ASMC'13 Moscow

5th International Symposium on Advances in Synthetic and Medicinal Chemistry

 Moscow, Russia
May 5-8, 2013    

Scientific Program


12:00

Registration

14:00

Pre-symposium Excursions (optional, and subject to registration)

19:30

Welcome Reception

08:30

Opening Ceremony

Session Chair

Prof. Peter H. SEEBERGER
MAX PLANCK INSTITUTE OF COLLOIDS AND INTERFACES, Berlin, Germany
08:50

Targeting Protein Surfaces Using Designed Proteomimetics

Prof. Andrew HAMILTON
UNIVERSITY OF OXFORD, Oxford, United Kingdom
09:40

Design and Optimization of Pyrazinecarboxamide-Based Inhibitors of Diacylglycerol Acyltransferase 1 (DGAT1) Leading to the Clinical Candidate AZD7687

Dr Petra JOHANNESSON
ASTRAZENECA, Mölndal, Sweden
10:20

New Inhibitors of the Enzyme Isoprenylcysteine Carboxyl Methyltransferase (ICMT)

Prof. María del Mar MARTÍN-FONTECHA
COMPLUTENSE UNIVERSITY OF MADRID, Madrid, Spain
10:35

Coffee break and Exhibition

11:05

Oligonucleotide Synthesis Interfaced with Molecular Biology and Nanotechnology

Prof. Marvin CARUTHERS
UNIVERSITY OF COLORADO, Boulder, United States
11:55

BETting on Epigenetic Targets : From Phenotypic Discovery to First Time in Man

Dr Chun-wa CHUNG
GLAXOSMITHKLINE, Stevenage, United Kingdom
12:35

Virtual Screening and Design of New Pharmaceutical Agents Using PASS Approach

Prof. Vladimir POROIKOV
INSTITUTE OF BIOMEDICAL CHEMISTRY, Moscow, Russia
12:50

Lunch and Exhibition

Session Chair

Dr Laurent PROVINS
UCB, Braine-l'Alleud, Belgium
14:00

Synthetic Organic Photochemistry in Batch and Flow

Prof. Kevin BOOKER-MILBURN
UNIVERSITY OF BRISTOL, Bristol, United Kingdom
14:50

The Discovery of the Macrocyclic HCV NS3/4A Protease Inhibitor MK-5172

Dr Michael ROWLEY
MERCK RESEARCH LABORATORIES, Kriens, Switzerland
15:30

Novel Synthetic Chemical Chaperones as a New Basis For Amyotrophic Lateral Sclerosis (ALS) Treatment

Prof. Arie-Lev GRUZMAN
BAR ILAN UNIVERSITY, Ramat Gan, Israel
15:45

Discovery of Highly Potent S1P1 Receptor Antagonists with in vivo Efficacy

Dr Jean QUANCARD
NOVARTIS, Basel, Switzerland
16:00

Coffee break and Exhibition

16:30

A New Approach to Tuberculosis Research: The Lilly TB Drug Discovery Initiative

Dr Philip A. HIPSKIND
ELI LILLY & COMPANY, Indianapolis, United States
17:10

Making Molecular Prosthetics via Iterative Cross-Coupling with MIDA Boronates

Prof. Martin D. BURKE
UNIVERSITY OF ILLINOIS, Urbana, United States
18:00

Closing of the day

21:00

Moscow by Night Tour (free of charge, but subject to registration)

Session Chair

Prof. Hans Ulrich STILZ
NOVO NORDISK, Cambridge, United States
08:30

Versatile Synthetic Methods: Access to Bioactive Molecules

Prof. Janine COSSY
ESPCI PARISTECH, Paris, France
09:20

EFMC Prize for a Young Medicinal Chemist in Academia
Chemical Approaches to Biology and Therapeutics

Prof. Gonçalo BERNARDES
INSTITUTO DE MEDICINA MOLECULAR, PORTUGAL & UNIVERSITY OF CAMBRIDGE, Cambridge, United Kingdom
09:40

EFMC Prize for a Young Medicinal Chemist in Industry
Free-Wilson and Structural Approaches to Co-Optimising Human and Rodent Isoform Potency for 11β-Hydroxysteroid Dehydrogenase Type 1 (11β -HSD1) Inhibitors

Dr Frederick GOLDBERG
ASTRAZENECA, Macclesfield, United Kingdom
10:00

Rapid Kinase SAR Generation: an Integrated Approach to Synthesis, Screening and Molecular Design

Dr David PARRY
CYCLOFLUIDIC LTD, United Kingdom
10:15

Coffee break and Exhibition

10:45

Highly Anti-inflammatory Dendritic Polyglycerol Sulfates - a Multiple Target Approach

Prof. Rainer HAAG
FREE UNIVERSITY BERLIN, Berlin, Germany
11:35

Peptide Chemologics

Dr Lee ROBERTS
PFIZER, Sandwich, United Kingdom
12:15

Discovery of Thienoimidazole-Based HCV NS5A Genotype 1a and 1b Inhibitors

Dr Graeme SMITH
VERTEX PHARMACEUTICALS, Cambridge, United States
12:30

Lunch and Exhibition

13:30

Poster Session 1

Session Chair

Dr Edmond DIFFERDING
DIFFERDING CONSULTING, Louvain-la-Neuve, Belgium
14:30

Organic Molecules as Biological Probes...an exciting journey

Prof. Cristina NEVADO
UNIVERSITY OF ZURICH, Zurich, Switzerland
15:20

Discovery and Initial Clinical Results of [18F]-UCB-H, First PET Radiotracer Targeting Synaptic Vesicle 2A

Dr Anne VALADE
UCB, Braine-l'Alleud, Belgium
16:00

Self-Immolative Spacers in Prodrug/Profluorophore Strategies: Determination of Kinetic Parameters for Release of Single or Multiple Substrates.

Dr Frédéric SCHMIDT
INSTITUT CURIE, Paris, France
16:15

Synthetic Approach to Novel Melatonin Receptor Ligands

Mrs Maria VOLKOVA
MOSCOW STATE UNIVERSITY, CHEMISTRY DEPARTMENT, Moscow, Russia
16:30

Coffee break and Exhibition

17:00

The Design and Characterization of Targeted Covalent Inhibitors of Btk

Dr Eric SCHWARTZ
CELGENE AVILOMICS RESEARCH, Cambridge, United States
17:40

P2X Receptors: ATP-Gated Ion Channels as Novel Drug Targets

Prof. Christa MÜLLER
UNIVERSITY OF BONN, Bonn, Germany
18:30

Closing of the day

Session Chair

Dr Rosa Maria RODRIGUEZ SARMIENTO
F. HOFFMANN-LA ROCHE, Basel, Switzerland
08:30

Harnessing Synergy Between Natural Products and Synthesis Towards Drug Discovery

Prof. Goverdhan MEHTA
UNIVERSITY OF HYDERABAD, Hyderabad, India
09:20

Advances in Targeting Voltage-Gated Sodium Channels with Small Molecules

Dr Antonio NARDI
GRÜNENTHAL, Aachen, Germany
10:00

Design, Synthesis and Application Of Fluorinated Amino Acids as Labels to Study the Membrane Active Peptides by Solid State 19F NMR

Dr Pavel MYKHAILIUK
ENAMINE LTD, Kyiv, Ukraine
10:15

Coffee break and Exhibition

10:45

Engineering of Small Non-Antibody Protein Scaffolds as Novel Biopharmaceuticals: from Anticalins to PASylation

Prof. Arne SKERRA
TECHNICAL UNIVERSITY MUNICH, München, Germany
11:35

Bitopertin (RG1678), a Potent and Selective Glycine Re-Uptake Inhibitor for the Treatment of Schizophrenia

Dr Emmanuel PINARD
F. HOFFMANN-LA ROCHE, Basel, Switzerland
12:15

Fragment-Based Design of Inhibitors of The Antituberculotic Target 1-Deoxy-D-Xylulose-5-Phosphate Synthase Exploiting an Innovative Combination of NMR Techniques

Mrs Tiziana MASINI
UNIVERSITY OF GRONINGEN, Groningen, The Netherlands
12:30

Lunch and Exhibition

13:30

Poster Session 2

Session Chair

Dr Alan D. PALKOWITZ
ELI LILLY & CO.
14:30

New Strategies in Organic Synthesis: Recent Advances Based on Catalytic Reactions of Boron Reagents

Prof. James P. MORKEN
BOSTON COLLEGE, Chestnut Hill, United States
15:20

Identification of a Novel Series of Orexin Receptor Antagonists with a Distinct Effect on Sleep Architecture

Dr Simona COTESTA
NOVARTIS, Basel, Switzerland
16:00

Antibody Drug Conjugates for the Treatment of Cancer

Dr Paul POLAKIS
GENENTECH, San Francisco, United States
16:40

Coffee break and Exhibition

17:10

Metal Catalyzed Arylation of Nucleophiles

Dr Marc TAILLEFER
ENSCM, Montpellier, France
18:00

From Organic Synthesis to Biomedical Sciences - from Polyhydroxybutyrate (PHB) to Cell-Penetrating Peptides

Prof. Dieter SEEBACH
ETH ZURICH, Zürich, Switzerland
18:50

Closing of the day

20:00

Symposium Banquet (optional, and subject to registration)

09:00

Post-symposium Excursions (optional, and subject to registration)