7th EFMC Short Course on Medicinal Chemistry - Spring 2013

Tutorial and Exercise 1

Tutorial and Exercise 2

Basic Interactions Types (Ionic, Salt Bridges, H-bonds, etc.)

Non-classical Interactions (Halogen Bonds, Non-Classical H Bonds etc)

Kinetics of Association and Dissociation

Interactions with Proteins Including Interactions within the Binding Cavity (Small Molecule, Cofactors, Water, Residues)

Interactions Between Biological Molecules (Protein-protein, Protein-DNA etc)

Introduction

The Thermodynamics of Interactions

Experimental and Theoretical Assessment of Molecular Interactions

Interactions in the Solid State and with Solvents