MST Drug Discovery Forum

   Partners

Sunday February 9, 2014
14:00Registration
14:30Sightseeing tour to Kloster Ettal
(including liquor tasting, visit of the famous church, dinner with typical Bavarian dishes)
Monday February 10, 2014
11:00Registration and welcome coffee
13:30Opening remarks
Speakers' presentations
14:00MicroScaleThermophoresis in Modern Drug Discovery Process
Dr Alexey RAK
(SANOFI AVENTIS, Vitry-sur-Seine, France)
14:30Eighty Targets in Four Years - Integrating MST in an Industrial Setting
Dr Ismail MOAREFI
(CRELUX GMBH, Martinsried, Germany)
15:00Fast and Quantitative Analysis of Aptamer-target Interactions Using MicroScale Thermophoresis
Dr Thomas SCHUBERT
(2BIND, Regensburg, Germany)
15:30Coffee break
Future Application Session
16:00MicroScale Thermophoresis: Interaction Analysis and Beyond
Dr Dennis BREITSPRECHER
(NANOTEMPER TECHNOLOGIES GMBH, Muenchen, Germany)
16:30Towards Novel Antivirals for Human Hepatitis B Virus Infections
Dr Neil FERGUSON
(UNIVERSITY COLLEGE DUBLIN, Dublin, Ireland)
17:00The Heat of the Moment: Using MST to Access Binding Thermodynamics
Dr Geoff HOLDGATE
(ASTRAZENECA, Macclesfield, United Kingdom)
17:30Poster session & informal get-together
19:00Conference dinner
Tuesday February 11, 2014
Fragment Screening Session
08:30The Use of Virtual Screening and DSF for the Rapid Identification of Fragments Active Against MEK1
Dr Alexey RAK
(SANOFI AVENTIS, Vitry-sur-Seine, France)
08:50Case Study on Automated Fragment Screening
Dr Dennis BREITSPRECHER
(NANOTEMPER TECHNOLOGIES GMBH, Muenchen, Germany)
09:20Practical Demonstration and Handling of the NT.Automated
10:00Coffee break
Speakers' presentations
10:30Biophysical Methods in Drug Discovery: How MST Fits in UCB’s Toolbox ?
Dr Nicolas BASSE
(UCB CELLTECH, Slough, United Kingdom)
11:00Chemical Tractability Assessments with Encoded Library Technology; Probing 82 Bacterial Targets with a 2 Trillion Member DNA Encoded Library
Dr Carl MACHUTTA
(GLAXOSMITHKLINE, Collegeville, United States)
11:30Protein Interaction Analyses: a Basis to Understand Essential Biological Reactions, Infection and Disease Mechanisms
Prof. Dr Peter F. ZIPFEL
(FRIEDRICH SCHILLER UNIVERSITY, Jena, Germany)
12:00Lunch
13:30MST Forum Discussion (moderated discussion)
15:00Coffee break
Speakers' presentations
15:30Application of MicroScale Thermophoresis in Hit Identification and Validation
Dr Markus ZEEB
(BOEHRINGER-INGELHEIM PHARMA, Biberach an der Riß, Germany)
16:00Biophysical Analysis on Membrane Protein Targeting and Assembly
Dr Alexej KEDROV
(GENE CENTER MUNICH, Munich, Germany)
16:30Using MicroScale Thermophoresis to Evaluate UHTS Hits
Mr Edward DINUNZIO
(MERCK, New Jersey, United States)
Selected oral presentations
17:00Structural Basis of SUFU-GLI Interaction in Human Hedgehog Signaling Regulation
Dr Katharina GEGENSCHATZ-SCHMID
(KAROLINSKA INSTITUTET, Huddinge, Sweden)
17:30Concluding remarks
(Please note that this program still might change)

Copyright 2019 LD Organisation sprl  |  rue Michel de Ghelderode 33/02 B-1348  Louvain-la-Neuve (Belgium)  Tel. +32 (0)10 45 47 77  |   |  VAT: BE 0464819842
Developed and powered by Antalys