SPICA 2012

International Symposium on Preparative and Industrial Chromatography and Allied Techniques

 Brussels, Belgium    September 30

Lectures confirmed to date

Quality by Design in API Purifications. Making the Right Things

Dr Alessandro BUTTE
Dr Alessandro BUTTE
ETH ZURICH, Zurich, Switzerland
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Molecular Modeling of the Affinity Chromatography of Proteins: Status and Perspectives

Prof. Carlo CAVALLOTTI
Prof. Carlo CAVALLOTTI
POLITECNICO DI MILANO, Milano, Italy
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Molecular Engineering of Multiple Weak Interactions for High Selectivity Bioseparations

Prof. Steven CRAMER M
Prof. Steven CRAMER M
RENSSELAER POLYTECHNIC INSTITUTE, Troy, United States
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Implementation of a Continuous Chromatography Step in The Synthesis of an API – Combining Chemistry and Chromatography to Achieve Better Economics

Dr Olivier DAPREMONT
AMPAC FINE CHEMICALS, Rancho Cordova, United States
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New Approaches to Food Fractionation by Chromatography: Adapting High-Cost Techniques to the Production of Moderate-Value Products

Prof. Conan FEE
Prof. Conan FEE
UNIVERSITY OF CANTERBURY, Christchurch, New Zealand
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Biological Production of Peptides

Prof. Susanna LEONG
Prof. Susanna LEONG
NANYANG TECHNOLOGICAL UNIVERSITY, Singapore, Singapore
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Oral Communications

Purification of Proteins from Human Blood Plasma by Multicolumn Solvent Gradient Purification

Mr Daniel BAUR
ETH ZÜRICH, Zurich, Switzerland

Distributed Pore Surface Model

Ing Niklas BORG
LUND UNIVERSITY, Lund, Sweden

Towards Optimally Sized Centrifugal Partition Chromatography Columns - Process Design Methodology and Applications

Mr Sebastien CHOLLET
GEPEA LABORATORY, Saint-Nazaire, France

A Model Based Approach to Reducing the Analytical Burden of High Throughput Screening

Dr Marcus DEGERMAN
LUND UNIVERSITY, Lund, Sweden

Liquid-Liquid Extraction of Biomolecules - Process Development and Integration into Downstream Processing

Mr Jan Kristof EGGERSGLUESS
CLAUSTHAL UNIVERSITY OF TECHNOLOGY, Clausthal, Germany

Characterization of Adsorption in SFC: an Evaluation of Methods Used in LC

Prof. Torgny FORNSTEDT
Prof. Torgny FORNSTEDT
KARLSTAD UNIVERSITY, Karlstad, Sweden

New Trend in Material Development for Peptide Purification

Dr Nicola FORRER
ZEOCHEM, Uetikon am See, Switzerland

Preparative Chiral Chromatography: What Can Go Wrong and How to Solve it

Dr Pilar FRANCO
CHIRAL TECHNOLOGIES, INC, Illkirch, France

From Racemate to Single Enantiomer with 100% Yield by Process Integration of SMB and Enzymatic Racemization

Mr Markus FUEREDER
ETH ZURICH, Basel, Switzerland

Modeling Protein Adsorption Equilibria on Ion-Exchange Resins

Dr Bertrand GUELAT
NOVARTIS PHARMA AG, Basel, Switzerland

Quality by Design with Rigorous Process Modeling as Platform Technology of the Future

Mr Christoph HELLING
CLAUSTHAL UNIVERSITY OF TECHNOLOGY, Clausthal-Zellerfeld, Germany

Experimental Study on a Binary Chromatographic System Subject to a Mixed Competitive-Cooperative Adsorption Isotherm

Mr Simon JERMANN
ETH ZÜRICH, Zurich, Switzerland

Separation of Bionanoparticles and Biological Superstructures

Prof. Alois JUNGBAUER
Prof. Alois JUNGBAUER
UNIVERSITY OF NATURAL RESOURCES AND APPLIED LIFE SCIENCES, Vienna, Austria

Integrated Chromatographic Processes for the Production of Pure Enantiomers

Prof. Malte KASPEREIT
Prof. Malte KASPEREIT
FRIEDRICH-ALEXANDER UNIVERSITY ERLANGEN-NÜRNBERG, Erlangen, Germany

Model Mismatch Resolution and Optimization for Simulated Moving Bed and Continuous Chromatographic Processes

Prof. Yoshiaki KAWAJIRI
Prof. Yoshiaki KAWAJIRI
GEORGIA INSTITUTE OF TECHNOLOGY, Atlanta, United States

A Non-Conventional Application of Simulated Moving Bed Technology: Purification of a Complex Mixture

Ms Kiara KOCHENDOERFER
UNIVERSITY ERLANGEN-NUREMBERG, Ludwigshafen, Germany

Model Based Design and Integration of Crystallization Processes of Natural Products in Down Stream Processing

Mr Iraj KOUDOUS
INSITUT FÜR THERMISCHE VERFAHRENS- UND PROZESSTECHNIK, Clausthal-Zellerfeld, Germany

Continuous Synthesis and Purification Through Direct Combination of a Flow Reactor and Simulated Moving Bed Chromatography

Dr Ju Weon LEE
Dr Ju Weon LEE
MAX-PLANCK-INSTITUTE FOR DYNAMICS OF COMPLEX TECHINCAL SYSTEMS, Magdeburg, Germany

Nanofiltration of Peptides in Acetonitrile/Water Mixtures: Process Development

Ms Patrizia MARCHETTI
LONZA, Visp, Switzerland

Continuous Purification of Single-Chain Antibody Fragments by Simulated Moving Bed Chromatography

Mr Carlos Andres MARTINEZ CRISTANCHO
MAX-PLANCK-INSTITUT MAGDEBURG, Magdeburg, Germany

Design Of Tailor-Made Stationary And Mobile Phase In Liquid-Liquid Chromatography

Prof. Mirjana MINCEVA
Prof. Mirjana MINCEVA
UNIVERSITÄT ERLANGEN, Freising, Germany

Relay SMB: A Simple and Efficient Way of Implementing Simulated Moving-Bed Chromatography

Prof. José Paulo MOTA
Prof. José Paulo MOTA
REQUIMTE/CQFB, FFCT, Caparica, Portugal

Enabling High Purities and Yields in Therapeutic Peptide Purification by Using Continuous Chromatography (MCSGP)

Dr Thomas MÜLLER-SPÄTH
CHROMACON AG, Zurich, Switzerland

Efficient API Purification or How Combining OSN and Chromatography Increases Your Process Yields!

Dr Muriel NASSO
EVONIK, Wembley, United Kingdom

Modeling of Protein Aggregation in Preparative Chromatography

Prof. Bernt NILSSON
Prof. Bernt NILSSON
LUND UNIVERSITY, Lund, Sweden

Peptidomimetic Affinity Ligands (PALs) - A Powerful Approach to Improving DSP Performance

Dr Matthias PASCHKE
3B PHARMACEUTICALS GMBH, Berlin, Germany
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Shifting the Scale-up Limits of Disposable Downstream Processing

Mr. Marcel RAEDTS
PROXCYS BV, Nieuw Amsterdam, The Netherlands
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Optimization of Simulated Moving Bed Processes for Multicomponent Chiral Separations

Dr António E. RIBEIRO
Dr António E. RIBEIRO
POLYTECHNIC INSTITUTE OF BRAGANÇA, Braganca, Portugal

Supercritical Fluids as the Desorbent for Simulated Moving Bed? Application to the Concentration of Triterpenoids from Taiwanofugus Camphorate

Ms Liang RU CHIEN
I SHOU UNIVERSITY, Kaohsiung City, Taiwan

Chromatographic Process Options for Reduced Purities

Prof. Tuomo SAINIO
Prof. Tuomo SAINIO
LAPPEENRANTA UNIVERSITY OF TECHNOLOGY, Lappeenranta, Finland

Study of Hydrodynamics in Chromatographic Columns by Computed X-Ray Tomography and its Evaluation by CFD Simulations

Ms Irma SCHMIDT
UNIVERSITY ERLANGEN-NUREMBERG, Erlangen, Germany

Scalable Technology for the Extraction of Pharmaceuticals (STEP): Progress on Developing Versatile Small Footprint Technology for Continuous Processing at the Lab Scale up to 1 Kg/Day

Prof. Ian SUTHERLAND
BRUNEL INSTITUTE FOR BIOENGINEERING, Uxbridge, United Kingdom
Dr Svetlana IGNATOVA
Dr Svetlana IGNATOVA
BRUNEL UNIVERSITY, Uxbridge, United Kingdom

A Reaction-Separation Integrated Process for the High-Yield Synthesis of Rare Sugars

Ms Nina WAGNER
ETH ZURICH D-BSSE, Basel, Switzerland

Integration of Hydrophobic Interaction- and Ion Exchange Chromatography

Mr Tim WELLSANDT
INSITUT FÜR THERMISCHE VERFAHRENS- UND PROZESSTECHNIK, Clausthal-Zellerfeld, Germany

A New Disposable Technology for Chromatographic Purification of Biopharmaceuticals

Dr David YAVORSKY
MERCK-MILLIPORE, Bedford, United States

Workshops

From Development to Commercial Scale: Rules to Scale up, QbD, Regulatory, Process Validation

Dr Alessandro BUTTE
Dr Alessandro BUTTE
ETH ZURICH, Zurich, Switzerland
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Process Design for Purification of Biomolecules

Prof. Alois JUNGBAUER
Prof. Alois JUNGBAUER
UNIVERSITY OF NATURAL RESOURCES AND APPLIED LIFE SCIENCES, Vienna, Austria

Multicolumn Processes: from Historical SMB to the Latest Advances in the Purification of Biomolecules

Prof. Arvind RAJENDRAN
Prof. Arvind RAJENDRAN
UNIVERSITY OF ALBERTA, Edmonton, AB, Canada

Preparative HPLC : Phase Screening, Method Optimization, Process Development. Troubleshooting a Preparative Chromatographic Device

Dr Michael SCHULTE
MERCK, Darmstadt, Germany

Process Design for Purification of Small Molecules

Prof. Jochen STRUBE
CLAUSTHAL UNIVERSITY OF TECHNOLOGY, Clausthal-Zellerfeld, Germany

Solving a Purification Process: Choice of the Appropriate Process (Batch vs Continuous, Low Pressure vs High Pressure, Liquid vs SFC, Centrifugal Partition Chromatography vs Countercurrent Chromatography)

Dr Eric VALERY
NOVASEP CDMO, AN AXPLORA COMPANY, Pompey, France