Target Selection through Application of Chemical and Systems Biology
Castle "Oud Poelgeest", Oegstgeest, The Netherlands April 1-4, 2012
Dinner
Drug Discovery in the Century of Systems and Chemical Biology
Close
Breakfast
Modelling of Physiological Processes to Understand Disease
Lost in Translation (?)
Optimizing Lead Compound Selection Using Mechanistic Physiological Modeling
Coffee Break
Physiological and Disease Modelling for Diabetes: Glucose/insulin Homeostasis
Qualifying Mechanistic Physiological Models for Use in Pharmaceutical Discovery and Development, Part I
Lunch
Qualifying Mechanistic Physiological Models for Use in Pharmaceutical Discovery and Development, Part II
Coffee Break
Modelling of Cellular Systems: Helping you to Identify the Most Relevant Switches
Comparative Logical Models of Signalling Networks in Normal and Transformed Hepatocytes
End day-1, followed by a social event
Breakfast
Modelling of EGFR Signalling for Target Identification
The Virtual Pancreatic Beta-cell: a Mod & Sim Approach in Diabetes Drug Discovery
Coffee Break
Models of Signalling Networks: from Coarse Boolean Approaches to Dynamic Models of Underlying Biochemistry
Lunch
Chemical and Systems Biology Approaches for Target Identification
Targets and Molecular Mechanisms: Charting Kinase Inhibitors in Malignant Diseases Using Chemical Proteomics
Coffee Break
Computational Approaches to Target Prediction
End day-2
Breakfast
Review Tools and Case Studies for Computational Drug Repositioning
Review Computational Methods and Case Studies for Understanding Disease Mechanisms and Drug Responses
Coffee Break
Using cMap and MANTRA to identify Drug Repositioning Opportunities
Summary
Lunch and depart