Small-Molecule Modulation of Protein-Protein Interactions (PPIs)
Oegstgeest (near Leiden), The Netherlands April 12-15, 2015
Dinner
Breakfast (as of 7:30)
Introduction
Nuclear Receptor Protein-Protein Interactions
Coffee Break
Nuclear Receptor Protein-Protein Interactions - Part II
Lunch
Stabilization of PPIs: the Other Side of PPI Modulation
Coffee Break
Stabilization of PPIs: the Other Side of PPI Modulation - Part II
Day End
Breakfast (as of 7:30)
Modern Methods for Targeting Low Affinity Protein-Protein Interactions: Structure and Function
Coffee Break
Modern Methods for Targeting Low Affinity Protein-Protein Interactions: Structure and Function - Part II
Lunch
Design and Synthesis of PPI-focussed Chemical Libraries
Coffee Break
Design and Evaluation of Biophysical Assays for the Identification of PPI-Modulators
Day End
Breakfast (as of 7:30)
Developing Small Molecule Inhibitors of Bromodomain-Based Protein-Protein Interactions
Coffee Break
Structure-Based Guided Development & Experimental Validation of a Focused Chemical Library Dedicated to Orthosteric Modulation of Protein-Protein Interactions
Wrap up and Lunch