MedChem 2013
Constrained Peptides and Macrocycles – New Opportunities for Drug Discovery

Annual One-Day Meeting on Medicinal Chemistry of KVCV & SRC

 Beerse, Belgium    November 22, 2013

Programme


08:00

Registration

08:50

Opening

Dr Lieven MEERPOEL
JANSSEN R&D, Beerse, Belgium

09:00

Cyclic Peptides: Constraining for Conformation vs Bioavailability

Prof. David FAIRLIE
UNIVERSITY OF QUEENSLAND, Brisbane, Australia

09:50

Chemical Space: the Final Frontier. Nanocyclix' Mission: to Explore Strange New Worlds, to Boldly Go Where No Molecule Has Gone Before

Dr Jan HOFLACK
ONCODESIGN, Dijon, France

10:40

Coffee Break

11:15

OC01 - Therapeutic Peptide Lead Finding & Optimization Using High-Throughput Screening of Arrays of Single- and Double-Constrained Clips-Peptides

Prof. Peter TIMMERMAN
PEPSCAN THERAPEUTICS, Lelystad, The Netherlands

11:35

Design and Medical Application of Cyclic Peptides

Dr Horst KESSLER
TECHNISCHE UNIVERSITÄT MÜNCHEN, Garching, Germany

12:25

Lunch Break

14:00

Macrocyclic Drug Design: Ghrelin Agonists as Potential GI Therapeutics

Dr Hamid HOVEYDA
EUROSCREEN, Woluwe-Saint-Lambert, Belgium

14:50

OC02 - Chemoenzymatic Synthesis of Modified Cyclic Peptides

Prof. WAEL HOUSSEN
UNIVERSITY OF ABERDEEN, Old Aberdeen, United Kingdom

15:10

OC03 - Potent and Selective p53-Mdm2 Antagonists: Constrained and Unconstrained

Prof. Alexander DÖMLING
UNIVERSITY OF GRONINGEN, Groningen, The Netherlands

15:30

Coffee Break and Poster session

16:05

A Novel Comprehensive Macrocycle-based Approach to Successful Drug Discovery and Development

Dr Daniel OBRECHT
POLYPHOR, Allschwil, Switzerland

16:55

Synthetic Macrocycles can Unlock New Therapeutic Targets: Opportunities and Challenges in Infectious Diseases

Dr Pierre RABOISSON
JANSSEN PHARMACEUTICAL COMPANIES

17:45

Closing remarks