |
10:00 | Heterocyclic Chemistry in Drug Development (PL07) |
Prof. Wim DE BORGGRAEVE (KU LEUVEN, Leuven, Belgium) |
10:45 | Biologically Active Azaheterocycles Containing a Ferrocene Moiety (IL10) |
Prof. Niko S. RADULOVIC (UNIVERSITY OF NIS, Nis, Serbia) |
11:15 | Regioselective C-H Arylation of Nitro Heterocycles and Further Transformation of Manipulable Nitro Group (OC23) |
Dr Viktor IAROSHENKO (POLISH ACADEMY OF SCIENCES, Lodz, Poland) |
11:30 | Towards DNA-Encoded Heterocycle Libraries - DNA-Compatible Povarov and Groebke Reactions by Micellar Broensted Acid Catalysis (OC24) |
Dr Andreas BRUNSCHWEIGER (TU DORTMUND, Dortmund, Germany) |
11:45 | Closing and Award ceremony |
Prof. Matthias D'HOOGHE (GHENT UNIVERSITY, Ghent, Belgium) |
12:00 | Lunch |
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