Registration
The registration desk will
remain open during the whole symposium.
Welcome Reception
From 17:30 -
18:30, in the hall of the Mezhdunarodnaya Hotel.
Opening
Perspectives in Total Synthesis
Coffee break
Biomimetic Oxidations of Organic Substrates
Studies on Bioactive Macrocycles: New Concepts and Spin-offs
Lunch
"IN SILICO" Design and Focused Synthesis of New Neuroactive Compounds in the Series of Glutamate Receptors Ligands
Coffee break
Catalytic Asymmetric Synthesis of Pharmaceuticals
Drug Discovery - Back to the Future
BANQUET
Buffet dinner at the Presidency
of the Academy of Science.
Challenges in Drug Discovery: Design and Synthesis of Novel Drug Candidates
Application of Enabling Technologies to Expedite Drug Discovery
Designing Selective Kinase Inhibitors: Tools, Concepts, Challenges and Opportunities
Electrophilic Fluorodesilylation of Organosilanes a New Synthetic Route to Various Fluorinated Compounds
Coffee break
Design and Synthesis of Enzyme Inhibitors - From Concepts to Practice
Indoline and Indolenine Intermediates in the Syntheses of Complex Indole Derivatives
Molecular Diversity from Acylnitroso Cycloadditions: Preparation of Novel Scaffolds and Focused Targets
ViagraTM & Beyond: Selective PDE5 Inhibitors for Treatment of MED
Application of Chemogenomic Principles to Library and Template Design
Lunch
Structure-Based Design of Nonpeptidic Enzyme Inhibitors: Molecular Recognition Studies with Biological Receptors
SAR By XRay: A New Approach Combining Screening and Rational Drug Design. Application to the Discovery of Nanomolar Src SH2 Binders
Molecular Design, Chemical Synthesis and Biological Evaluation of Quinoxaline-Carbohydrate Hybrids as Novel and Selective Photo-Induced Dna Cleaving and Cytotoxic Agents
Coffee break
From Synthetic Polyelectrolites to Vaccinating Macromolecules
Arene-Arene Interactions Between the Substrate and the Organocatalyst as the Driving Force In the Asymmetric Allylation of Aldehydes with Allyltrichlorosilanes.
Asymmetric Approach to Proline-Derived Spiro-Β-Lactams - Staudinger Reaction of N-Protected-4-Methanesulfonyloxy-L-Proline with N-Aryl Imines
Hit and Lead Generation - Beyond High Throughput Screening
Optional:
Swan Lake Ballet at
the Bolshoï Theater
Moscow by night guided tour (First departure)
Moscow by night guided tour (Second departure)
Synthesis and Pharmacological Characterization of Novel Epothilone Derivatives
The Discovery of BIBN4096, a Novel CGRP Antagonist for the Treatment of Migraine
The Synthesis of Biarylthioether derivatives as GlyT1 Inhibitors
Catalytic Synthesis of Azoles, or Teaching an Old Dog New Tricks
Coffee break
New Multicomponent Reactions
Computer-Aided Discovery of New Pharmacological Agents With Multiple Mechanisms Of Action
Dysinosins B – D, Inhibitors Of Factor Viia And Thrombin From The Australian Sponge Lamellodysidea Chlorea
LMW Agonists for the Human LH Receptor: Identification, Optimisation and Mechanism of Action
Solution Phase Combinatorial Chemistry: Enabling Technologies for Heterocyclic Synthesis
Lunch
Research Collaborations and Technology Integration
Compound Collection Enhancement Activities in AstraZeneca
Developing and Managing Discovery Chemistry Collaborations
Coffee break
The Impact of Out-sourcing on R&D Productivity
Chemical Outsourcing: Beyond Routine Work
10 Years of Discovery Chemistry Outsourcing in Russia: From Compound Acquisition to Strategic Research Collaborations
OPERA PERFORMANCE at NEW OPERA THEATER
Progress in the Total Synthesis of Polycyclic Natural Products
The Construction of the Chiral Quaternary Carbon in Drug Discovery Directed towards the Novel Neuroprotective Agent E2050
Fluorinated Azaheterocycles in Medicinal Chemistry
Coffee break
Polycycles from Polyenes, Seeking Opportunities for Organic Synthesis
Tris-(2-Hydroxyethyl) Ammonium Salts of Aryl Heteroacetic Acids – New Class of Drugs And Biologically Active Compounds
Practical Considerations in Predicting ADMET Properties from Chemical Stucture
Lunch
KREMLIN GUIDED TOUR
Optional:
Evgeny Onegin at the
Bolchoï Theater
Optional:
TOUR 1 Tretiakov Galery + Cathedral of Christ the Saviour
Optional:
TOUR 2 Pushkin Museum + Cathedral of Christ the Saviour