Dr Katsunori Tanaka has developed new lysine labeling methods, either by fluorescence or positron emitters for PET, based on his rapid 6Pi-azaelectrocyclization. He efficiently labeled various glycoconjugates (e.g., glycoproteins, glycoclusters, and cell surfaces expressing diverse N-
glycan structures) and successfully imaged the glycan - dependent dynamics in live animals
(i.e., circulatory residence, organ-specific accumulation, trafficking, and metastatic
potential).
Alternatively, Dr Tanaka has synthesized complex-type sialo-N-glycan by efficiently performing the glycosylation (i.e., a-sialylation, B-mannosylation, and N-glycosylation) both on solid supports and inside microfluidic devices.
His research interests include a wide range of natural products fields at the interface of chemistry and biology. For example, exploring new synthetic methods for total synthesis either in microfluidics, live cells, or animals, configurational analysis, biological evaluation, molecular imaging, and molecular recognition of natural products including glycoconjugates.
Experience:
1998-1999 Researcher, Bayer Research Center
1999-2002 Department of Chemistry, Graduate School of Science, Kwansei Gakuin University (Prof. Shigeo Katsumura)
2001-2003 JSPS Research Fellowship for Young Scientists
2002 Ph.D., Department of Chemistry, Graduate School of Science, Kwansei Gakuin University
2002-2005 Postdoctoral Researcher, Department of Chemistry, Columbia University, USA (Prof. Koji Nakanishi)
2003-2005 JSPS Postdoctoral Fellowship for Research Abroad
2005-2012 Assistant Professor, Department of Chemistry, Graduate School of Science,
Osaka University
2012-2017 Associate Chief Scientist, Biofunctional Synthetic Chemistry Laboratory, RIKEN
2012-current Adjunct Professor, Graduate School of Science and Engineering,
Saitama University
2014-current Professor, Alexander Butlerov Institute of Chemistry, Kazan Federal University
2014-current JST (Japan Science and Technology Agency)-PRESTO Researcher
2017-current Group Director, Max Planck-RIKEN Joint Center for Chemical Biology Research
2017-current Deputy Team Leader, GlycoTargeting Research Team
2017-current Chief Scientist, Biofunctional Synthetic Chemistry Laboratory, RIKEN