Drug Analysis 2014
Conferences > Archives > Drug Analysis 2014
Monday June 23, 2014
09:00Opening Ceremony
Marianne FILLET (UNIVERSITY OF LIEGE, Liege, Belgium)
Jacques CROMMEN (UNIVERSITY OF LIEGE, Liege, Belgium)
Session chairs:
Coral BARBAS (SAN PABLO - CEU UNIVERSITY, Madrid, Spain)
Marianne FILLET (UNIVERSITY OF LIEGE, Liege, Belgium)
09:30Building on Success - Metabolic Profiling for Patients and Populations
Ian D. WILSON
(IMPERIAL COLLEGE LONDON, London, United Kingdom)
10:10Towards Personalised Medicine Based on Metabolomics with Mass Spectrometry
Guowang XU
(DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES, Dalian, China)
10:50Coffee Break
Session 1Session 2
Session chairs:
Robert KENNEDY (UNIVERSITY OF MICHIGAN, Michigan, United States)
Guowang XU (DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES, Dalian, China)
11:10Nanoimmunoaffinity Extraction and Analysis of Biomarkers of Oxidative Stress
Michael LÄMMERHOFER
(EBERHARD KARLS UNIVERSITY TÜBINGEN, Tübingen, Germany)
11:40Microflow LC-MS/MS of Human Osteopontin Using an Extended Peptide Internal Standard to Track Digestion and Immunocapture Variability
Thomas KARNES
(VIRGINIA COMMONWEALTH UNIVERSITY, Richmond, Virginia, United States)
12:00Antibody-Free Bioanalysis of Proteins and Peptides in Complex Body Fluids at The PM Level By LC-MS/MS
Rainer BISCHOFF
(UNIVERSITY OF GRONINGEN, Groningen, The Netherlands)
12:20Investigations of Metalloproteins and their Interactions by Affinity Capillary Electrophoresis (ACE)
Hermann WÄTZIG
(TECHNICAL UNIVERSITY BRAUNSCHWEIG, Braunschweig, Germany)
Session chairs:
Eric FRANCOTTE (NOVARTIS, Nuglar, Switzerland)
David LLOYD (BRISTOL-MYERS SQUIBB, New Brunswick, United States)
11:10Is Modern SFC a Viable Alternative to RPLC in Pharmaceutical Analysis?
Davy GUILLARME
(UNIVERSITY OF GENEVA, Geneva, Switzerland)
11:40Definition of a Generic Chiral Separation Strategy on Polysaccharide-Based Chiral Stationary Phases in Supercritical Fluid Chromatography
Debby MANGELINGS
(VRIJE UNIVERSITEIT BRUSSEL, Brussels, Belgium)
12:00Determination of the Enantiomeric Ratio of Drugs Using New SFC-MS/MS Instruments
Maria Kristina PARR
(FREE UNIVERSITY BERLIN, Berlin, Germany)
12:20Quantitative Performances of UHPSFC AND UHPLC: A Comparative Study
Amandine DISPAS
(ULG, LIEGE, Belgium)
12:40Sandwich Lunch and Exhibition
13:40Waters Technical Seminar (30 min)
& Poster Session 1
14:25Poster Session 1
14:25Tutorial: Separation of Enantiomers of Chiral Drugs by Liquid-Phase Techniques
Bezhan CHANKVETADZE
(TBILISI STATE UNIVERSITY, Tbilisi, Georgia)
15:10Coffee Break & Poster Session 1
Session chairs:
Rainer BISCHOFF (UNIVERSITY OF GRONINGEN, Groningen, The Netherlands)
Roman KALISZAN (MEDICAL UNIVERSITY OF GDANSK, Gdansk, Poland)
15:30Pharmacometabolomics: a Tool for Drug Discovery and Personalised Medicine
Coral BARBAS
(SAN PABLO - CEU UNIVERSITY, Madrid, Spain)
Session 3Session 4
Session chairs:
Rainer BISCHOFF (UNIVERSITY OF GRONINGEN, Groningen, The Netherlands)
Roman KALISZAN (MEDICAL UNIVERSITY OF GDANSK, Gdansk, Poland)
16:10Utility of CE-MS and HILIC-MS for Untargeted Analysis of the Anionic Urinary Metabolome
Govert SOMSEN
(VU UNIVERSITY AMSTERDAM, Amsterdam, The Netherlands)
16:40Sheathless Capillary Electrophoresis-Mass Spectrometry: An Enabling Technology for Small-Volume Metabolomics Studies
Rawi RAMAUTAR
(LEIDEN UNIVERSITY, Leiden, The Netherlands)
17:00NMR in the Pharmaceutical and Biomedical Areas for Identification and Quantification of Drugs and Metabolomic Applications
Pascal DE TULLIO
(ULG, Liege, Belgium)
17:20In-Vitro Phenotyping for Toxicological Purposes: New Insights with the Cocktail Approach
Serge RUDAZ
(UNIVERSITY OF GENEVA, Geneva, Switzerland)
Session chairs:
Ulrike HOLZGRABE
(UNIVERSITY OF WUERZBURG, Wuerzburg, Germany)
16:10Analytical Needs within Innovative Manufacturing of Future Pharmaceuticals
Jukka RANTANEN
(UNIVERSITY OF COPENHAGEN, Kobenhavn, Denmark)
16:40Development of a Multiplexed Surface-Enhanced Raman Scattering Quantitatve Approach for Bisphenol Detection
Charlotte DE BLEYE
(ULG, Liege, Belgium)
17:00In-Line Mammalian Cells Culture Monitoring: Comparison of Predictive Performances Offered by NIR and Raman Spectroscopies
David DIDION
(UMONS, Mons, Belgium)
17:20Cell Culture Monitoring by Near Infrared Spectroscopy
Matthieu CLAVAUD
(​F. HOFFMANN - LA ROCHE LTD, ​Kaiseraugst, Switzerland)
18:30Welcome drink
Tuesday June 24, 2014
Session chairs:
Thomas KARNES (VIRGINIA COMMONWEALTH UNIVERSITY, Richmond, Virginia, United States)
Jean-Luc VEUTHEY (UNIVERSITY OF GENEVA, Geneva, Switzerland)
09:00The Nanoliter Lab: Using Droplet Microfluidics to Screen Enzymes and Protein-Protein Interactions
Robert KENNEDY
(UNIVERSITY OF MICHIGAN, Michigan, United States)
09:40Break
Session 5Session 6
Session chairs:
Thomas KARNES (VIRGINIA COMMONWEALTH UNIVERSITY, Richmond, Virginia, United States)
Jean-Luc VEUTHEY (UNIVERSITY OF GENEVA, Geneva, Switzerland)
09:45Development of Selective Extraction Sorbents from the Macro- to the Microscale for the Trace Analysis in Complex Media
Valerie PICHON
(ESPCI, Paris, France)
10:15Coffee Break
10:40In Vivo Monitoring of Neuropeptides In the Rat Hippocampus Using Nano UPLC-ESI-MS/MS
Katrien MAES
(VRIJE UNIVERSITEIT BRUSSEL, Jette, Belgium)
11:00Gas Pressure Assisted Micro-Liquid-Liquid-Extraction-nanoESI-DI-MS: A New Fully-Automated Platform for Bionanalysis
Robert-Jan RATERINK
(LEIDEN UNIVERSITY, Leiden, The Netherlands)
11:20Quantitation of Hepcidin in Dried Blood Spots by Microfluidic LC-CHIP/MS-MS
Virginie HOUBART
(ULG, Liège, Belgium)
11:40Functionalized Polymeric Monolithic Columns in Micro-Hplc for Pharmaceutical Analysis
Zhengjin JIANG
(JINAN UNIVERSITY, Guangzhou, China)
Session chairs:
Vincenza ANDRISANO (UNIVERSITÀ DI BOLOGNA, Rimini, Italy)
Uwe KARST (UNIVERSITY OF MUENSTER, Muenster, Germany)
09:45Analytical Armamentarium for the Structural Characterization of Neo-Glycoproteins
Gabriella MASSOLINI
(UNIVERSITY OF PAVIA, Pavia, Italy)
10:15Coffee Break
10:40Determination of Drug-Albumin Binding Modes by Induced CD Spectroscopy and TD-DFT Calculations
Carlo BERTUCCI
(UNIVERSITY OF BOLOGNA, Bologna, Italy)
11:00Why Capillary Electrophoresis is an Ideal Tool for Drug Screening
Myriam TAVERNA
(UNIVERSITE PARIS SUD, Chatenay Malabry, France)
11:20Immunoaffinity + LC-MS/MS: An Alternative Approach for Antibody Selectivity Evaluation?
Trine G. HALVORSEN
(UNIVERSITY OF OSLO, Oslo, Norway)
11:40Hyphenated Techniques for the Bioanalytical Study of Enzymes
Ann VAN SCHEPDAEL
(KULEUVEN, Leuven, Belgium)
12:00Sandwich Lunch and Exhibition
13:00Thermo Scientific Technical Seminar (30 min)
& Poster Session 2
13:45Poster Session 2
13:45Tutorial: An Analysis of the New USP Validation Guidelines
Bruno BOULANGER
(ULG, Liege, Belgium)
14:30Coffee Break & Poster Session 2
Session chairs:
Carlo BERTUCCI (UNIVERSITY OF BOLOGNA, Bologna, Italy)
Gerhardus J. DE JONG (UTRECHT UNIVERSITY, Utrecht, The Netherlands)
14:50Spatially-Resolved Analysis of Metallopharmaceuticals by Elemental Bioimaging
Uwe KARST
(UNIVERSITY OF MUENSTER, Muenster, Germany)
Session 7Session 8
Session chairs:
Carlo BERTUCCI (UNIVERSITY OF BOLOGNA, Bologna, Italy)
Gerhardus J. DE JONG (UTRECHT UNIVERSITY, Utrecht, The Netherlands)
15:30New Analytical Strategies for Drug Metabolism Studies
Filip CUYCKENS
(JOHNSON & JOHNSON PHARMACEUTICAL, Beerse, Belgium)
16:00Mass Spectrometric Approach for the Characterization of Inhibitors of Amiloyd Aggregation Process
Jessica FIORI
(UNIVERSITY OF BOLOGNA, Bologna, Italy)
16:20Development of Highly Selective LC/MS Assay for Vitamin D Metabolites
Gwenael SCOLAN (SIGMA-ALDRICH, Poole, United Kingdom)
Anders FRIDSTROM (SIGMA-ALDRICH, Buchs, Switzerland)
16:40The Medium-Throughput Determination of Hydrophobicity and Dissociation Constant by LC-MS
Lukasz KUBIK
(MEDICAL UNIVERSITY OF GDANSK, Gdansk, Poland)
Session chairs:
Bezhan CHANKVETADZE (TBILISI STATE UNIVERSITY, Tbilisi, Georgia)
Ann VAN SCHEPDAEL (KULEUVEN, Leuven, Belgium)
15:30Analysis of Large Biomolecules: New Strategies
Jean-Luc VEUTHEY
(UNIVERSITY OF GENEVA, Geneva, Switzerland)
16:00Full Evaporation Headspace Gas Chromatography for Analysis of High Boiling Organic Compounds
Erwin ADAMS
(KULEUVEN, Leuven, Belgium)
16:20Highly Enantioselective Mip-Based Porous Ultra-Thin Film in The Fabrication of an Electrochemical Sensor for the Chiral Analysis of beta-Blockers
Ede BODOKI
("IULIU HATIEGANU" UNIVERSITY OF MEDICINE AND PHARMACY, Cluj-Napoca, Romania)
16:40HPLC Chiral Separation of N-Fluorenylmetoxycarbonyl Alpha-Amino Acids Using Polysaccharide Based Chiral Stationary Phase
Marc JACOB
(PHENOMENEX, Torrance, United States)
17:00Waters Technical Seminar
19:30Banquet
Wednesday June 25, 2014
Session chairs:
Gabriella MASSOLINI (UNIVERSITY OF PAVIA, Pavia, Italy)
Govert SOMSEN (VU UNIVERSITY AMSTERDAM, Amsterdam, The Netherlands)
09:00Proteomics, Bioinformatics and Biopharmaceuticals
Alain VAN DORSSELAER
(UNIVERSITY OF STRASBOURG, Strasbourg, France)
09:40Break
Session 9Session 10
Session chairs:
Gabriella MASSOLINI (UNIVERSITY OF PAVIA, Pavia, Italy)
Govert SOMSEN (VU UNIVERSITY AMSTERDAM, Amsterdam, The Netherlands)
09:45State of the Art Mass Spectrometry Methods for Antibodies, Biosimilars, Bispecifics and ADCs Characterization
Alain BECK
(PIERRE FABRE, St Julien-en-Genevois, France)
10:15Coffee Break
10:40Capillary Electrophoresis - Mass Spectrometry for Characterization of Protein Drugs and Determination of Protein-Protein Interactions
Gerhardus J. DE JONG
(UTRECHT UNIVERSITY, Utrecht, The Netherlands)
11:00In-Depth Glycan Analysis of the Biotherapeutic Enbrel (Etanercept) Using HILIC UPLC/FLR and Mass Spectrometry
Mark HILLIARD
(NATIONAL INSTITUTE FOR BIOPROCESSING RESEARCH & TRAINING, Blackrock, Ireland)
11:20Study of Virus-Like Particles of Human Papillomavirus (HPV-VLP) by Capillary Electrophoresis
Anne-Catherine SERVAIS
(UNIVERSITY OF LIEGE, Liege, Belgium)
11:40Expanding the Role of Capillary Electrophoresis with Mass Spectrometry Detection (CESI-MS) for the Development, Characterization & Control of Biologics
Stephen LOCK
(AB SCIEX, Warrington, United Kingdom)
Session chairs:
Philippe HUBERT (UNIVERSITY OF LIEGE, Liege, Belgium)
Serge RUDAZ (UNIVERSITY OF GENEVA, Geneva, Switzerland)
09:45Analytical Quality by Design
David LLOYD
(BRISTOL-MYERS SQUIBB, New Brunswick, United States)
10:15Coffee Break
10:40Possibilities of Retention Modeling for HILIC and SFC Separations
Eva TYTECA
(VRIJE UNIVERSITEIT BRUSSEL, Elsene, Belgium)
11:00Development of Analytical Methodology to Support a QBD Approach to Formulation Design: A Case Study
Emma QUIRK
(BRISTOL-MYERS SQUIBB, Wirral, United Kingdom)
11:20Surface Acoustic Wave Biosensor as an Analytical Tool in Pharmaceutics: A Quality by Design Approach
Nathalie BRACKE
(GHENT UNIVERSITY, Ghent, Belgium)
11:40Supporting Analytical Quality by Design with Informatics - A Silent Enabler
Dan CHAPMAN
(WATERS CORPORATION, Elstree, Herts, United Kingdom)
12:00Sandwich Lunch and Exhibition
13:00AB Sciex Technical Seminar (30 min)
Session 11Session 12
Session chairs:
Janusz PAWLISZYN (UNIVERSITY OF WATERLOO, Waterloo Ontario, Canada)
Quezia CASS (FEDERAL UNIVERSITY OF SÃO CARLOS, São Carlos, Brazil)
13:45Analytical Microextraction Across Supported Liquid Membranes - Principles, Applications and Recent Developments
Stig PEDERSEN BJERGAARD
(UNIVERSITY OF OSLO, Oslo, Norway)
14:15Preparation of Molecularly Imprinted Polymers for Hydrophilic Compounds by Modified Precipitation Polymerization
Jun HAGINAKA
(MUKOGAWA WOMEN'S UNIVERSITY, Hyogo, Japan)
14:35Validation of the Analytical Procedure for the Determination of the Underivatized Neurotoxin Beta-N-Methylamino-L-Alanine by LC/MS-MS in Environmental Samples and in Human Brain
Audrey COMBES
(ESPCI, Paris, France)
14:55Parallel Artificial Liquid Membrane Extraction (Palme) – An Innovative Implementation of Supported Liquid Membrane Extractions into a Multiwell Plate
Astrid GJELSTAD
(UNIVERSITY OF OSLO, Oslo, Norway)
Session chairs:
Joëlle QUETIN-LECLERCQ (UNIVERSITÉ CATHOLIQUE DE LOUVAIN (UCL), Brussels, Belgium)
Rawi RAMAUTAR (LEIDEN UNIVERSITY, Leiden, The Netherlands)
13:45Quality Control of Chinese Herbal Medicines
Rudolf BAUER
(UNIVERSITY OF GRAZ, Graz, Austria)
14:15Residual Solvents: A Potential Threat Present In Counterfeit Medicines
Eric DECONINCK
(WIV-ISP, Brussel, Belgium)
14:35LC-SPE-NMR Identification and NMR Quantification of Salvia Fruticosa Phytochemicals with Antifungal Activity
Vasiliki EXARCHOU
(UNIVERSITY OF ANTWERP, Antwerp, Belgium)
14:55Synthesis and Degradation Impurities in Peptide Drugs
Matthias D'HONDT
(UGENT, Gent, Belgium)
15:15Break
Session chair:
Stig PEDERSEN BJERGAARD
(UNIVERSITY OF OSLO, Oslo, Norway)
15:20SPME-LC-MS for Drug Bioanalysis, a New Tool for in vivo Sampling and High Throughput Determinations
Janusz PAWLISZYN
(UNIVERSITY OF WATERLOO, Waterloo Ontario, Canada)
16:00Closing remarks

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