RICT 2012 - Interfacing Chemical Biology and Drug Discovery

48th International Conference on Medicinal Chemistry
48èmes Rencontres Internationales de Chimie Thérapeutique

 Poitiers, France    July 4-6, 2012

Programme


08:00

Registration

09:00

Welcome session

Session 1: Case Studies (Kinase)

Session Chairman

Dr Pascal GEORGE
SCT & INDEPENDENT SCIENTIFIC EXPERT & ADVISER, Longvilliers, France
09:15

Translating Structural-biology & Preclinical Activity of Nilotinib into Efficacy in Leukemia Patients

Dr Paul W. MANLEY
NOVARTIS PHARMA, Basel, Switzerland
10:00

Matched Triplicate Design Sets in the Optimisation of a New Series of Glucokinase Activators

Prof. Mike WARING
ASTRAZENECA, Newcastle upon Tyne, United Kingdom
10:45

Coffee Break

Session 2: Non Classical Drugs

Session Chairman

Dr Samir JEGHAM
SANOFI R&D, MONTPELLIER, France
11:15

Synthetic Carbohydrates in the Search for Tailor-made Antibacterial Vaccines: Shigellosis as a Challenge

Dr Laurence MULARD
PASTEUR INSTITUTE, Paris, France
12:00

Bicyclic Peptide Antagonists Isolated From Phage Display Libraries

Prof. Christian HEINIS
ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL), Lausanne, Switzerland
12:45

Lunch and Poster Presentation

Session Chairman

Prof. Vincent LISOWSKI
UNIVERSITÉ DE MONTPELLIER 1, Montpellier, France
14:15

A Look at Some Innovative Chemical Aspects in Medicinal Chemistry, about Heterocycles, Microwaves, Chemical Libraries, Boronics and Garlands
Paul Ehrlich Prize Lecture

Prof. Sylvain RAULT
UNIVERSITÉ DE CAEN, Caen Cedex, France

Session 3: Targeted Therapies

Session Chairman

Prof. Jean-Pierre GESSON
UNIVERSITÉ DE POITIERS, Poitiers, France
15:00

Squalenoyl Nanomedicines as Potential Therapeutics

Dr Didier DESMAËLE
UNIVERSITÉ PARIS SUD, Châtenay-Malabry, France
15:45

Coffee Break and Poster Session

Session Chairman

Prof. Jean-Pierre GESSON
UNIVERSITÉ DE POITIERS, Poitiers, France
16:15

Protein-binding Prodrugs and Drug Conjugates in Oncology: From Design, Applications to Combination Therapy

Prof. Felix KRATZ
TUMOR BIOLOGY CENTER, Freiburg, Germany
17:00

Potent Antibody Drug Conjugates for Cancer Therapy: From the Lab to a Clinically Approved Drug

Dr Peter SENTER
SEATTLE GENETICS, Bothell, United States
17:45

Final Announcements

18:00

Booster Presentations Exhibitors

09:00

Start of sessions

Session 4: Case Studies (mGLU)
Session 5: Targets and Pathways
Session 4: Case Studies (mGLU)
Session Chairman
Dr Luc VAN HIJFTE
SCT & NOVALIX, Nijmegen, The Netherlands
Session 5: Targets and Pathways
Session Chairman
Prof. Dario NERI
ETH ZÜRICH, Zürich, Switzerland
10:30

Coffee Break and Poster Session

11:45

Start of sessions

Session 6: Epigenetics
Session 7: New Tools / Platforms
Session 6: Epigenetics
Session Chairman
Prof. Yves CENATIEMPO
UNIVERSITÉ DE POITIERS, Poitiers Cedex, France
Session 7: New Tools / Platforms
Session Chairman
Dr Olivier LAVERGNE
., Palaiseau, France
12:30

Lunch and Poster Session

15:30

Start of sessions

Session 8: Exploring Chemical Space-Fragments
Session 9: Case Studies (CNS)
Session 8: Exploring Chemical Space-Fragments
Session Chairman
Prof. Janos SAPI
SCT & UNIVERSITY OF REIMS-CHAMPAGNE-ARDENNE, Reims, France
Session 9: Case Studies (CNS)
Session Chairman
Dr Edmond DIFFERDING
DIFFERDING CONSULTING, Louvain-la-Neuve, Belgium
16:15

Coffee Break and Poster Session

Session Chairman

Dr Pascal GEORGE
SCT & INDEPENDENT SCIENTIFIC EXPERT & ADVISER, Longvilliers, France
17:00

Two Chemical/Biological Approaches to Alzheimer's Disease: Prevention and Therapy
Charles Mentzer Prize Lecture

Dr Laurent MEIJER
MANROS THERAPEUTICS, Roscoff, France
17:45

Final Announcements

18:00

Booster Presentations

Session 10: Case Studies (Kinase)

Session Chairman

Dr Bernat VIDAL
ALMIRALL, Barcelona, Spain
08:45

Antagonists of the p53/hdm2 Protein-Protein Interaction - Path to the Clinic

Dr Carlos GARCIA-ECHEVERRIA
SANOFI, Vitry sur Seine, France
09:30

Sorafenib – A Signal Transduction Inhibitor for the Treatment of Liver Cancer

Dr Bernd RIEDL
BAYER PHARMA, Wuppertal, Germany
10:15

Coffee Break and Poster Session

Session Chairman

Dr. Vincent DIVE
CEA, Gif-sur-Yvette, France
10:45

Poster Awards and Labex Presentations

Session 11: Future trends in MedChemBio

Session Chairman

Prof. Joachim MITTENDORF
BAYER PHARMA AG, Wuppertal, Germany
11:30

Perspectives in Structure and Fragment Based Drug Discovery

Prof. Rod HUBBARD
UNIVERSITY OF YORK / VERNALIS, York, United Kingdom
12:15

Targeting Protein Interactions Mediated by Epigenetic Acetyl-lysine Reader Domains of the Bromodomain Family

Prof. Stefan KNAPP
OXFORD UNIVERSITY, Oxford, United Kingdom
13:00

Final Conclusions

13:15

Lunch

14:00

End of Symposium