Bioheterocycles 2015

XVI International Conference on Heterocycles in Bioorganic Chemistry

 Metz, France    June 8-11, 2015

Programme


Session Chair:

Prof. Gilbert KIRSCH
UNIVERSITÉ DE LORRAINE, Metz, France

09:00

Opening

09:30

PL01 - Photoreactive Heterocycles and Natural Product Derivatives

Prof. Dr Thomas LINDEL
TECHNICAL UNIVERSITY OF BRAUNSCHWEIG, Braunschweig, Germany

10:25

Coffee Break

Session Chair:

Prof. Mercedes ÁLVAREZ
UNIVERSITY OF BARCELONA, Barcelona, Spain

10:55

PL02 - Targeting DNA Methylation: a Medicinal Chemistry Approach

Prof. Antonello MAI
UNIVERSITY OF ROME "LA SAPIENZA", Rome, Italy

11:50

IL01 - Synthetic Explorations in Small-ring Azaheterocyclic Chemistry and Development of Novel Bioactive Heterocycles

Prof. Matthias D'HOOGHE
GHENT UNIVERSITY, Ghent, Belgium

12:20

OC01 - Heterocycle-Peptide Hybrids: Synthesis, Conformational Analysis, and Utilization in Medicinal Chemistry

Mr Luca GENTILUCCI
UNIVERSITA DI BOLOGNA, Bologna, Italy

12:35

Lunch

Session Chair:

Prof. Yves FORT
UNIVERSITÉ DE LORRAINE, Nancy, France

14:00

PL03 - The Importance of Heterocycles in Agrochemistry: Fungicides as a Case Study

Dr Harald WALTER
SYNGENTA CROP PROTECTION AG BASEL, Basel, Switzerland

14:55

IL02 - Synthesis of Biorelevant Heterocycles with N-heterocyclic Carbenes

Prof. Andreas SCHMIDT
TECHNICAL UNIVERSITY CLAUSTHAL, Clausthal-Zellerfeld, Germany

15:25

OC02 - Exploiting the Zincke Reaction to Produce Sophisticated Heptamethine Dyes

Dr Robert SMITH
UNIVERSITY OF CENTRAL LANCASHIRE, Prestoin, United Kingdom

15:40

OC03 - Diverse Synthesis of Natural Product Inspired Fused and Spiro-Heterocyclic Scaffolds via Ring Distortion And Construction Strategy

Prof. Subhabrata SEN
SHIV NADAR UNIVERSITY, Gautam Budh nagar, India

15:55

OC04 - Novel Cross-Conjugated Dienones Based on 4-Piperidone Moiety: Synthesis and Antitumor Properties

Dr Mikhail MAKAROV
NESMEYANOV INSTITUTE OF ORGANOELEMENT COMPOUNDS OF RAS, Moscow, Russia

16:10

Coffee Break and Poster Session 1

18:00

Welcome Reception (in the Exhibition area)

Session Chair:

Dr Stéphanie HESSE
UNIVERSITÉ DE LORRAINE, Metz, France

09:00

PL04 - Non Noble Metal Catalysis for Making Precious Molecules

Prof. Matthias BELLER
UNIVERSITY OF ROSTOCK, Rostock, Germany

09:55

IL03 - Synthesis of Novel Alpha7-nAchR Ligands: from an Idea to in Rodent Results for Alzheimer [18F] TEP Imaging

Prof. Sylvain ROUTIER
UNIVERSITÉ D'ORLÉANS, Orléans, France

10:25

OC05 - Recent Advances in the Total Synthesis of Phormidolides B and C

Mr Alejandro GIL ESCOLANO
IRB BARCELONA, Barcelona, Spain

10:40

Coffee Break

Session Chair:

Prof. Patrick CHAIMBAULT
UNIVERSITÉ DE LORRAINE, Metz, France

11:10

PL05 - Metal Catalysis for Heteroarene Synthesis

Prof. Michael GREANEY
THE UNIVERSITY OF MANCHESTER, Manchester, United Kingdom

12:05

IL04 - New Methods in Thioamide Chemistry

Dr Mike PORTER
UNIVERSITY COLLEGE LONDON, London, United Kingdom

12:35

Lunch

Session Chair:

Prof. Ferenc FULOP
UNIVERSITY OF SZEGED, Szeged, Hungary

14:00

PL06 - The Discovery and Development of the HIV Intergrase Inhibitors Dolutegravir and Cabotegravir

Dr Brian JOHNS
GLAXOSMITHKLINE, NC, United States

14:55

IL05 - Are Generic Drugs Only a Copy_and_Paste Products?

Prof. Stanislav RADL
ZENTIVA, Prague, Czech Republic

15:25

OC06 - An Original Domino Radical Cyclisation/Smiles Rearrangement Combination: Application to the Synthesis of Indolo[2,3-b]Quinoline-Type Derivatives

Dr. Stéphane GERARD
UNIVERSITÉ DE REIMS - CHAMPAGNE-ARDENNE, REIMS, France

15:40

OC07 - Palladium-Catalyzed Cross-Coupling Reactions in the Asymmetric Synthesis of Pyrrolo[1,2-b]Isoquinolines

Prof. Nuria SOTOMAYOR
UNIVERSIDAD DEL PAÍS VASCO / EUSKAL HERRIKO UNIBERTSITATEA, Leioa - Bizkaia, Spain

15:55

OC08 - Synthesis of Long Regioregular Dialkyl-Substituted Alpha-Oligofurans

Dr Edward KORSHIN
THE WEIZMANN INSTITUTE OF SCIENCE, Rehovot, Israel

16:10

Coffee Break and Poster Session 2

Session chair:

Prof. John JOULE
UNIVERSITY OF MANCHESTER, Manchester, United Kingdom

09:00

PL07 - Bronsted Acid and Metal-catalyzed Reactions in the Synthesis of Heterocycles

Prof. Esther LETE
UNIVERSIDAD DEL PAÍS VASCO, Bilbao, Spain

09:55

IL06 - Utilization of Hypervalent Iodonium Reagents for the Construction and Functionalization of Heterocyclic Molecules

Dr Zoltan NOVAK
EÖTVÖS UNIVERSITY, Budapest, Hungary

10:25

OC09 - Synthesis of Agrochemistry-Related F-Heterocycles from Novel Fluorinated Diazoalkanes

Dr Pavel MYKHAILIUK
ENAMINE, Kyiv, Ukraine

10:40

Coffee Break

Session Chair:

Dr Harald WALTER
SYNGENTA CROP PROTECTION AG BASEL, Basel, Switzerland

11:15

OC10 - Flavylium-Based Pigments – “Click” Synthesis & Biological Relevance

Dr Stefan CHASSAING
ITAV, Toulouse, France

11:30

OC11 - Synthesis of 7-(2-Aminophenyl)- and 7-(4-Aminophenyl)Guanine, DNA Adducts Derived from the Phenylnitrenium Ion

Prof. Igor LINHART
UNIVERSITY OF CHEMISTRY AND TECHNOLOGY, Prague, Czech Republic

11:45

OC12 - Heterocyclic Coumarine Analogs as Zinc Metalloprotease Inhibitors

Mr Peteris TRAPENCIERIS
LATVIAN INSTITUTE OF ORGANIC SYNTHESIS, RIGA, Latvia

12:00

Lunch

Session chair:

Prof. Milan POTACEK
MASARYK UNIVERSITY, Brno, Czech Republic

13:30

IL07 - Silicon-Containing Tetrahydrocyclopenta[C]Acridine Derivatives as CDKs Inhibitors: Design, Organometallic Synthesis, Metabolic Stability And Optimization

Prof. Philippe BELMONT
UNIVERSITY PARIS DESCARTES, Paris, France

14:00

OC13 - Synthesis of Imidazo-Pyrrolo-Pyrazines/Diazepines/Diazocines via Domino Ugi/Micheal Reaction and Silver-Catalyzed Heteroannulation

Mr Zhenghua LI
KU LEUVEN, Leuven, Belgium

14:15

OC14 - Synthesis and Antifungal Activity of N-Acyl Derivatives of 1,4-Benzoxazin- and 1,4-Benzoxazepin-3-ONES

Mrs Agata GOSZCZYNSKA
WEST POMERANIAN UNIVERSITY OF TECHNOLOGY, SZCZECIN, Szczecin, Poland

14:30

OC15 - Mixed Cu(II) Cu(I) Complexes with Bioheterocycles as the Platform for Construction of Novel Anticancer Agents

Ms Olga KRASNOVSKAYA
MOSCOW STATE UNIVERSITY, Moscow, Russia

14:45

Coffee Break

16:00

Excursions

19:00

Banquet

Session chair:

Prof. Henk VAN DER PLAS
UNIVERSITY OF WAGENINGEN, Wageningen, The Netherlands

09:00

PL08 - Heterocycles Derived from Natural Products in Management of Multidrug Resistance

Prof. Ahcene BOUMENDJEL
UNIVERSITÉ JOSEPH FOURIER, Saint-Martin-d'Hčres, France

09:55

IL08 - At the Crossroads of Chemistry and Biology: Inhibiting Protein Kinase CK2 by Heterocyclic Small Molecules

Prof. Marc LE BORGNE
UNIVERSITÉ CLAUDE BERNARD LYON 1, Lyon, France

10:25

Coffee Break

Session chair:

Prof. Jan BERGMAN
KAROLINSKA INSTITUTE, Huddinge, Sweden

11:00

IL09 - Overcoming Resistance with beta-Lactams

Dr Eric DESARBRE
BASILEA PHARMACEUTICA, Basel, Switzerland

11:30

OC16 - Discovery Of Novel Thieno[3,2-b]Pyrrole 5-Carboxamides as Potent Inhibitors of Chikungunya Virus (CHIKV)

Mr Kuan Chieh CHING
NATIONAL UNIVERSITY OF SINGAPORE, Singapore, Singapore

11:45

Closing