LD Organisation

Scientific Conference Producers

Programme


08:30

Registration of participants & Introduction
Accueil des participants & Introduction

Session 1
From Natural Products to Drug Discovery
Des produit naturels à la découverte de médicaments

Prof. Pascal RICHOMME
UNIVERSITÉ D'ANGERS, Angers, France
09:30

New Approaches for the Search of New Bioactive Compounds from Higher Plants

Prof. Kurt HOSTETTMANN
UNIVERSITÉ DE GENÈVE SCIENCES II, Genève, Switzerland
10:15

Marine Metabolites as Pharmacophores and Biomedical Research Tools

Prof. Marcel JASPARS
UNIVERSITY OF ABERDEEN, Old Aberdeen, United Kingdom
11:00

Elucidating New Pathways for Natural Product Biosynthesis and Exploiting them for Drug Discovery

Prof. Gregory L. CHALLIS
UNIVERSITY OF WARWICK, Coventry, United Kingdom
12:00

Lunch and Poster
Repas et installation des communications par affiches

13:30

From a Plant to a Drug Candidate S 23906 and Acronycin Derivatives - Illustration of the Complementarity of Industrial and Academic Approaches

Prof. François TILLEQUIN
UNIVERSITÉ PARIS DESCARTES, Paris, France

From a Plant to a Drug candidate S 23906 and Acronycin derivatives Illustration of the complementarity of industrial and academic approaches

Dr. Bruno PFEIFFER
INSTITUT DE RECHERCHES SERVIER, Croissy sur Seine, France
14:15

Venomics – Targeted Drug Discovery in Animal Venoms

Dr. Reto STÖCKLIN
ATHERIS LABORATORIES, Geneva, Switzerland
15:00

Poster Session
Communications par affiches

Session 2
Natural Products Synthesis
Synthèse de produits naturels

Prof. Michael D. THREADGILL
UNIVERSITY OF BATH, Bath, United Kingdom
15:30

Recent Advances in the Total Synthesis of Bioactive Natural Products

Prof. Tony BARRETT
IMPERIAL COLLEGE, London, United Kingdom
16:15

Mimicking "Nature Diversity-Oriented Synthesis": the Manzamine Family of Marine Alkaloids

Dr. Christian MARAZANO
INSTITUT DE CHIMIE DES SUBSTANCES NATURELLES, Gif-sur-Yvette, France
17:00

Synthetic, Structural and Biosynthetic Studies on Mupirocin (Pseudomonic Acid) Biosynthesis

Prof. Tom SIMPSON
UNIVERSITY OF BRISTOL, Bristol, United Kingdom
18:45

Reception at Hôpital St. Jean offered by the municipality of Angers (including a visit of the Apocalypse by Jean Lurçat
Réception à l'Hôpital St. Jean offerte par la municipalité d'Angers (avec un visite de l'Apocalypse de Jean Lurçat

Session 3
Challenging Targets and Approaches
Cibles et approches défiantes

Prof. Gerard DELERIS
UNIVERSITY BORDEAUX SEGALEN, Bordeaux, France
08:45

Chromenone- and Pyranone-Based Inhibitors of DNA Damage-Activated Kinases as Antitumour Agents

Prof. Roger J. GRIFFIN
NEWCASTLE UNIVERSITY, Newcastle upon Tyne, United Kingdom
09:30

"Prix Charles Mentzer"
Development and Biological Evaluation of Prodrugs for a Selective Treatment of Cancer

Prof. Lutz F. TIETZE
GEORG-AUGUST-UNIVERSITÄT, Göttingen, Germany
10:15

Coffee break
Pause café

10:35

P-Glycoprotein - from Inhibitor Design to Substrate Prediction

Prof. Gerhard ECKER
EFMC, UNIVERSITY OF VIENNA, Vienna, Austria
11:20

Targeting DNA and Protein-Protein Interactions

Dr. Mark SEARCEY
UNIVERSITY OF EAST ANGLIA, Norwich, United Kingdom

Mini-Session

Chemical Biology, Life Sciences and Drug Discovery: How to Promote "Cross-Talks"?

Prof. Gerard DELERIS
UNIVERSITY BORDEAUX SEGALEN, Bordeaux, France
Dr Yves ROLLAND
SOCIÉTÉ DE CHIMIE THÉRAPEUTIQUE, Châtenay-Malabry, France
12:45

Lunch
Repas

Career Opportunities Session from 14:00 to 15:30
Session carrières de 14h à 15h30

Dr. Robert H. DODD
ICSN CNRS, Gif-Sur-Yvette, France
13:45

Chemical Diversity and Biotransformation: Metabolomics Based Approaches

Mr. Bernard WALTHER
TECHNOLOGIE SERVIER, Orleans, France
14:30

Inhibitors of Heterotrimeric G-Protein Signalling: A New Strategy for Anti Cancer Therapy

Dr. Grégoire PREVOST
GROUP IPSEN, Les Ulis, France
15:15

Poster Session
Ciommunications par affiches

Session 4
Tools and Approaches
Outils et apporches

Prof. Tom SIMPSON
UNIVERSITY OF BRISTOL, Bristol, United Kingdom
16:00

Finding New Biologically Active Natural Products via HTS: Reality or Utopia

Dr. Delphine JACQUOT
MERCK KGAA, Darmstadt, Germany
16:45

High Thoughput Physicochemical Profiling in Drug Discovery - Equilibria and Dynamics

Dr Richard TAYLOR
UCB, Slough, United Kingdom
17:30

ADME/Tox: a New Tool for Medicinal Chemistry

Dr. Christian FILAQUIER
CENTRE DE RECHERCHE PIERRE FABRE, Castres, France

Gala Dinner at "Greniers St. Jean"
Dîner de gala aux Greniers St. Jean

Session 5
Tools and Approaches
Outils et approches

Prof. Janos SAPI
SCT & UNIVERSITY OF REIMS-CHAMPAGNE-ARDENNE, Reims, France
08:45

Approaches to the Design of Kinase Inhibitors by Molecular Modeling

Dr. Pascal FURET
NOVARTIS PHARMA INC, Basel, Switzerland
09:30

"Paul Ehrlich" Lecture
Some Recent Advances in Drugs and Nanomaterials Development for Therapeutical Applications

Dr Frédéric TARAN
CEA/SACLAY, Gif-sur-Yvette, France
10:15

Coffee break
Pause café

Prof. Marcel JASPARS
UNIVERSITY OF ABERDEEN, Old Aberdeen, United Kingdom
10:35

A Multidisciplinary Approach Leading to the Discovery of a Novel RSV Fusion Inhibitor

Dr Jean-François BONFANTI
TIBOTEC, A DIVISION OF JANSSEN-CILAG, Val de Reuil, France
11:20

Identification of activin-like kinase 5 (ALK5) inhibitors for the treatment of fibrosis: chronicle of a toxicity foretold

Dr. Françoise GELLIBERT
SERVIER, Suresnes Cedex, France
12:15

Lunch
Repas

Session 6
Carbohydrates
Hydrates de carbone

Dr Luc VAN HIJFTE
JANSSEN RESEARCH & DEVELOPMENT, Nijmegen, The Netherlands
13:45

From Automated Oligosaccharide Synthesis to a Malaria Vaccine

Dr. Bastien CASTAGNER
ETH, Zürich, Switzerland
14:30

Design, Synthesis and Properties of SSR126517E, a Biotinylated Antithrombin Pentasaccharide

Dr. Gilbert LASSALLE
SANOFI-AVENTIS, Toulouse, France
15:15

Closing
Conclusions