ASMC'11 St. Petersburg

Metal-Catalyzed C–H Bond Functionalizations for Sustainable Synthesis

Chemical Probes for Epigenetics

Novel Metabotropic Glutamate Receptor 4 (mGluR4) Allosteric Potentiators for the Treatment of Parkinsons’s Disease

A few of my Favorite Rings: Catalysis Inspired by Lactones and Lactams

Tofacitinib (CP-690,550): Discovery of a Potent and Selective JAK Inhibitor

Antibody Directed Cytotoxics

From Homer to Hedgehog: Chemistry, Biological Investigations and Medical Perspectives of Cyclopamine

Bicyclic Peptides with Tailored Binding Specificities for Therapeutic Application

Regioselective Reactions on a Chiral Substrate Controlled by the Configuration of a Chiral Catalyst

Discovery and Development of Novel Antimalarials

Target Synthesis Directed Methodology Development

Minor Enantiomer Recycling – A Strategy for Improving Enantioselectivity

Magical Power of d-Block Transition Metals—Pd-Catalyzed Cross-Coupling and Zr-Catalyzed Asymmetric carboalumination of Alkenes (ZACA)

Maitotoxin. An Inspiration for Synthesis

Small Molecules Inhibitors of the WNT Signalling Pathway with Potential Applications in Oncology

Design Strategy for Preparation of Drug-like Polyheterocycles with Privileged Substructures for Discovery of Specific Small Molecule Modulators

Synthesis of Marine Polyketides as Promising Anticancer Agents

GPR119: Knowledge Based Lead Identification

A Step Closer to Hepatitis C Remedy: TMC435, an HCV Protease Inhibitor in Advanced Clinical Trial

The Many Uses of Noncovalent Mass Spectrometry in Early-stage Drug Discovery

The Resurgence of Covalent Drugs

Lessons in Chemoselectivity: Total Synthesis of Polyphenolic Natural Products

Asymmetric Synthesis of Bioactive Molecules

Biochemical Efficiency, a Metrics for an Optimal Molecular Mechanism of Action

Drug Discovery by Programmed Self-Assembly

Bromodomains a New Class of Epigenetic Targets Ripe for Small Molecule Drug Discovery

Validation of N-Myristoyltransferase as a Drug Target

Accelerated C-H Activation Reactions: Enantioselectivity and Positional Selectivity

Small Molecule Inhibitors of the Neuropilin-1 VEGF-A Interaction

Halogen Bonding in Protein–ligand Interactions

The Chemical Biology Consortium- and Experimental Therapeutics Program

Adventures in Medicinal Chemistry and Knowledge Capture

Identification of Bisaryloxy Azetidine Urea Derivatives as Fatty Acid Amide Hydrolase Inhibitors

Identification of Leads from the Tres Cantos Antimalarial Set: Cyclopropyl Carboxamides Show Good Oral Bioavailability and Efficacy In Malarial Animal Models

Highly Efficient Catalytic System for C-H Activation: A Novel and Practical Synthesis of Angiotensin II Receptor Blockers

The Grandisine Alkaloids as Selective δ-Opioid Receptor Agonists; When is a Natural Product not a Natural Product?

Exploring the Rigid Mono- and Diamine Chemical Space

Lead identification of a new class of P2Y12 inhibitors "From a low active and insoluble HTS hit to soluble and active lead compounds"

The Chemistry of Targeting Protein-Protein Interactions: Thinking Outdside of the Box