8th NovAliX Conference | Hybrid Event

Confirmed Speakers


Keynote Speaker

In-cell NMR: a Powerful Approach for Drug Discovery (KL01)
Prof. Lucia BANCIProf. Lucia BANCI
(UNIVERSITY OF FLORENCE, Sesto Fiorentino, Italy)

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Invited Speakers

Functionalizing Covalent Binders (IL07)
Dr Nir LONDONDr Nir LONDON
(THE WEIZMANN INSTITUTE OF SCIENCE, Rehovot, Israel)

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Positioning Biophysics on the Drug Discovery Map (IL05)
Dr Christine GENICKDr Christine GENICK
(NOVARTIS PHARMA AG, Basel, Switzerland)

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Reactive Fragment Platforms for Covalent Hit ID (IL06)
Dr Emma GRANTDr Emma GRANT
(GLAXOSMITHKLINE, Stevenage, United Kingdom)

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Exploration of Orthogonal E3 Ligases for Targeted Protein Degradation (IL10)
Dr Lena MÜNZKERDr Lena MÜNZKER
(BOEHRINGER INGELHEIM, Wien, Austria)

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Molecular Glues Stabilizing 14-3-3 Protein-Protein Interactions (IL09)
Dr Christian OTTMANNDr Christian OTTMANN
(EINDHOVEN UNIVERSITY OF TECHNOLOGY, Eindhoven, The Netherlands)

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Manipulating RNA Function by Structural Dynamics (IL02)
Prof. Katja PETZOLDProf. Katja PETZOLD
(KAROLINSKA INSTITUTET, Stockholm, Sweden)

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Structure-Based Design of a Phosphotyrosine-Masked, Cell Penetrant Small Molecule Covalently Targeting the E3 Ligase SOCS2 (IL08)
Dr Sarath  RAMACHANDRANDr Sarath RAMACHANDRAN
(UNIVERSITY OF DUNDEE, Scotland, United Kingdom)

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In-cell NMR to study RNA Structure and Folding (IL04)
Prof. Harald SCHWALBEProf. Harald SCHWALBE
(J.W. GOETHE UNIVERSITY FRANKFURT, Frankfurt am Main, Germany)

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Measuring Ligand Binding in Cells Using CETSA® (IL03)
Dr Joseph SHAWDr Joseph SHAW
(ASTRAZENECA, Cambridge, United Kingdom)

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Fluorescent Nucleobase Analogues - minimally Perturbing Labels in Nucleic Acid Biophysics and Bioimaging as well as Drug Discovery (IL01)
Prof. Marcus WILHELMSSONProf. Marcus WILHELMSSON
(CHALMERS UNIVERSITY OF TECHNOLOGY, Gothenburg, Sweden)

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Oral Communications

Binding of Small Molecules to Oligonucleotides in Drug Discovery (OC02)
Dr Nina GROSSMANNDr Nina GROSSMANN
(MERCK HEALTHCARE, Darmstadt, Germany)

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The Use of Dual Targeted Bicycles® to Induce Localised CD137 Agonism (OC04)
Dr Peter BROWNDr Peter BROWN
(BICYCLE THERAPEUTICS, Cambridge, United Kingdom)

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Biophysical Methods Enabling Structure-Based Drug Discovery on Membrane Protein Targets (OC05)
Dr Michael HENNIGDr Michael HENNIG
(LEADXPRO AG, Villigen, Switzerland)

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The Biophysics in the Discovery of Potent cGAS Inhibitors (OC08)
Dr Manuel HILBERTDr Manuel HILBERT
(F. HOFFMANN-LA ROCHE LTD, Basel, Switzerland)

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Structure-based Design of RNA-Binding Small Molecules and their Binding Characterization via MST, (kin)ITC and SwitchSENSE Assays (OC01)
Dr Christian KERSTENDr Christian KERSTEN
(JOHANNES GUTENBERG UNIVERSITY, Mainz, Germany)

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Discovery and Characterization of Active Small Molecule Ligands Targeting the Function of Ubiquitin Specific Protease USP7 by a Catalytic Site Independent Mechanism (OC07)
Prof. Till MAURERProf. Till MAURER
(IDEAYA BIOSCIENCES, South San Francisco, United States)

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Observing Reversible Engagement of KRAS Hotspot Mutants at the Switch-2 Pocket in Cells (OC03)
Mr Matthew ROBERSMr Matthew ROBERS
(PROMEGA, Madison, United States)
Applying Biophysical Interaction Methods to Characterize Binary and Ternary Complex Formation (OC06)
Dr Daniel SCHWARZDr Daniel SCHWARZ
(MERCK KGAA, Darmstadt, Germany)

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Towards Regulation of MDM2 via Stabilisation of a Complex Protein-Protein Interaction (OC09)
Mr Jake WARDMr Jake WARD
(UNIVERSITY OF LEICESTER, Leicester, United Kingdom)

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