LD Organisation

Scientific Conference Producers

14:00

Registration

18:00

Welcome Reception

19:00

Live Performance of Cypriot and Greek Songs by the Choir of Karavas Organization

08:00

Welcome and Opening remarks

08:40

Natural Product Synthesis: A Stimulus for Discovery

Prof. Steven V. LEY
UNIVERSITY OF CAMBRIDGE, Cambridge, United Kingdom
09:30

Coffee break and Poster session

10:00

Multidimensional Lead Optimization: The Discovery of Innovative Small Molecule Therapeutics

Prof Magid ABOU-GHARBIA
TEMPLE UNIVERSITY, Philadelphia, United States
10:50

Reactivity and Applications of a New Diene for Organic Synthesis

Prof. Erik SORENSEN
PRINCETON UNIVERSITY, Princeton, United States
11:30

The Discovery of Non Transition-State Isostere BACE Inhibitors

Dr Philippe NANTERMET
MERCK AND CO., WEST POINT, United States
12:00

Lunch and Poster session

14:00

Mini Business Symposium and Panel Discussion

14:01

Chemistry in Drug Discovery: New Trends and New Challenges. Coordinator: Dr Ron Magolda, Wyeth Research, Princton, USA. Participants: to be announced

14:02

New Trends in Chemistry Outsourcing. Coordinator: Dr Eugene Vaisberg, ChemBridge, San Diego, USA. Participants: to be announced

08:00

Synthetic Investigations of Antimitotic Agents

Prof. Madeleine JOULLIÉ
UNIVERSITY OF PENNSYLVANIA, Philadelphia, United States
08:50

From Chemistry to Medicine: New Chemical Reactions and New Synthetic Molecules Leading to New Therapies for Inflammation and Cancer

Prof. Nicos A. PETASIS
UNIVERSITY OF SOUTHERN CALIFORNIA, LOS ANGELES, United States
09:30

Coffee break and Poster session

10:00

Structure-based Design of Nuclear Receptor Hormone Ligands: Potent Quinoline-based Liver X Receptor (LXR) Agonists

Dr Ronald MAGOLDA
WYETH RESEARCH, Monmouth Junction,, United States
10:30

TAFIa Inhibitors for Treatment of Thrombosis

Dr Mark BUNNAGE
PFIZER, Boston, United States
11:00

From the Insoluble Dye Indirubin Towards Highly Active, Soluble CDK2-Inhibitors

Dr Rolf JAUTELAT
SCHERING, Berlin, Germany
11:30

Discovery of Pyrido-Pyrimidone Based Selective and Orally Efficacious p38 MAP Kinase Inhibitors

Dr Swaminathan (Ravi) NATARAJAN
MERCK, Rahway, United States
12:00

Lunch and Poster session

14:00

A Multi-dimensional Approach to Molecular Recognition in Chemistry and Biology: Towards New Antimalarial Therapies

Prof. François DIEDERICH
ETH ZURICH, Zürich, Switzerland
14:50

Towards Measuring and Modulating Protein Function with Small Molecules

Prof. Nicolas WINSSINGER
UNIVERSITY OF STRASBOURG, Strasbourg, France
15:30

Coffee break

15:50

Discovery and Optimization of Novel Drug Like Molecules via the ConTourTM Design Technology

Dr David CLAREMON
VITAE PHARMACEUTICAL, Fort Washington, United States
16:20

Development of Transition Metal Catalyzed Reaction for Organic Synthesis

Prof. F. Dean TOSTE
UNIVERSITY OF CALIFORNIA, Berkeley, United States
08:00

Structure-based Organic Synthesis of Drug Prototypes

Prof. Stephen HANESSIAN
UNIVERSITY OF MONTREAL, MONTREAL, QC, Canada
08:50

Chemistry and Biology of Heterocycles: From Combinatorial Chemistry to Natural Product Synthesis

Prof. Stefan BRAESE
UNIVERSITY OF KARLSRUHE, KARLSRUHE, Germany
09:30

Coffee break and Poster session

10:00

Stereoselective Synthesis of Biologically Active Alkaloids

Prof. David TANNER
THE TECHNICAL UNIVERSITY OF DENMARK, LYNGBY, Denmark
10:40

Geometric Control of Alkenes in Organic Synthesis

Prof. Jun'ichi UENISHI
KYOTO PHARMACEUTICAL UNIVERSITY, KYOTO, Japan
11:20

Natural Products; Targets of Opportunities

Prof. Emmanuel THEODORAKIS
UNIVERSITY OF CALIFORNIA SAN DIEGO, La Jolla, United States
12:00

Lunch and Poster session

14:00

Excursion Details to be announced

19:00

Nicolaou Group Re-union Dinner

08:00

Melatonin, a Hormone in the Dark

Prof. Peter J. GARRATT
UNIVERSITY COLLEGE LONDON, London, United Kingdom
08:50

Synthesis Adventures with Bases and Bridges

Prof. Nigel SIMPKINS
UNIVERSITY OF NOTTINGHAM, NOTTINGHAM, United Kingdom
09:30

Coffee break an dPoster session

10:00

Biocatalysis: Key Element in the Synthesis of Bioactive Heterocycles and Natural Products

Prof. Floris RUTJES
RADBOUD UNIVERSITY NIJMEGEN, Nijmegen, The Netherlands
10:40

Study towards the Total Synthesis of Micrandilactone A

Prof. Zhen YANG
PEKING UNIVERSITY, BOSTON, United States
11:20

Inhibition of the Formation of the Transcription Activation Complex by the Thyroid Hormone Receptor

Dr Rodney KIP GUY
ST. JUDE CHILDREN'S RESEARCH HOSPITAL, Memphis, United States
12:00

Lunch and Poster session

14:00

Asymmetric Two-Center Catalysis: Construction of Tetrasubstituted Carbons

Prof. Masakatsu SHIBASAKI
UNIVERSITY OF TOKYO, Tokyo, Japan
14:50

The Catalytic Cycle of Discovery in Total Synthesis

Prof. Phil BARAN
THE SCRIPPS RESEARCH INSTITUTE, La Jolla, United States
15:30

Coffee break

16:40

The Art of Total Synthesis at the Limits of Chemical Complexity

Prof. K.C. NICOLAOU
THE SCRIPPS RESEARCH INSTITUTE, Houston, United States
17:00

Closing

19:00

Banquet