EFMC-ISMC 2014

XXIII International Symposium on Medicinal Chemistry

 Lisbon, Portugal    September 7-11, 2014

Plenary Lectures

Medicinal Chemistry Experts in Pharma are Helping us to Generate Freely Available Novel Probes in Order to Facilitate Target Discovery

Prof. Chas BOUNTRA
Prof. Chas BOUNTRA
UNIVERSITY OF OXFORD, Oxford, United Kingdom
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IUPAC Richter Prize Lecture
Medicinal Chemistry, Quo Vadis? - The Changing Climate In R&D

Dr Helmut BUSCHMANN
Dr Helmut BUSCHMANN
PHARMA CONSULTING AACHEN, Aachen, Germany
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The UCB-Ehrlich Award for Excellence in Medicinal Chemistry
Small Molecule Control Of Intracellular Protein Levels

Prof. Craig CREWS
Prof. Craig CREWS
UNIVERSITY OF YALE, New Haven, United States

Portugal: the Right Place to build Partnerships in Health

Dr Joaquim CUNHA
Dr Joaquim CUNHA
HEALTH CLUSTER PORTUGAL, Maia, Portugal
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The Prous Institute-Overton and Meyer Award for New Technologies i Drug Discovery
Thermodynamics Assisted Drug Discovery

Dr György G. FERENCZY
Dr György G. FERENCZY
HUNGARIAN ACADEMY OF SCIENCES, Budapest, Hungary
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Prof. Gyorgy KESERU
Prof. Gyorgy KESERU
HUNGARIAN ACADEMY OF SCIENCES, Budapest, Hungary
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Plenary Lecture

Dr Sabine HADIDA
Dr Sabine HADIDA
VERTEX PHARMACEUTICALS, San Diego, United States
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The Nauta Award for Pharmacochemistry
Pursuing Compound Quality

Dr Paul LEESON
Dr Paul LEESON
GLAXOSMITHKLINE, Nuneaton, United Kingdom
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High Resolution Mass Spectrometry in Clinical Proteomics

Prof. Dr Matthias MANN
Prof. Dr Matthias MANN
MAX PLANCK INSTITUTE OF BIOCHEMISTRY, Martinsried, Germany

Innovation Through Chemistry at the Interfaces of the Scientific Disciplines

Dr Martin MISSBACH
NOVARTIS, Basel, Switzerland

Partnership between Public and Private Sources: Pharma and IMI Perspective

Dr Paul Peter TAK
Dr Paul Peter TAK
EFPIA, Brentford, United Kingdom
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Plenary Lecture

Prof. Hans WESTERHOFF
Prof. Hans WESTERHOFF
VU UNIVERSITY AMSTERDAM, Amsterdam, The Netherlands
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Invited Speakers

Targeting Spore Germination to Prevent Clostridium Difficile Infections

Dr Ernesto ABEL-SANTOS
Dr Ernesto ABEL-SANTOS
UNIVERSITY OF NEVADA, LAS VEGAS, Nevada, Las Vegas, United States
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Cyclic Peptides from the nature to the synthetic ones

Prof. Fernando ALBERICIO
Prof. Fernando ALBERICIO
INSTITUTE FOR RESEARCH IN BIOMEDICINE, Durban , South Africa
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Sponging Off Nature for New Drug Leads

Prof. Raymond ANDERSEN
Prof. Raymond ANDERSEN
UNIVERSITY OF BRITISH COLUMBIA, Vancouver, Canada
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Omarigliptin: A Once-weekly Oral Antidiabetic Agent

Dr Tesfaye BIFTU
Dr Tesfaye BIFTU
MERCK, Rahway, United States
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Design, Synthesis and Development of Lysophosphatidic Acid Receptor 1 (LPA1) PET Radioligands for Lung Receptor Occupancy Imaging

Dr Sam BONACORSI
Dr Sam BONACORSI
BRISTOL-MYERS SQUIBB, Princeton, United States
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Invited Lecture

Dr Terry BOWLIN
Dr Terry BOWLIN
MICROBIOTIX, Worcester, United States

Being More Certain About Uncertainty In Computational Toxicology Modeling

Dr Scott BOYER
Dr Scott BOYER
KAROLINSKA INSTITUTET, Södertälje, Sweden
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Update on Chemotherapy of Tropical Diseases Caused by Protozoan Parasites

Prof. Reto BRUN
Prof. Reto BRUN
SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE, Basel, Switzerland
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Recent Advances In Asymmetric Catalysis

Prof. Erick M. CARREIRA
Prof. Erick M. CARREIRA
ETH ZÜRICH, Zürich, Switzerland
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Inflammation, Obesity and Metabolic Disease

Dr Ajay CHAWLA
Dr Ajay CHAWLA
UNIVERSITY OF CALIFORNIA, San Francisco, United States
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Efficient Determination Of Protein-Ligand Standard Binding Free Energies And Permeabilities With A Computational Microcalorimeter

Dr Chris CHIPOT
Dr Chris CHIPOT
UNIVERSITY OF ILLINOIS, Urbana, United States
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Binding Affinity Prediction from Molecular Simulation – Soon a Standard Method in Structure-Based Drug Design?

Dr Clara CHRIST
Dr Clara CHRIST
BAYER PHARMA, Berlin, Germany
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Functional and Structural Insights into GPCR Allostery

Prof. Arthur CHRISTOPOULOS
Prof. Arthur CHRISTOPOULOS
MONASH UNIVERSITY, Parkville, Australia
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BETting on Bromodomains: Developing Inhibitors of the Bromodomain-Acetyl-Lysine Interaction

Prof. Stuart CONWAY
Prof. Stuart CONWAY
UNIVERSITY OF OXFORD, Oxford, United Kingdom
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New Stereoselective Organocatalytic Reactions for the Synthesis of Isoquinoline Alkaloids

Prof. Pier Giorgio COZZI
Prof. Pier Giorgio COZZI
UNIVERSITY OF BOLOGNA, Bologna, Italy
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Exploring the Dynamics of Ligand-Protein Interactions using SPR Biosensors

Prof. Helena DANIELSON
Prof. Helena DANIELSON
UPPSALA UNIVERSITY, Uppsala, Sweden
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Breaking The Equilibrium Dissociation Constant Into Fragments: The Use Of Binding Kinetics And Thermodynamics In The Development Of Selective Ligands.

Prof. Iwan DE ESCH
Prof. Iwan DE ESCH
VU UNIVERSITY AMSTERDAM, Amsterdam, The Netherlands
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Exploiting Tumor Metabolic Vulnerabilities with Novel OxPhos Inhibitors

Dr Maria Emilia DI FRANCESCO
Dr Maria Emilia DI FRANCESCO
UTMD ANDERSON CANCER CENTER, Houston, United States
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Visualising Novel Macrolide Antibiotics Bound to Their Ribosomal Target

Prof. Stephen DOUTHWAITE
Prof. Stephen DOUTHWAITE
UNIVERSITY OF SOUTHERN DENMARK, Odensen, Denmark
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A Rational Approach to the Development of Radioligands and PET Ligands for Drug Development

Dr Chad ELMORE
Dr Chad ELMORE
ASTRAZENECA PHARMACEUTICALS, Mölndal, Sweden
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Epigenetic Drug Discovery: Small Molecule Inhibitors of Class IV Bromodomain Proteins

Prof. Paul FISH
Prof. Paul FISH
UCL SCHOOL OF PHARMACY, London, United Kingdom
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Experiences with Natural Product Total Synthesis

Prof. Alois FÜRSTNER
Prof. Alois FÜRSTNER
MAX PLANCK INSTITUT FUR KOHLENFORSCHUNG, Muelheim an der Ruhr, Germany
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Antimalarial Lead Discovery from phenotypic screening: Unraveling the Black Box

Dr Francisco-Javier GAMO
Dr Francisco-Javier GAMO
GLAXOSMITHKLINE, Madrid, Spain
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CNV1014802, a Novel Nav1.7 Selective State-Dependent Sodium Channel Blocker for the Treatment of Chronic Pain: From Discovery to Phase 2 Clinical Study

Dr Gerard GIBLIN
Dr Gerard GIBLIN
CONVERGENCE PHARMACEUTICALS, Cambridge, United Kingdom
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Mechanism-Based Prediction of Drug-Induced Liver Injury

Dr Christopher GOLDRING
Dr Christopher GOLDRING
UNIVERSITY OF LIVERPOOL, Liverpool, United Kingdom
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Integration of New Chemical Diversity and Design Approaches in Lead Generation

Dr Timothy GRESE
Dr Timothy GRESE
ELI LILLY AND COMPANY, Indianapolis, United States
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CB2 Agonists Protect from Inflammation Related Kidney Damage and Fibrosis

Dr Uwe GRETHER
Dr Uwe GRETHER
F. HOFFMANN-LA-ROCHE, Basel, Switzerland
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Mechanoenzymatics of Biomolecular Machines: Free Energies, Dynamics, Function

Prof. Helmut GRUBMÜLLER
Prof. Helmut GRUBMÜLLER
MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY, Göttingen, Germany
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An Introduction To Ion Channels As Drug Targets

Prof. Morten GRUNNET
Prof. Morten GRUNNET
LUNDBECK, Valby, Denmark
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MedChemComm Prize Winner : Phage Selection Of Bicyclic Peptides For Therapeutic Application

Prof. Christian HEINIS
Prof. Christian HEINIS
ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL), Lausanne, Switzerland
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Discovery of the mGlu5 Negative Allosteric Modulator RO4917523

Dr Georg JAESCHKE
Dr Georg JAESCHKE
F. HOFFMANN-LA ROCHE, Basel, Switzerland
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Development of New Anti-Infective Agents and a Novel Delivery Strategy

Prof. Reuben JIH-RU HWU
Prof. Reuben JIH-RU HWU
NATIONAL TSING HUA UNIVERSITY, Hsinchu, Taiwan
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Synthesis of Anti-infective Cyclic Natural Products and Natural Product-like Compounds

Prof. Han-Young KANG
Prof. Han-Young KANG
CHUNGBUK NATIONAL UNIVERSITY, Cheongju, Korea, South
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Bioactive Secondary Metabolites From The Soil And Marine-Derived Fungi Of The Genus Neosartorya

Prof. Anake KIJJOA
Prof. Anake KIJJOA
UNIVERSITY OF PORTO, Porto, Portugal
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Pharmaceutical Protein & Peptide Engineering: From Once Daily To Once Weekly GLP-1 Dosing

Dr Jesper LAU
Dr Jesper LAU
NOVO NORDISK, Maaloev, Denmark
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Translational Modeling in Support to Discovery and Early Development

Dr Thierry LAVE
Dr Thierry LAVE
F.HOFFMANN-LA ROCHE LTD, Basel, Switzerland

Pain-relieving Peptides Targeting Acid-Sensing Ion Channels

Dr Eric LINGUEGLIA
Dr Eric LINGUEGLIA
CNRS-UNIVERSITY OF NICE SOPHIA ANTIPOLIS, Valbonne, France
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Novel Anti-Cancer Treatment Targeting Vps34

Dr Jessica MARTINSSON
Dr Jessica MARTINSSON
SPRINT BIOSCIENCE, Stockholm, Sweden
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High End Design for GPCRs: Combining Protein Structure, Biophysical Data and Computational Water Network Energies

Dr. Jonathan MASON
Dr. Jonathan MASON
HEPTARES THERAPEUTICS, Welwyn Garden City, United Kingdom

Non-Clinical Characterization And Clinical Translation Of LY2811376 And LY2886721

Dr Dustin James MERGOTT
Dr Dustin James MERGOTT
ELI LILLY, Indianapolis, United States
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The Impact of Polypharmacology on Lead Generation

Dr Jordi MESTRES
Dr Jordi MESTRES
IMIM AND UNIVERSITY POMPEU FABRA, Barcelona, Spain

Therapeutic Opportunities Offered by the Excessive Lactate Production in Cancer

Prof. Filippo MINUTOLO
Prof. Filippo MINUTOLO
UNIVERSITY OF PISA, Pisa, Italy
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Metalation of Polyfunctional Heterocyclic Compounds: Applications in Agrochemistry

Dr Marc MOSRIN
Dr Marc MOSRIN
BAYER CROPSCIENCE AG, Frankfurt am Main, Germany
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Successful Drug Discovery And Development Case Studies Of Protein Epitope Mimetics

Dr Daniel OBRECHT
Dr Daniel OBRECHT
POLYPHOR, Allschwil, Switzerland
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A First In Class Chemical Probe For Family VIII Bromodomains

Dr Dafydd OWEN
Dr Dafydd OWEN
PFIZER, Cambridge, United States
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Novel Boron-containing Anti-infective Agents

Dr Jacob PLATTNER
Dr Jacob PLATTNER
ANACOR PHARMACEUTICALS, Palo Alto, United States
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Restoration of Muscle Mass and Lifespan in a Mouse Model of Spinal Muscular Atrophy by Molecular Correction of SMN2 Splicing Defect

Dr Hasane RATNI
Dr Hasane RATNI
F. HOFFMANN-LA ROCHE LTD, Basel, Switzerland
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Antimalarial Trioxolanes - Exploiting Peroxide Reduction For Parasite-Selective Drug Delivery

Dr Adam RENSLO
Dr Adam RENSLO
UNIVERSITY OF CALIFORNIA, San Francisco, United States
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Natural Products as Driving Force for Innovation in Pharmaceutical Research and Development

Dr Esther SCHMITT
Dr Esther SCHMITT
NOVARTIS, Basel, Switzerland
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PET Imaging: Synthesis of Radiopharmaceuticals and their Application in Personalized Medicine and Drug Discovery

Dr Peter J.H. SCOTT
Dr Peter J.H. SCOTT
UNIVERSITY OF MICHIGAN, Ann Arbor, United States
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The Ribosome as a Drug Target: Insights from Structural Investigations - Towards Rational Drug Design

Dr Moran SHALEV BEN AMI
Dr Moran SHALEV BEN AMI
WEIZMANN INSTITUTE, Rehovot, Israel
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New Synthetic Routes of Nitrogen and Oxygen Heterocycles and Related Compounds

Prof. Artur M.S. SILVA
Prof. Artur M.S. SILVA
UNIVERSITY OF AVEIRO, Aveiro, Portugal
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Discovery and Development of Surotomycin for the Treatment of C. difficile

Dr Jared SILVERMAN
Dr Jared SILVERMAN
CUBIST PHARMACEUTICALS, Lexington, United States
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CaV1.3-Selective L-Type Calcium Channel Negative Allosteric Modulators. Novel Therapeutics to Slow the Progression of Parkinson’s Disease

Prof. Rick SILVERMAN
Prof. Rick SILVERMAN
NORTHWESTERN UNIVERSITY, Evanston, United States
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Fragment-Based Discovery of BACE Inhibitors for Alzheimer’s Disease

Dr Andrew STAMFORD
Dr Andrew STAMFORD
MERCK RESEARCH LABORATORIES, Rahway, United States
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Nanobody-Enabled Fragment Screening On Active-State Constrained GPCRs

Prof. Jan STEYAERT
Prof. Jan STEYAERT
VUB, Brussels, Belgium
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1,1’-Spiro-Substituted Hexahydrofuroquinoline Derivatives As Potent And Polar Cholesteryl Ester Transfer Protein (CETP) Inhibitors

Dr Thomas TRIESELMANN
Dr Thomas TRIESELMANN
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG, Biberach an der Riss, Germany
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Strategies to Identify and Manage the Risks of Chemically Reactive Drug Metabolites

Prof. Nico VERMEULEN
Prof. Nico VERMEULEN
VU UNIVERSITY, Amsterdam, The Netherlands
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Cell-Permeable Peptide Therapeutics to Effectively Access Intracellular Targets in Cancer Stem Cells

Dr Jörg VOLLMER
NEXIGEN, Cologne, Germany
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Medicinal Chemistry Optimisation Of Binding Kinetics

Prof. Mike WARING
Prof. Mike WARING
ASTRAZENECA, Newcastle upon Tyne, United Kingdom
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Fast and Safe Synthesis of Pharmaceutically Relevant Molecules

Prof. Thomas WIRTH
Prof. Thomas WIRTH
UNIVERSITY OF CARDIFF, Cardiff, United Kingdom
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Starting Small, Thinking Big: The Application of Fragment Based Drug Discovery to Lead Generation

Dr Steve WOODHEAD
Dr Steve WOODHEAD
TAKEDA CALIFORNIA, San Diego, United States
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Oral Communications

Lectins as Targets in Antiadhesion Therapy - Example of DC-SIGN And FimH Antagonists

Prof. Marko ANDERLUH
Prof. Marko ANDERLUH
UNIVERSITY OF LJUBLJANA, Ljubljana, Slovenia

Covalent Modification of Histones by Nevirapine - A Plausible Pathway to Nevirapine-Induced Cancers?

Dr Alexandra ANTUNES
Dr Alexandra ANTUNES
INSTITUTO SUPERIOR TÉCNICO, Lisbon, Portugal
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Interrogation the Bromodomain Family through Chemical Biology

Dr Steve BELLON
Dr Steve BELLON
CONSTELLATION PHARMACEUTICALS, Cambridge, United States
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A HTS Assay Predicting Both Passive Intestinal Absorption and Affinity Constant Towards Human Serum Albumin in a Two End-Point Measurement

Mr Alban BUJARD
UNIVERSITY OF GENEVA, Geneva, Switzerland

The Discovery of AZD5069; a CXCR2 Antagonist In Phase II Clinical Trials for the Treatment of Asthma

Dr Rhona COX
Dr Rhona COX
ASTRAZENECA, Mölndal, Sweden
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CHF-6001, an Inhaled PDE4 Inhibitor for Asthma and COPD: Synthesis, In Vitro and In Vivo Characterization

Dr Maurizio DELCANALE
Dr Maurizio DELCANALE
CHIESI, Parma, Italy
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Structure-Guided Design of Potent, Selective, Orally Bioavailable Tankyrase Inhibitors

Dr Erin DIMAURO
Dr Erin DIMAURO
AMGEN, Cambridge, United States
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Antagonists of the Pseudomonas Quinolone Signal Receptor (PQSR) as Promising Anti-Virulence Agents

Dr Martin EMPTING
Dr Martin EMPTING
HELMHOLTZ-INSTITUTE F. PHARMACEUTICAL RESEARCH SAARLAND, Saarbrücken, Germany
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P-Glycoprotein/Membrane Role on Multidrug Resistance: Insights from In Silico Studies

Mr Ricardo FERREIRA
Mr Ricardo FERREIRA
FACULTY OF PHARMACY, UNIVERSITY OF LISBON, Lisbon, Portugal
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Covalent Agonists Facilitating Crystallisation of GPCRs

Prof. Peter GMEINER
Prof. Peter GMEINER
FRIEDRICH ALEXANDER UNIVERSITY, Erlangen, Germany
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CRTH2: Can Residence Time Help?

Dr Elena GOMEZ
Dr Elena GOMEZ
ALMIRALL, BARCELONA, Spain
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Discovery of Ivacaftor (Vx-770), a Cftr Potentiator for the Treatment of Cystic Fibrosis in G551d Patients

Dr Sabine HADIDA
Dr Sabine HADIDA
VERTEX PHARMACEUTICALS, San Diego, United States
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Discovery of the First and Only Small Molecule Il-17 Blockers

Dr Nils HANSEN
Dr Nils HANSEN
VIPERGEN, Copenhagen, Denmark
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Discovery of TD-5959 (Batefenterol/GSK-961081): A First-in-Class Dual Pharmacology Multivalent Muscarinic Antagonist and Beta-2 Agonist (MABA) for the Treatment of COPD

Dr Adam HUGHES
Dr Adam HUGHES
THERAVANCE INC., South San Francisco, United States
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The Discovery of APD334, a Selective S1P1 Functional Antagonist

Dr Robert JONES
Dr Robert JONES
ARENA PHARM, SAN DIEGO, United States
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Quantitative Imaging of Mglu5 Allosteric Binding Site and its Occupancy by Positron Emission Tomography with The Novel Fluorine-18 Labelled Probe [18f]Pss232

Dr Stefanie KRAMER
Dr Stefanie KRAMER
ETH ZÜRICH, Zürich, Switzerland
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Biomarkers after Bacteriochlorin Based Photodynamic Therapy against Cancer

Dr Martyna KRZYKAWSKA-SERDA
Dr Martyna KRZYKAWSKA-SERDA
FACULTY OF BIOCHEMISTRY, BIOPHYSICS AND BIOTECHNOLOGY, JAGIELLONIAN UNIVERSITY, Krakow, Poland
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Design, Synthesis and Biological Evaluation of Potent and Selective Class IIA Histone Deacetylase Inhibitors as a Potential Therapy for Huntington's Disease

Dr Christopher LUCKHURST
Dr Christopher LUCKHURST
BIOFOCUS, Saffron Walden, United Kingdom
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Allosteric Protein Kinases Inhibitors for Neurodegenerative Diseases Therapies

Prof. Ana MARTINEZ
Prof. Ana MARTINEZ
INSTITUTO DE QUIMICA MEDICA-CSIC, Madrid, Spain
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Discovery and Characterization of A-366, a Novel, Potent and Highly Selective Inhibitor of Histone Methyltransferase G9a

Dr Michael MICHAELIDES
Dr Michael MICHAELIDES
ABBVIE, North Chicago, United States
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Metal Assisted Synthetic Approaches to Heterocyclic Small Molecules for the Treatment of Cardiovascular Diseases

Prof. Marko D. MIHOVILOVIC
Prof. Marko D. MIHOVILOVIC
VIENNA UNIVERSITY OF TECHNOLOGY, Vienna, Austria
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Development of Novel Building Blocks to Accelerate Drug Discovery

Dr Pavel MYKHAILIUK
Dr Pavel MYKHAILIUK
ENAMINE, Kyiv, Ukraine
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Discovery of Small Molecule Rorγ Modulators for the Treatment of Autoimmune Diseases

Dr Frank NARJES
Dr Frank NARJES
ASTRAZENECA, Mölndal, Sweden
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Discovery of GPR103 Ligands Demonstrating the Anorexigenic Effect in vivo of GPR103 Antagonism

Dr Anneli NORDQVIST
Dr Anneli NORDQVIST
ASTRAZENECA, Mölndal, Sweden
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The Evolution of an in vivo Efficacious Bace1 Inhibitor

Dr Daniel OEHLRICH
Dr Daniel OEHLRICH
JOHNSON & JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT, Beerse, Belgium
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EFMC Prize for a Young Medicinal Chemist in Academia
Inhibitors and Substrates of the Human Lysine Deacylase Enzymes

Prof. Christian A. OLSEN
Prof. Christian A. OLSEN
UNIVERSITY OF COPENHAGEN, Copenhagen, Denmark
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Cadazolid: A New Antibiotic in Development for the Treatment of Clostridium Difficile-Associated Diarrhea (CDAD)

Dr Philippe PANCHAUD
Dr Philippe PANCHAUD
ACTELION PHARMACEUTICALS LTD, Allschwil, Switzerland
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EFMC Prize for a Young Medicinal Chemist in Industry
Design, Synthesis and Properties of Potent Inhibitors of Pseudomonas Aeruginosa Deacetylase LpxC

Dr Grazia PIIZZI
Dr Grazia PIIZZI
NOVARTIS PHARMA, Basel, Switzerland
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Identifying Selective Inhibitors of FGFR4 Kinase

Dr Kurt PIKE
Dr Kurt PIKE
ASTRAZENECA, Cambridge, United Kingdom
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Crystallographic Structures Enable the Discovery of Selective 5-Ht1b Receptor Ligands through Virtual Screening

Dr David RODRIGUEZ DIAZ
Dr David RODRIGUEZ DIAZ
STOCKHOLM UNIVERSITY, Solna, Sweden
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From Malaysian Biodiversity to the Total Synthesis of Dual Inhibitors of BCL-XL and MCL-1 Anti-Apoptotic Protein

Dr Fanny ROUSSI
Dr Fanny ROUSSI
ICSN - CNRS, Gif sur Yvette, France
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Discovery of BAY 1002670 - A Highly Potent and Selective Progesterone Receptor Modulator for Gynecological Therapies

Dr Wolfgang SCHWEDE
Dr Wolfgang SCHWEDE
BAYER, Berlin, Germany
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Cebranopadol, a Novel, Potent Analgesic

Dr Henning STEINHAGEN
Dr Henning STEINHAGEN
GRÜNENTHAL, Verona, Italy
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Novel Potent Inhibitors of the Histone Demethylase KDM1A

Dr Paola VIANELLO
Dr Paola VIANELLO
EUROPEAN INSTITUTE OF ONCOLOGY, Milan, Italy
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Discovery of BAY 85-8501, a Novel and Highly Potent Induced-Fit Binder of Human Neutrophil Elastase for Pulmonary Diseases

Dr Franz VON NUSSBAUM
Dr Franz VON NUSSBAUM
BAYER PHARMA, Berlin, Germany
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Antibodies as Tools to Enable Small Molecule Drug Discovery

Dr Marta WESTWOOD
Dr Marta WESTWOOD
UCB, Slough, United Kingdom
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Improving Physiochemical Properties of a Lapatinib-Based Lead Compound that Targets Trypanosoma Brucei

Prof. Jennifer WOODRING
Prof. Jennifer WOODRING
NORTHEASTERN UNIVERSITY, Boston, United States
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Novel Inhibitors of Alzheimer's Associated Beta-Secretase-Clusters of Heparan Sulfate

Dr Olga ZUBKOVA
Dr Olga ZUBKOVA
VICTORIA UNIVERSITY OF WELLINGTON, Lower Hutt , New Zealand
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