NovAliX Conference 2013
Biophysics in Drug Discovery

Developing the Synergy between Biophysics and Medicinal Chemistry to Deliver Better Drugs

BφDD 2013

 Strasbourg, France    October 15-18, 2013

Confirmed Speakers

KN01 - Biophysical Methods and Fragment Based Drug Discovery: Targeting Protein-Protein Interactions in Cell Regulatory Systems

Prof. Sir Tom BLUNDELL
Prof. Sir Tom BLUNDELL
UNIVERSITY OF CAMBRIDGE, Cambridge, United Kingdom
Read more

PL04 - Protein Methyltransferase Inhibitors as Personalised Cancer Therapeutics: DOT1L and EPZ-5676

Dr Ann BORIACK-SJODIN
EPIZYME, Cambridge, United States
Read more

PL08 - Backscattering Interferometry: An Enabling Drug Development Technology

Dr Darryl BORNHOP
Dr Darryl BORNHOP
VANDERBILT UNIVERSITY, Nashville, United States
Read more

KN03 - Combining X-Ray Crystallography and Single-Molecule Methods to Probe Antibiotic Inhibition of Translation

Prof. Jamie CATE
Prof. Jamie CATE
UNIVERSITY OF CALIFORNIA, Berkeley, United States
Read more

PL02 - Enabling GPCR Drug Discovery Through Structural and Biophysical Insights

Dr Rob COOKE
Dr Rob COOKE
HEPTARES, Hertfordshire, United Kingdom
Read more

PL10 - Application of SPR Biosensors Throughout the Drug Discovery Process

Prof. Helena DANIELSON
Prof. Helena DANIELSON
UPPSALA UNIVERSITY, Uppsala, Sweden
Read more

PL07 - Label-Free, Immobilisation-Free Interaction Studies Using Microscale Thermophoresis

Dr Stefan DUHR
Dr Stefan DUHR
NANOTEMPER, Munich, Germany
Read more

PL03 - Biophysics to Drive Lead Discovery

Dr Matthias FRECH
Dr Matthias FRECH
MERCK, Darmstadt, Germany
Read more

PL01 - Binding of Drug Substances to Molecular Targets Investigated by Biophysical Methods

Dr Michael HENNIG
Dr Michael HENNIG
F. HOFFMANN-LA ROCHE LTD., Villigen, Switzerland
Read more

PL06 - Can we Use Kinetics and Thermodynamics to Guide Drug Discovery?

Dr Geoff HOLDGATE
Dr Geoff HOLDGATE
ASTRAZENECA, Macclesfield, United Kingdom
Read more

PL09 - Towards Personalised Cancer Medicine with New NMR Tools to Probe Small GTPase Proteins

Dr Chris MARSHALL
Dr Chris MARSHALL
UNIVERSITY OF TORONTO, Toronto, Canada
Read more

PL11 - Finding Active Ligands to kRAS Using Solution State NMR

Dr Till MAURER
Dr Till MAURER
GENENTECH, South San Francisco, United States
Read more

PL12 - Biophysics in Pharmaceutical Lead Discovery

Dr Johannes OTTL
Dr Johannes OTTL
NOVARTIS INSTITUTE OF BIOMEDICAL RESEARCH, Basel, Switzerland
Read more

KN02 - Molecular Mechanism of Action (MMOA) in Drug Discovery

Dr David SWINNEY
Dr David SWINNEY
IRND3, Mountain View, United States
Read more

PL05 - Investing in Knowledge: Combining Biophysical Data in Fragment-Based Drug Discovery

Dr Glyn WILLIAMS
Dr Glyn WILLIAMS
ASTEX PHARMACEUTICALS, Cambridge, United Kingdom
Read more

Oral Communications

OC09 - Identification and Validation of Small Molecule Inhibitors of G Protein Beta 1 Gamma 2

Dr Preeti BAKRANIA
MRC TECHNOLOGY, London, United Kingdom

OC01 - Biophysical Investigations of the Synergistic Activities of Antimicrobial Peptides: New Strategies to Fight Multiresistance

Prof. Burkhard BECHINGER
UNIVERSITY OF STRASBOURG, Strasbourg, France

OC05 - Bringing Light into Antibody Binding Characteristics in Crude Extracts by Means of FCCS

Dr Frank BECKER
Dr Frank BECKER
INTANA BIOSCIENCE GMBH, Planegg, Germany

OC04 - Pharmacokinetics and the Drug-Target Residence Time Concept

Dr Göran DAHL
Dr Göran DAHL
ASTRAZENECA, Mölndal, Sweden

OC02 - X-Ray Crystallography, Kinetic Target-Guided Synthesis and NMR to Unravel the Mode of Action of Insulin Degrading Enzyme Modulators

Prof. Rebecca DEPREZ-POULAIN
Prof. Rebecca DEPREZ-POULAIN
UNIVERSITY OF LILLE, Lille, France

OC07 - Binding Rate Constants Measured on Microliter Volume Using On-Chip Temperature Modulation and Fluorescence Lock-In Detection

Dr Charlie GOSSE
CNRS, Marcoussis, France

OC03 - Residence and Recognition Time and their Use for Structure Kinetic Relationships and for Judging Efficacy of Lead Series

Dr Markku HÄMÄLÄINEN
GE HEALTHCARE BIO-SCIENCES, Uppsala, Sweden

OC10 - Fragments at UCB: Implementation of Non-Covalent Mass Spectrometry and 19F NMR as Orthogonal Screening Techniques

Dr Hannah MAPLE
UCB, Slough, United Kingdom

OC06 - Detection and Analysis of Proteins with an Electro-Switchable DNA Chip

Dr Ralf STRASSER
DYNAMIC BIOSENSORS GMBH, Martinsried, Germany

OC08 - CRYO-TEM: The Way to Answer Real Biological Questions through Unraveling the 3D Mechanistics of Protein

Dr Thomas WOHLFARTH
FEI, Eindhoven/Acht, The Netherlands