| Friday 19/11/2021 |
| 08:00 | Registration |
|
| 08:50 | Opening |
Dr Laurent PROVINS
(UCB, Braine-l'Alleud, Belgium) |
| Session Chair |
Prof Bernard PIROTTE
(ULIÈGE, Liège, Belgium) |
| 09:00 | Short Stories in Medicinal Chemistry (PL01) |
Prof. Gilles BERGER
(ULB, Brussels, Belgium) |
| 09:30 | Purines and Trypanosomatids – a Neglected Match for New Therapeutics? (PL02) |
Dr Fabian HULPIA
(JANSSEN, Beerse, Belgium) |
| 10:00 | Development of Generic G Protein Peptidomimetics Able to Stabilize Active State Gs Protein-Coupled Receptors for Application in Drug Discovery (PL03) |
Prof. Steven BALLET
(VRIJE UNIVERSITEIT BRUSSEL, Brussels, Belgium) |
| 10:30 | Coffee break and Exhibition |
|
| 11:00 | Discovery of GLPG2451, a novel Once Daily Potentiator for the Treatment of Cystic Fibrosis (PL04) |
Dr Hans KELGTERMANS
(GALAPAGOS NV, Mechelen, Belgium) |
| 11:30 | Discovery of Novel Small Molecule Modulators of TNFα Binding and Signalling (PL05)
|
Dr Dan BROOKINGS
(UCB, Slough, United Kingdom) |
| 12:00 | The Confo Therapeutics Technology Platform Enabling GPCR Fragment-Based Drug Discovery (PL06) |
Dr Christel MENET
(CONFO THERAPEUTICS, Brussels, Belgium) |
| 12:30 | Lunch, Exhibition and Poster session |
|
| Session Chair |
Prof. Serge VAN CALENBERGH
(UGENT, Ghent, Belgium) |
| 14:00 | UAMC1110 as the Starting Point for a new Generation of Therapeutics and Diagnostics Targeting Fibroblast Activation Protein (FAP) (PL07) |
Prof. Pieter VAN DER VEKEN
(UANTWERP, Antwerp, Belgium) |
| 14:30 | Step by Step Towards Fully Modified Aptamers | Chemistry Europe Talk (PL08) |
Prof. Eveline LESCRINIER
(REGA INSTITUTE - KU LEUVEN, Leuven, Belgium) |
| 15:00 | Scaffold Development for the Inhibition of FXIIa, a Promising Therapeutic Target (PL09)
|
Dr Lionel POCHET
(UNAMUR, Namur, Belgium) |
| 15:30 | Coffee break and Exhibition |
|
| 16:00 | Meddling with Cell Death Control: Development of MCL-1 Inhibitors for the Treatment of Cancer (PL10) |
Dr Frederik ROMBOUTS
(JANSSEN, Beerse, Belgium) |
| 16:30 | Interrogating the Lactate Dehydrogenase (LDH) Tetramerization Site with (stapled) Peptides (PL11) |
Prof. Raphaël FREDERICK
(UCLOUVAIN, Brussels-Woluwe, Belgium) |
| 17:00 | Development of Positive Allosteric Modulators for Glutamate Ionotropic Receptors (PL12) |
Dr Pierre FRANCOTTE
(ULIÈGE, Liège, Belgium) |
| 17:30 | Closing Remarks |
Prof. Koen AUGUSTYNS
(UNIVERSITY OF ANTWERP, Antwerp, Belgium) |
