Optional tours between 09.00-18.00 / Pushkin (Amber room) + Pavlovsk Palaces, three Cathedrals (tbc), Canals
Transfers from the airport between 12.00-19.00
Registration
Welcome reception
Opening
The Changing Face of Organic Synthesis
Protecting Group Directed Ring-Closing Metathesis (RCM): the First Total Synthesis of Anti-Malarial Nonenolide
Coffee-break
Discovery of Innovative Small Molecule Therapeutics
The Discovery of Novel Antiviral Agents
Ultra-High-Throughput Screening for Lead Discovery: Impact of Combinatorial Chemistry Compound Libraries
A Combinatorial Approach to Probe the Mechanism of Binding of Bivalent Ligands to GPCRs
Lunch
Polyfunctional Zn,Mg-Organometallics for Organic Synthesis
Innovation in Drug Discovery and Development Interface
From Adrenomedullin Positive Modulators to A New Type Of Mmp-2 Inhibitors
Coffee-break
Surprises and Discoveries with Natural Products
Discovery of Bile Acid Resorption Inhibitors
Tetracyclic Indole Inhibitors of Hepatitis C Virus Ns5b-Polymerase
Metal-Catalyzed Coupling Reactions
City tour for participants
Positive and Negative Modulation of Family C GPCRs
New Sugar-Derived Compounds with Anti-Septic Shock, Anti-Inflammatory and Anti-Ischemia Activity
Coffee-break
Genomic and Nongenomic Bile Acid Receptors as New Targets for Drug Discovery
The Identification of Secretase Inhibitors for the Treatment of Alzheimer's Disease
Where Chemistry meets Sphingolipid Biology
Synthesis of Fosmidomycin Analogues Modified at the Three-Carbon Spacer: Towards Potent Antimalarials
Lunch & Poster session
BUSINESS MINI SYMPOSIUM: Discovery Chemistry Outsourcing Opportunities in Russia
Opening
A Renewed Emphasis on Partnerships, With a Twist; The Challenge to Meet the Ever Evolving Pharma Landscape
Discovery Chemistry Sourcing in Russia. How Does it Compare to Other Regions of the World?
Outsourcing Parts of the Discovery Value Chain in Russia
The AstraZeneca Compound Collection Enhancement Programme - Outsourcing in Russia
Outsourcing in Russia: the UCB Experience
Discovery Chemistry CROs: The Art of Playing on the Fast Changing Field
Coffee-break
Panel discussion participants
City tour for participants
New Approaches to Biologically Validated Molecules using Chemoselective Ligation Reactions
Discovery of Aclidinium Bromide, a New Long-Acting Muscarinic Antagonist for COPD Therapy
Novel Multilabeled Oligonucleotides Containing 1-phenylethynylpyrene ara-2´-uridine-carbamate and LNA: Synthesis and Photochemical Properties
Coffee-break
Exploiting High Throughput Screening: Case Histories
Design and Synthesis of Thrombin Receptor Antagonists for the Prevention of Thrombosis
Lunch
Free afternoon - optional tours to Hermitage, Russian Museum, 3 Cathedrals and Canals
Chemical Probes of Carbohydrate Biosynthetic Pathways in Mycobacterium Tuberculosis
Discovery and Development of Kinase Iinhibitors by Targeting Conformational Switch Pockets. A General Platform that is Unique for Targeting ATP Pockets
Synthesis of (±)-Cephalotaxine via Diallylboration-Ring Closing Metathesis-Bromocyclocarbamation Sequence
Coffee-break
SAHA (Vorinostat), an FDA Aapproved Anticancer Compound with a Novel Mechanism of Action
The Fight Against AIDS: New Avenues for Inhibiting RT, an Old Target
Adventures in Medicinal Chemistry
Smiles Rearrangement and Isocyanide Chemistry
Lunch & Poster session
Transition Metal Catalyzed Reactions of Carbon-Carbon and Carbon-Heteroatom Bond Formation
The Power of Semi-Synthesis: The Discovery of Torisel ™
Synthesis and Characterisation of Novel Orally Available Dopamine D3 Receptor Antagonists
Coffee-break
A Systems Based Approach to Protein Kinase Research Leads to the Discovery of Tykerb, a Dual Inhibitor of EGFR and erbB2 Tyrosine Kinases
Olefin Metathesis Catalysts for the Synthesis of Large and Small Molecules
Closing
Symposium banquet (optional)
Following the banquet, Open bridges tour(optional)